He, S., Wu, Z., Tian, Y., Yu, Z., Yu, J., Wang, X., Li, J., Liu, B., and Xu, Y. *(2020) Structure of nucleosome-bound human BAF complex.Science 367, 875-881（徐彦辉课题组，*为通讯作者）

Zheng, H., Qi, Y., Hu, S., Cao, X., Xu, C., Yin, Z., Chen, X., Li, Y., Liu, W., Li, J., Wang, J., Wei, G., Liang, K., Chen, F. X.*, and Xu, Y.* (2020) Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase. Science 370, eabb5872（徐彦辉课题组、陈飞课题组，*为通讯作者）

Li, J.-T., Yin, M., Wang, D., Wang, J., Lei, M.-Z., Zhang, Y., Liu, Y., Zhang, L., Zou, S.-W., Hu, L.-P., Zhang, Z.-G., Wang, Y.-P., Wen, W.-Y., Lu, H.-J., Chen, Z.-J., Su, D., and Lei, Q.-Y.* (2020) BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma. Nature Cell Biology 22, 167-174（雷群英课题组，*为通讯作者）

Xu GL*, Bochtler M*. Reversal of nucleobase methylation by dioxygenases. Nat Chem Biol. 2020 Nov;16(11):1160-1169. （徐国良团队，*为通讯作者）

Huang, Y., Wang, H., Hao, Y., Lin, H., Dong, M., Ye, J., Song, L., Wang, Y., Li, Q., Shan, B., Jiang, Y., Li, H., Shao, Z., Kroemer, G., Zhang, H., Bai, L., Jin, T., Wang, C., Ma, Y., Cai, Y., Ding, C., Liu, S.*, Pan, Y.*, Jiang, W.*, and Zhou, R.* (2020) Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity. Nature Cell Biology（柳素玲课题组，*为通讯作者）

Qin, Y., Chen, W., Jiang, G., Zhou, L., Yang, X., Li, H., He, X., Wang, H.-l., Zhou, Y.-b., Huang, S., and Liu, S.* (2020) Interfering MSN-NONO complex–activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer. Science Advances 6, eaaw9960（柳素玲课题组，*为通讯作者）

Jiao, F., Li, Z., He, C., Xu, W., Yang, G., Liu, T., Shen, H., Cai, J., Anastas, J. N., Mao, Y., Yu, Y., Lan, F., Shi, G. Y., Jones, C., Xu, Y., Baker, S.*, Shi, Y.*, and Guo, R.* (2020) RACK7 recognizes H3. 3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma. Science Advances 6, eaba2113（表观遗传团队，*为通讯作者）

Li, W., Karwacki-Neisius, V., Ma, C., Tan, L., Shi, Y., Wu, F.*, and Shi, Y. G.* (2020) Nono deficiency compromises TET1 chromatin association and impedes neuronal differentiation of mouse embryonic stem cells. Nucleic Acids Research（表观遗传团队，*为通讯作者）

Li S, Feng J, Wu F*, Cai J, Zhang X, Wang H, Fetahu IS, Iwanicki I, Ma D, Hu T, Liu H, Wang B, Shi G, Tan L*, Shi YG.* TET2 promotes anti-tumor immunity by governing G-MDSCs and CD8+ T-cell numbers. EMBO Rep. 2020 Sep 14;21(10):e49425.（表观遗传团队，*为通讯作者）

Chen, Y., Lyu, R., Rong, B., Zheng, Y., Lin, Z., Dai, R., Zhang, X., Xie, N., Wang, S., Tang, F.*, Lan, F.*, and Tong, M.-H.* (2020) Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks. Cell Research（蓝斐课题组，*为通讯作者）

Wan, J., Xing, S., Ding, L., Wang, Y., Gu, C., Wu, Y., Rong, B., Li, C., Wang, S., Chen, K., He, C., Zhu, D., Yuan, S., Qiu, C., Zhao, C., Nie, L., Gao, Z., Jiao, J., Zhang, X., Wang, X., Ying, T., Wang, H., Xie, Y.*, Lu, Y.*, Xu, J.*, and Lan, F.* (2020) Human-IgG-Neutralizing Monoclonal Antibodies Block the SARS-CoV-2 Infection. Cell Reports 32, 107918-107918（蓝斐课题组，徐建青课题组，*为通讯作者）

Liu, Z., Yang, Y., Gu, A., Xu, J., Mao, Y., Lu, H., Hu, W., Lei, Q.-Y., Li, Z., Zhang, M., Cai, Yu.*, and Wen, W.* (2020) Par complex cluster formation mediated by phase separation. Nature Communications 11, 1-18（温文玉*为通讯作者）

Tang, D.-J., Du, X., Shi, Q., Zhang, J.-L., He, Y.-P., Chen, Y.-M., Ming, Z., Wang, D., Zhong, W.-Y., Liang, Y.-W., Liu, J.-Y., Huang, J.-M., Zhong, Y.-S., An, S.-Q., Gu, H.*, and Tang, J.-L.* (2020) A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA. Nature Communications 11, 2794（顾宏周课题组，*为通讯作者）

Xia K, Shen J, Li Q, Fan C*, Gu H*. Near-Atomic Fabrication with Nucleic Acids. ACS Nano. 2020 Feb 25;14(2):1319-1337.（顾宏周课题组，*为通讯作者）

Zhang, W., Xu, L., Park, H.-B., Hwang, J., Kwak, M., Lee, P. C., Liang, G., Zhang, X., Xu, J., and Jin, J.-O.* (2020) Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy. Nature Communications 11, 1-14（徐建青/张晓燕团队，*为通讯作者）

Yang, Y., Liu, X., Shen, C., Lin, Y., Yang, P., and Qiao, L.* (2020) In silico spectral libraries by deep learning facilitate data-independent acquisition proteomics. Nature Communications 11, 1-11（乔亮课题组，*为通讯作者）

Li, Y., Li, J., Wang, R., Zhang, L., Fu, G., Wang, X., Wang, Y., Fang, C., Zhang, D., Du, D., Ma, X., Pan, M., Guo, Q., Xu, X., Hu, X., Zhou, Y., Mo, S., Wang, H., Gao, J., Huang, S., Liu, Y., Cai, S., Hua, G.*, Peng, J.*, and Yu, F.-X.* (2020) Frequent RNF43 mutation contributes to moderate activation of Wnt signaling in colorectal signet-ring cell carcinoma. Protein & Cell（余发星课题组*为通讯作者）

Xu, D., Yang, M., Capitano, M., Guo, B., Liu, S., Wan, J., Broxmeyer, H. E.*, and Huang, X.* (2020) Pharmacological activation of nitric oxide signaling promotes human hematopoietic stem cell homing and engraftment. Leukemia, 1-6（黄鑫欣课题组，*为通讯作者）

 Qu, R., Dong, L., Zhang, J., Yu, X., Wang, L.*, and Zhu, S.* (2020). Cryo-EM structure of human heptameric Pannexin 1 channel. Cell Research, 1-3.（王磊课题组，*为通讯作者）

Zheng, W., Zhou, Z., Sha, Q., Niu, X., Sun, X., Shi, J., Zhao, L., Zhang, S., Dai, J., Cai, S., Meng, F., Hu, L., Gong, F., Li, X., Fu, J., Shi, R., Lu, G., Chen, B., Fan, H., Wang, L., Lin, G.*, and Sang, Q.* (2020) Homozygous Mutations in BTG4 Cause Zygotic Cleavage Failure and Female Infertility. The American Journal of Human Genetics 107, 1-10（桑庆课题组，*为通讯作者）

Zhang, Z., Li, B., Fu, J., Li, R., Diao, F., Li, C., Chen, B., Du, J., Zhou, Z., Mu, J., Yan, Z., Wu, L., Liu, S., Wang, W., Zhao, L., Dong, J., He, L., Liang, X., Kuang, Y., Sun, X., Sang, Q.*, and Wang, L.* (2020) Bi-allelic Missense Pathogenic Variants in TRIP13 Cause Female Infertility Characterized by Oocyte Maturation Arrest. American Journal of Human Genetics 107, 15-23（王磊课题组，桑庆课题组，*为通讯作者）

Zhao, L., Xue, S., Yao, Z., Shi, J., Chen, B., Wu, L., Sun, L., Xu, Y., Yan, Z., Li, B., Mao, X., Fu, J., Zhang, Z., Mu, J., Wang, W., Du, J., Liu, S., Dong, J., Wang, W., Li, Q., He, L., Jin, L., Liang, X., Kuang, Y., Sun, X., Wang, L.*, and Sang, Q.* (2020) Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development. Protein & Cell（王磊课题组，桑庆课题组，*为通讯作者）

Ding, J., Zhao, J., Huan, L., Liu, Y., Qiao, Y., Wang, Z., Chen, Z., Huang, S., Zhao, Y.*, and He, X.* (2020) Inflammation-induced LINC00665 increases the malignancy through activating PKR/NF-kappa B pathway in hepatocellular carcinoma.Hepatology. 2020 Feb 21.（何祥火团队，*为通讯作者）

Li Z, Lu X, Liu Y, Zhao J, Ma S, Yin H, Huang S, Zhao Y*, He X*. Gain of LINC00624 Enhances Liver Cancer Progression by Disrupting the HDAC6-TRIM28-ZNF354C Corepressor Complex. Hepatology. 2020 Sep 1.（何祥火团队，*为通讯作者）

Wu, Y. J., Zhao, Y. M., Huan, L., Zhao, J. J., Zhou, Y. Q., Xu, L. G., Hu, Z. X., Liu, Y. Z., Chen, Z. A., Wang, L., Huang, S. L.*, He, X. H.*, and Liang, L. H.* (2020) An LTR Retrotransposon-Derived Long Noncoding RNA lncMER52A Promotes Hepatocellular Carcinoma Progression by Binding p120-Catenin. Cancer Res. 80, 976-987（何祥火团队，*为通讯作者）

Huan, L., Guo, T., Wu, Y., Xu, L., Huang, S., Xu, Y.*, Liang, L.*, and He, X.* (2020) Hypoxia induced LUCAT1/PTBP1 axis modulates cancer cell viability and chemotherapy response. Molecular Cancer 19（何祥火团队，*为通讯作者）

Xu L, Huan L, Guo T, Wu Y, Liu Y, Wang Q, Huang S, Xu Y*, Liang L*, He X*. LncRNA SNHG11 facilitates tumor metastasis by interacting with and stabilizing HIF-1α. Oncogene. 2020 Oct 15.（何祥火团队，*为通讯作者）

Mei, X.*, Qi, D., Zhang, T., Zhao, Y., Jin, L., Hou, J., Wang, J., Lin, Y., Xue, Y., Zhu, P., Liu, Z., Huang, L., Nie, J., Si, W., Ma, J., Ye, J., Finnell, R., H , Saiyin, H., Wang, H.*, Zhao, J.*, Zhao, S.*, and Xu, W.*(2020) Inhibiting MARSs reduces hyperhomocysteinemia‐associated neural tube and congenital heart defects. EMBO Molecular Medicine（赵世民/徐薇课题组，*为通讯作者）

Xia, Y.-K., Zeng, Y.-R., Zhang, M.-L., Liu, P., Liu, F., Zhang, H., He, C.-X., Sun, Y.-P., Zhang, J.-Y., Zhang, C., Song, L., Ding, C., Tang, Y.-J., Yang, Z., Yang, C., Wang, P., Guan, K.-L., Xiong, Y., and Ye, D.* (2020) Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network. Protein & Cell（MCB团队，*为通讯作者）

Cheng, Z.-L., Zhang, M.-L., Lin, H.-P., Gao, C., Song, J.-B., Zheng, Z., Li, L., Zhang, Y., Shen, X., Zhang, H., Huang, Z., Zhan, W., Zhang, C., Hu, X., Sun, Y.-P., Jiang, L., Sun, L., Xu, Y., Yang, C., Ge, Y., Zhao, Y., Liu, X., Yang, H., Liu, P., Guo, X., Guan, K.-L., Xiong, Y., Zhang, M., and Ye, D.* (2020) The Zscan4-Tet2 Transcription Nexus Regulates Metabolic Rewiring and Enhances Proteostasis to Promote Reprogramming. Cell Reports 32, 107877-107877（MCB团队，*为通讯作者）

Xia, L., Wang, X., Liu, L., Fu, J., Xiao, W., Liang, Q., Han, X., Huang, S., Sun, L., Gao, Y., Zhang, C., Yang, L., Wang, L., Qian, L.*, and Zhou, Y.* (2020) Lnc-BAZ2B promotes M2 macrophage activation and inflammation in asthmatic children through stabilizing BAZ2B pre-mRNA. Journal of Allergy and Clinical Immunology（周玉峰课题组，*为通讯作者）

Liu, H. Y., Liu, Y. Y., Yang, F., Zhang, L., Zhang, F. L., Hu, X., Shao, Z. M.*, and Li, D. Q.* (2020) Acetylation of MORC2 by NAT10 regulates cell-cycle checkpoint control and resistance to DNA-damaging chemotherapy and radiotherapy in breast cancer. Nucleic Acids Research 48, 3638-3656（李大强课题组，*为通讯作者）

Sun, W., Zhang, X., Chen, D.*, and Murchie, A. I.* (2020) Interactions between the 5′ UTR mRNA of the spe2 gene and spermidine regulate translation in S. pombe. RNA 26, 137-149（Alastair Murchie/陈东戎团队，*为通讯作者）

Zhang, X., Sun, W., Chen, D.*, and Murchie, A. I.* (2020) Interactions between SAM and the 5′ UTR mRNA of the sam1 gene regulate translation in S. pombe. RNA 26, 150-161（Alastair Murchie/陈东戎团队，*为通讯作者）

Zhang J, Liu G, Sun W, Chen, D.*, and Murchie, A. I.* The effects of aminoglycoside antibiotics on twister ribozyme cleavage. FEBS J. 2020 Aug 13（Alastair Murchie/陈东戎团队，*为通讯作者）