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2.Chen, X., Yin, X., Li, J., Wu, Z., Qi, Y., Wang, X., Liu, W., and Xu, Y.*(2021) Structures of the human Mediator and Mediator-bound preinitiation complex. Science, eabg0635（徐彦辉课题组，*为通讯作者）

3.Xu, W., Li, J., He, C., Wen, J., Ma, H., Rong, B., Diao, J., Wang, L., Wang, J., Wu, F., Tan, L., Shi, Y. G., Shi, Y.*, and Shen, H.* (2021) METTL3 regulates heterochromatin in mouse embryonic stem cells. Nature（沈宏杰团队，*为通讯作者）

4.Han, L., Qu, Q., Aydin, D., Panova, O., Robertson, M. J., Xu, Y., Dror, R. O., Skiniotis, G., and Feng, L. * (2021) Structure and mechanism of the SGLT family of glucose transporters. Nature（屈前辉博士为共同第一作者，*为通讯作者）

5.Jiang, H., Gao, Y., Zhang, L., Chen, D.*, Gan, J.*, and Murchie, A. I. H.* (2021) The identification and characterization of a selected SAM-dependent methyltransferase ribozyme that is present in natural sequences. Nature Catalysis 4, 872-881（Murchie, A. I. H./陈东戎课题组，*为通讯作者）

6.Yang, Y., Wu, Z., Wang, L., Zhou, K., Xia, K., Xiong, Q., Liu, L., Zhang, Z., Chapman, E. R., Xiong, Y., Melia, T. J., Karatekin, E., Gu, H.*, and Lin, C.* (2021) Sorting sub-150-nm liposomes of distinct sizes by DNA-brick-assisted centrifugation. Nature Chemistry（顾宏周课题组，*为通讯作者）

7.Jia Y, Chen L, Liu J, Li W, Gu H.* (2021) DNA-catalyzed efficient production of single-stranded DNA nanostructures. Chem（顾宏周课题组，*为通讯作者）

8.Wang, Y., Tian, Q., Hao, Y., Yao, W., Lu, J., Chen, C., Chen, X., Lin, Y., Huang, Q., Xu, L., Hu, J., Lei, S., Wei, Z., Luo, Y., Li, Z., Hu, L., Tang, J., Wu, Q., Zhou, X., Wu, Y., Yin, Z. *, Xu, J. *, and Ye, L. * (2021) The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4+ T cells by preventing ferroptosis. Nature Immunology（徐建青课题组，*为通讯作者）

9.Hu, S., Peng, L., Xu, C., Wang, Z., Song, A., and Chen, F. X.* (2021) SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape. Molecular Cell （陈飞课题组，*为通讯作者）

10.Li, L., Yu, Z., Zhao, D., Ren, Y., Hou, H., and Xu, Y.* (2021) Structure of human RNA polymerase III elongation complex. Cell Research（徐彦辉课题组，*为通讯作者）

11.Gu, Y., Cao, J., Zhang, X., Gao, H., Wang, Y., Wang, J., He, J., Jiang, X., Zhang, J., Shen, G., Yang, J., Zheng, X., Hu, G., Zhu, Y., Du, S., Zhu, Y., Zhang, R., Xu, J., Lan, F., Qu, D., Xu, G., Zhao, Y.*, Gao, D.*, Xie, Y.*, Luo, M.*, and Lu, Z.* (2021) Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2. Cell Research （卢智刚/罗敏课题组，*为通讯作者）

12.Xu, X., Ding, G., Liu, C., Ding, Y., Chen, X., Huang, X., Zhang, C.-S., Lu, S., Zhang, Y., Huang, Y., Chen, Z., Wei, W., Liao, L., Lin, S.-H., Li, J., Liu, W., Li, J., Lin, S.-C., Ma, X.*, and Wong, J.* (2021) Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function. Cell Research （丁广进博士为共同第一作者，*为通讯作者）

13.Shi, J., Zhang, Y., Tan, D., Zhang, X., Yan, M., Zhang, Y., Franklin, R., Shahbazi, M., Mackinlay, K., Liu, S., Kuhle, B., James, E. R., Zhang, L., Qu, Y., Zhai, Q., Zhao, W., Zhao, L., Zhou, C., Gu, W., Murn, J., Guo, J., Carrell, D. T., Wang, Y., Chen, X., Cairns, B. R., Yang, X.-l., Schimmel, P., Zernicka-Goetz, M., Cheloufi, S., Zhang, Y., Zhou, T., and Chen, Q. (2021) PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications. Nature Cell Biology（闫孟红博士为共同第一作者）

14.Wang,Y.-P.,Sharda, A., Xu, S.-N., van Gastel, N., Man, C. H., Choi, U., Leong, W. Z., Li, X., and Scadden, D. T. (2021) Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis. Cell Metabolism（王义平博士为第一作者）

15.Zeng, W.-F.*, Cao, W.-Q., Liu, M.-Q., He, S.-M., and Yang, P.-Y. (2021) Precise, fast and comprehensive analysis of intact glycopeptides and modified glycans with pGlyco3. Nature Methods （曹纬倩博士为共同第一作者）

16.Tsutsumi, N.#, Qu, Q.#, Mavri, M., Baggesen, M. S., Maeda, S., Waghray, D., Berg, C., Kobilka, B. K., Rosenkilde, M. M., Skiniotis, G., and Garcia, K. C. (2021) Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1.Immunity（屈前辉博士为共同第一作者）

17.Shi, H., Gao, Y., Dong, Z., Yang, J. e., Gao, R., Li, X., Zhang, S., Ma, L., Sun, X., Wang, Z., Zhang, F., Hu, K., Sun, A. *, and Ge, J. * (2021) GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury. Circulation Research 129, 383-396（葛均波课题组，*为通讯作者）

18.Zhang, J.-J., Fan, T.-T., Mao, Y.-Z., Hou, J.-L., Wang, M., Zhang, M., Lin, Y., Zhang, L., Yan, G.-Q., An, Y.-P., Yao, J., Zhang, C., Lin, P.-C., Yuan, Y.-Y., Zhao, J.-Y., Xu, W.*, and Zhao, S.-M.* (2021) Nuclear dihydroxyacetone phosphate signals nutrient sufficiency and cell cycle phase to global histone acetylation. Nature Metabolism（徐薇课题组，*为通讯作者）

19.Yang, H.*, Yu, Z., Chen, X., Li, J., Li, N., Cheng, J., Gao, N., Yuan, H.-X., Ye, D., Guan, K.-L., and Xu, Y.* Structural insights into TSC complex assembly and GAP activity on Rheb. Nature Communications 12, 339 (2021).（徐彦辉课题组，*为通讯作者）

20.Yang, Y., Yan, G., Kong, S., Wu, M., Yang, P., Cao, W.*, and Qiao, L.* (2021) GproDIA enables data-independent acquisition glycoproteomics with comprehensive statistical control. Nature Communications 12, 6073（乔亮/曹纬倩课题组，*为通讯作者）

21.Hou, H., Li, Y., Wang, M., Liu, A., Yu, Z., Chen, K., Zhao, D., and Xu, Y.* (2021) Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine. Nature Communications 12, 6135（徐彦辉课题组，*为通讯作者）

22.Xu, J., Yang, X., Deng, Q., Yang, C., Wang, D., Jiang, G., Yao, X., He, X., Ding, J., Qiang, J., Tu, J., zhang, R., Lei, Q.-Y., Shao, Z.-m., Bian, X.*, Hu, R.*, Zhang, L.*, and Liu, S.* (2021) TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer. Nature Communications 12, 4413（柳素玲课题组，*为通讯作者）

23.Chen, C., Hao, X., Lai, X., Liu, L., Zhu, J., Shao, H., Huang, D., Gu, H., Zhang, T., Yu, Z., Xie, L., Zhang, X., Yang, Y., Xu, J.*, Zhao, Y.*, Lu, Z.*, and Zheng, J.* (2021) Oxidative phosphorylation enhances the leukemogenic capacity and resistance to chemotherapy of B cell acute lymphoblastic leukemia. Science Advances 7, eabd6280（卢智刚课题组，*为通讯作者）

24.Zhang, H., Qin, Z., Yue, X., Liu, Y., Sun, X., Feng, J., Xu, Z., Zhao, J., Li, K., Qiu, J., Yang, W.*, He, F.*, and Ding, C.* (2021) Proteome-wide profiling of transcriptional machinery on accessible chromatin with biotinylated transposons. Science Advances 7, eabh1022（贺福初/丁琛团队，*为通讯作者）

25.Zhao, Y., Du, X., Duan, Y., Pan, X., Sun, Y., You, T., Han, L., Jin, Z., Shang, W., Yu, J., Guo, H., Liu, Q., Wu, Y., Peng, C., Wang, J., Zhu, C., Yang, X., Yang, K., Lei, Y., Guddat, L. W., Xu, W., Xiao, G., Sun, L.*, Zhang, L.*, Rao, Z.*, and Yang, H.* (2021) High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors. Protein & Cell（孙蕾课题组，*为通讯作者）

26.Liu, Z., Xu, W., Chen, Z., Fu, W., Zhan, W., Gao, Y., Zhou, J., Zhou, Y., Wu, J., Wang, Q., Zhang, X., Hao, A., Wu, W., Zhang, Q., Li, Y., Fan, K., Chen, R., Jiang, Q., Mayer, C. T., Schoofs, T., Xie, Y., Jiang, S., Wen, Y., Yuan, Z.*, Wang, K.*, Lu, L.*, Sun, L.*, and Wang, Q.* (2021) An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope. Protein & Cell （孙蕾课题组，陈振国课题组，*为通讯作者）

27.Li, J.-T., Li, K.-Y., Su, Y., Shen, Y., Lei, M.-Z., Zhang, F., Yin, M., Chen, Z.-J., Wen, W.-Y., Hu, W.-G., Su, D. *, Qu, J. *, and Lei, Q.-Y. * (2021) Diet high in branched-chain amino acid promotes PDAC development by USP1-mediated BCAT2 stabilization. National Science Review（雷群英课题组，*为通讯作者）

28.Yang, L., Yan, X., Chen, J., Zhan, Q., Hua, Y., Xu, S., Li, Z., Wang, Z., Dong, Y., Zuo, D., Xue, M., Tang, Y., Herschman, H. R., Lu, S.*, Shi, Q.*, and Wei, W.* (2021) Hexokinase 2 discerns a novel circulating tumor cell population associated with poor prognosis in lung cancer patients. PNAS 118, e2012228118（施奇惠课题组，*为通讯作者）

29.Chen, Y., Hao, Q., Wang, S., Cao, M., Huang, Y., Weng, X., Wang, J., Zhang, Z., He, X., Lu, H., and Zhou, X.* (2021) Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP. PNAS 118, e2026813118（周祥课题组，*为通讯作者）

30.Chen, J., Fan, J., Chen, Z., Zhang, M., Peng, H., Liu, J., Ding, L., Liu, M., Zhao, C., Zhao, P., Zhang, S*., Zhang, X*., and Xu, J*. (2021) Nonmuscle myosin heavy chain IIA facilitates SARS-CoV-2 infection in human pulmonary cells. PNAS 118, e2111011118（徐建青/张晓燕团队，*为通讯作者）

31.Liu, C., Qiang, J., Deng, Q., Xia, J., Deng, L., Zhou, L., Wang, D., He, X., Liu, Y., Zhao, B., Lv, J., Yu, Z., Lei, Q.-Y., Shao, Z.-M., Zhang, X.-Y., Zhang, L., and Liu, S. * (2021) ALDH1A1 Activity in Tumor-Initiating Cells Remodels Myeloid-Derived Suppressor Cells to Promote Breast Cancer Progression. Cancer Research. 81, 5919-5934（柳素玲课题组，*为通讯作者）

32.Zhang, C., Li, Q., Xu, T., Li, W., He, Y., and Gu, H.*(2021) New DNA-hydrolyzing DNAs isolated from an ssDNA library carrying a terminal hybridization stem. Nucleic Acids Research（顾宏周课题组，*为通讯作者）

33.Liang, Y., Lu, Q., Li, W., Zhang, D., Zhang, F., Zou, Q., Chen, L., Tong, Y., Liu, M., Wang, S., Li, W., Ren, X., Xu, P., Yang, Z., Dong, S., Zhang, B., Huang, Y., Li, D.*, Wang, H.*, and Yu, W.* (2021) Reactivation of tumour suppressor in breast cancer by enhancer switching through NamiRNA network. Nucleic Acids Research（于文强课题组，*为通讯作者）

34.Liu, G., Jiang, H., Sun, W., Zhang, J., Chen, D.*, and Murchie, A. I. H.* (2021) The function of twister ribozyme variants in non-LTR retrotransposition in Schistosoma mansoni. Nucleic Acids Research 49, 10573-10588（Murchie, A. I. H./陈东戎课题组，*为通讯作者）

35.Niu, C., Wang, S., Guo, J., Wei, X., Jia, M., Chen, Z., Gong, W., Qin, Y., Wang, X., Zhi, X., Lu, M., Chen, S., Gu, M., Zhang, J., Han, J.-D. J., Lan, F.*, and Meng, D*. (2021) BACH1 recruits NANOG and histone H3 lysine 4 methyltransferase MLL/SET1 complexes to regulate enhancer–promoter activity and maintains pluripotency. Nucleic Acids Research （蓝斐课题组，*为通讯作者）

36.Li, Q., Lai, H., Li, Y., Chen, B., Chen, S., Li, Y., Huang, Z., Meng, Z., Wang, P., Hu, Z.*, and Huang, S.* (2021) RJunBase: a database of RNA splice junctions in human normal and cancerous tissues. Nucleic Acids Research 49, D201-D211（黄胜林课题组，*为通讯作者）

37.An, J., Yin, M., Yin, J., Wu, S., Selby, C. P., Yang, Y., Sancar, A., Xu, G.-L., Qian, M.*, and Hu, J.* (2021) Genome-wide analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine at single-nucleotide resolution unveils reduced occurrence of oxidative damage at G-quadruplex sites. Nucleic Acids Research（胡晋川课题组、钱茂祥课题组，*为通讯作者）

38.Yang, L., Fu, J., Han, X., Zhang, C., Xia, L., Zhu, R., Huang, S., Xiao, W., Yu, H., Gao, Y., Liang, Q., Li, W. *, and Zhou, Y. * (2021) Hsa_circ_0004287 inhibits macrophage-mediated inflammation in an N6-methyladenosine-dependent manner in atopic dermatitis and psoriasis. Journal of Allergy and Clinical Immunology（周玉峰课题组、钱茂祥课题组，*为通讯作者）

39.Li, Y., Chen, B., Zhao, J., Li, Q., Chen, S., Guo, T., Li, Y., Lai, H., Chen, Z., Meng, Z., Guo, W.*, He, X.*, and Huang, S.*（2021）HNRNPL Circularizes ARHGAP35 to Produce an Oncogenic Protein. Advanced Science n/a, 2001701（黄胜林课题组，*为通讯作者）

40.Huang, R., Zhang, X., Li, W., Shang, L.*, Wang, H.*, and Zhao, Y.* (2021) Suction Cups-Inspired Adhesive Patch with Tailorable Patterns for Versatile Wound Healing. Advanced Science, e2100201-e2100201（商珞然课题组，*为通讯作者）

41.Zhao, C., Cai, L., Nie, M., Shang, L. *, Wang, Y. *, and Zhao, Y. * (2021) Cheerios Effect Inspired Microbubbles as Suspended and Adhered Oral Delivery Systems. Advanced Science 8, 2004184（商珞然课题组，*为通讯作者）

42.Zhao, D., Liu, W., Chen, K., Wu, Z., Yang, H.*, and Xu, Y.* (2021) Structure of the human RNA polymerase I elongation complex. Cell Discovery 7, 97（徐彦辉课题组，*为通讯作者）

43.Liang, L., Huan, L., Wang, J., Wu, Y., Huang, S., and He, X. * (2021) LncRNA RP11-295G20.2 regulates hepatocellular carcinoma cell growth and autophagy by targeting PTEN to lysosomal degradation. Cell Discovery 7, 118（何祥火课题组，*为通讯作者）

44.Wang, Y., Zhu, Y., Gu, Y., Ma, M., Wang, Y., Qi, S., Zeng, Y., Zhu, R., Wang, X., Yu, P., Xu, J., Shu, Y., and Yu, F.-X.* (2021) Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis. Cell Reports 36（余发星课题组，*为通讯作者）

45.Mieradilijiang, A., Zhu, S., Yan, S., Xu, K., Zhang, J., Luo, S., Ma, W., Alam, M. F., Tang, Y., Huang, H., Chen, N., Wang, L., Yan, G., Li, J., Lai, H., Wang, C.*, Zhu, K.*, and Zhang, W.* (2021) Aorta smooth muscle-on-a-chip reveals impaired mitochondrial dynamics as a therapeutic target for aortic aneurysm in bicuspid aortic valve disease. eLife 10, e69310（张炜佳课题组，*为通讯作者）

46.Huang, H., Lin, Y., Ma, W., Liu, J., Han, J., Hu, X., Tang, M., Yan, S., Abudupataer, M., Zhang, C., Gao, Q., and Zhang, W*. (2021) A pre-screening strategy to assess resected tumor margins by imaging cytoplasmic viscosity and hypoxia. eLife 10, e70471（张炜佳课题组，*为通讯作者）

47.Wang, Q., Song, Y., Chen, J., Li, Q., Gao, J., Tan, H., Zhu, Y., Wang, Z., Li, M., Yang, H., Zhang, N., Li, X., Qian, J., Pang, Z., Huang, Z. *, and Ge, J.* (2021) Direct in vivo reprogramming with non-viral sequential targeting nanoparticles promotes cardiac regeneration. Biomaterials 276, 121028（葛均波课题组，*为通讯作者）

48.Wei, Z., Chen, Z., Zhao, Y., Fan, F., Xiong, W., Song, S., Yin, Y., Hu, J., Yang, K., Yang, L., Xu, B. *, and Ge, J.* (2021) Mononuclear phagocyte system blockade using extracellular vesicles modified with CD47 on membrane surface for myocardial infarction reperfusion injury treatment. Biomaterials 275, 121000（葛均波课题组，*为通讯作者）

49.Shao, C., Chi, J., Chen, Z., Sun, L., Shang, L. *, Zhao, Y. *, and Ye, F. * (2021) Nano-imprinted anisotropic structural color graphene films for cardiomyocytes dynamic displaying. Materials Today 51, 117-125（商珞然课题组，*为通讯作者）

50.Zhang, D., Cai, L., Wei, X., Wang, Y., Shang, L. *, Sun, L. *, and Zhao, Y. * (2021) Multiplexed CRISPR/Cas9 quantifications based on bioinspired photonic barcodes. Nano Today 40, 101268（商珞然课题组，*为通讯作者）

51.Zhang, Z., Chen, Z., Wang, Y., Zhao, Y. *, and Shang, L. * Cholesteric Cellulose Liquid Crystals with Multifunctional Structural Colors. Advanced Functional Materials n/a, 2107242（商珞然课题组，*为通讯作者）

52.Xu, F., Li, J., Ni, M., Cheng, J., Zhao, H., Wang, S., Zhou, X.*, and Wu, X.* (2021) FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2. Molecular Cancer 20, 45（周祥课题组，*为通讯作者）

53.Huang, W., Li, N., Zhang, Y., Wang, X., Yin, M., and Lei, Q.-Y. *(2021) AHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner. Autophagy, 1-11（雷群英课题组，*为通讯作者）

54.Chen, T., Ding, X., Liao, Q., Gao, N., Chen, Y., Zhao, C.*, Zhang, X.*, and Xu, J.* (2021) IL-21 arming potentiates the anti-tumor activity of an oncolytic vaccinia virus in monotherapy and combination therapy. Journal for ImmunoTherapy of Cancer 9,（徐建青/张晓燕课题组，*为通讯作者）

55.Li, C., Chi, H., Deng, S., Wang, H., Yao, H., Wang, Y., Chen, D., Guo, X., Fang, J.-Y., He, F., and Xu, J.* (2021) THADA drives Golgi residency and upregulation of PD-L1 in cancer cells and provides promising target for immunotherapy. Journal for ImmunoTherapy of Cancer 9, e002443（许杰课题组，*为通讯作者）

56.He, H., Liao, Q., Zhao, C., Zhu, C., Feng, M., Liu, Z., Jiang, L., Zhang, L., Ding, X., Yuan, M*., Zhang, X.*, and Xu, J.* (2021) Conditioned CAR-T cells by hypoxia-inducible transcription amplification (HiTA) system significantly enhances systemic safety and retains antitumor efficacy. Journal for ImmunoTherapy of Cancer 9, e002755（徐建青课题组，张晓燕课题组，*为通讯作者）

57.Li C, Yao H, Wang H, Fang JY, Xu J*. Repurposing screen identifies Amlodipine as an inducer of PD-L1 degradation and antitumor immunity. Oncogene. 2021 Feb;40(6):1128-1146（许杰课题组，*为通讯作者）

58.Hao, Q., Chen, J., Liao, J., Huang, Y., Gan, Y., Larisch, S., Zeng, S. X., Lu, H.*, and Zhou, X.* (2021) p53 induces ARTS to promote mitochondrial apoptosis. Cell Death & Disease 12, 204（Lu Hua/周祥课题组，*为通讯作者）

59.Zou, Y., Pan, L., Shen, Y., Wang, X., Huang, C., Wang, H., Jin, X., Yin, C., Wang, Y., Jia, J., Qian, J., Zou, Y. *, Gong, H. *, and Ge, J. * (2021) Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload. Cell Death & Disease 12, 877（葛均波课题组，*为通讯作者）

60. Jiang, G., Tu, J., Zhou, L., Dong, M., Fan, J., Chang, Z., Zhang, L., Bian, X., and Liu, S.* (2021) Single-cell transcriptomics reveal the heterogeneity and dynamic of cancer stem-like cells during breast tumor progression. Cell Death & Disease 12, 979（柳素玲课题组，*为通讯作者）

61.Bao, R., Meng, Y., Zhang, H., Yang, C., Li, W., Zhang, C., Zhang, J., Sun, R., Li, Z., Jiang, W., Zhang, C., Zhang, C. *, Yuan, H.-X., and Dang, Y. ** (2021) Elaiophylin reduces body weight and lowers glucose levels in obese mice by activating AMPK. Cell Death & Disease 12, 972（袁海心课题组，*为通讯作者）

62.Xue, P., Huang, S., Han, X., Zhang, C., Yang, L., Xiao, W., Fu, J., Li, H.*, and Zhou, Y.* (2021) Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2. Cell Death & Differentiation （周玉峰课题组，*为通讯作者）

63.Li, H.-Y., Yin, F.-F., Li, X.-Y., Jia, W.-N., Ding, J., Zhang, L., Wang, Z.-H., Hu, Q.-Q., Zuo, J.-L., Jia, H.-L., Wang, L.-H., Fan, C.-H.*, Gu, H.-Z.*, and Wu, J.* (2021) Novel aptasensor-based assay of sonic hedgehog ligand for detection of portal vein invasion of hepatocellular carcinoma. Biosensors & Bioelectronics 174（顾宏周课题组，*为通讯作者）

64.Kong, S., Zhang, Q., Yang, L., Huang, Y., Liu, M., Yan, G., Zhao, H., Wu, M., Zhang, X., Yang, P. *, and Cao, W. * (2021) Effective Enrichment Strategy Using Boronic Acid-Functionalized Mesoporous Graphene–Silica Composites for Intact N- and O-Linked Glycopeptide Analysis in Human Serum. Analytical Chemistry 93, 6682-6691（杨芃原课题组，*为通讯作者）

65.Shen, F., Xiong, Y., Zhang, L., Li, H., Zhao, H., Liu, X.*, and Yang, P.* (2021) Rapid Sample Preparation Workflow for Serum Sample Analysis with Different Mass Spectrometry Acquisition Strategies. Analytical Chemistry 93, 1578-1585（杨芃原课题组，*为通讯作者）

66.Huang, Y., Zhang, Q., Yang, L., Lin, L., Xie, J., Yao, J., Zhou, X., Zhang, L., Shen, H. *, and Yang, P. * (2021) Puromycin-Modified Silica Microsphere-Based Nascent Proteomics Method for Rapid and Deep Nascent Proteome Profile. Analytical Chemistry 93, 6403-6413（杨芃原课题组，*为通讯作者）

67.Wu, L., Fang, C., Zhang, L., Yuan, W., Yu, X.*, and Lu, H.* (2021) Integrated Strategy for Discovery and Validation of Glycated Candidate Biomarkers for Hemodialysis Patients with Cardiovascular Complications. Analytical Chemistry（陆豪杰课题组，*为通讯作者）

68.Cheng, M., Shu, H., Peng, Y., Feng, X., Yan, G., Zhang, L., Yao, J., Bao, H., and Lu, H.* (2021) Specific Analysis of α-2,3-Sialylated N-Glycan Linkage Isomers by Microchip Capillary Electrophoresis–Mass Spectrometry. Analytical Chemistry（陆豪杰课题组，*为通讯作者）

69.Wang, Z., Zhang, L., Yuan, W., Zhang, Y. *, and Lu, H. * (2021) SAPT, a Fast and Efficient Approach for Simultaneous Profiling of Protein N- and C-Terminome. Analytical Chemistry 93, 10553-10560（陆豪杰课题组，*为通讯作者）

70.Shao, Y., Bao, H., Ma, L., Yuan, W., Zhang, L., Yao, J., Meng, P., Peng, Y., Zhang, S., Cao, T., and Lu, H.* (2021) Enhancing Comprehensive Analysis of Newly Synthesized Proteins Based on Cleavable Bioorthogonal Tagging. Analytical Chemistry（陆豪杰课题组，*为通讯作者）

71.Feng, X., Shu, H., Zhang, S., Peng, Y., Zhang, L., Cao, X., Wei, L. *, and Lu, H. * (2021) Relative Quantification of N-Glycopeptide Sialic Acid Linkage Isomers by Ion Mobility Mass Spectrometry. Analytical Chemistry 93, 15617-15625（陆豪杰课题组，*为通讯作者）

72.Du, X., Cheng, X., Li, W., Ge, Z., Zhong, C., Fan, C., and Gu, H.* (2021) Engineering Allosteric Ribozymes to Detect Thiamine Pyrophosphate in Whole Blood. Analytical Chemistry（顾宏周课题组，*为通讯作者）

73.Xu, T., Zhang, C., Xia, K., Li, W., Cao, Y. , and Gu, H. * (2021) Small DNAs that Bind Nickel(II) Specifically and Tightly. Analytical Chemistry 93, 14912-14917（顾宏周课题组，*为通讯作者）

74.Yang, Z., Xu, F., Li, H., and He, Y. * (2021) Beyond samples: A metric revealing more connections of gut microbiota between individuals. Computational and Structural Biotechnology Journal 19, 3930-3937（何云刚课题组，*为通讯作者）

75.Dong, J., Zhang, H., Mao, X., Zhu, J., Li, D., Fu, J., Hu, J., Wu, L., Chen, B., Sun, Y., Mu, J., Zhang, Z., Sun, X., Zhao, L., Wang, W., Wang, W., Zhou, Z., Zeng, Y., Du, J., Li, Q., He, L., Jin, L., Kuang, Y., Wang, L. *, and Sang, Q. * (2021) Novel biallelic mutations in MEI1: expanding the phenotypic spectrum to human embryonic arrest and recurrent implantation failure. Human Reproduction 36, 2371-2381（王磊/桑庆团队，*为通讯作者）

76.Wang, W., Wang, W., Xu, Y., Shi, J., Fu, J., Chen, B., Mu, J., Zhang, Z., Zhao, L., Lin, J., Du, J., Li, Q., He, L., Jin, L., Sun, X. *, Wang, L. *, and Sang, Q. * (2021) FBXO43 variants in patients with female infertility characterized by early embryonic arrest. Human Reproduction 36, 2392-2402（王磊/桑庆团队，*为通讯作者）

77.Yang, Z.*, Xu, F., Wang, H., Teschendorff, A. E., Xie, F., and He, Y.* (2021) Pan-cancer characterization of long non-coding RNA and DNA methylation mediated transcriptional dysregulation. EBioMedicine 68, 103399（何云刚课题组，*为通讯作者）

78.Luo, Y., Wan, G., Zhang, X., Zhou, X., Wang, Q., Fan, J., Cai, H., Ma, L., Wu, H., Qu, Q.*, Cong, Y.*, Zhao, Y.*, and Li, D.* (2021) Cryo-EM study of patched in lipid nanodisc suggests a structural basis for its clustering in caveolae. Structure（屈前辉课题组，*为通讯作者）

79.Li, Y., Li, Y., Yu, S., Qian, L., Chen, K., Lai, H., Zhang, H., Li, Y., Zhang, Y., Gu, S., Meng, Z., Huang, S. *, and Wang, P. * (2021) Circulating EVs long RNA-based subtyping and deconvolution enable prediction of immunogenic signatures and clinical outcome for PDAC. Molecular Therapy - Nucleic Acids 26, 488-501（黄胜林课题组，*为通讯作者）

80.Huang, J., Wu, M., Zhang, Y., Kong, S., Liu, M., Jiang, B., Yang, P. *, and Cao, W. * (2021) OGP: A Repository of Experimentally Characterized O-Glycoproteins to Facilitate Studies on O-Glycosylation. Genomics, Proteomics & Bioinformatics（杨芃原课题组，*为通讯作者）

81.Hao, Q., Lu, H., and Zhou, X. * (2021) A potential synthetic lethal strategy with PARP inhibitors: perspective on ‘Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP’. Journal of Molecular Cell Biology 13, 690-692（周祥课题组，*为通讯作者）

82.Huang, C., Hao, Q., Shi, G., Zhou, X. *, and Zhang, Y. (2020) BCL7C suppresses ovarian cancer growth by inactivating mutant p53. Journal of Molecular Cell Biology 13, 141-150（周祥课题组，*为通讯作者）

83.Cao, K., Wang, X., Peng, H., Ding, L., Wang, X., Hu, Y., Dong, L., Yang, T., Hong, X., Xing, M., Li, D., Zhu, C., He, X., Zhao, C., Zhao, P. *, Zhou, D. *, Zhang, X. *, and Xu, J. * A Single Vaccine Protects against SARS-CoV-2 and Influenza Virus in Mice. Journal of Virology 0, JVI.01578-01521（徐建青/张晓燕课题组，*为通讯作者）

84.Dong, S., Lu, Q.*, Xu, P., Chen, L., Duan, X., Mao, Z., Zhang, B., Sui, L.*, Wang, Y.*, and Yu, W.* (2021) Hypermethylated PCDHGB7 as a universal cancer only marker and its application in early cervical cancer screening. Clinical and Translational Medicine 11, e457（于文强课题组，*为通讯作者）

85.Zhang, W., Zhang, X., Huang, S., Chen, J., Ding, P., Wang, Q., Li, L., Lv, X., Li, L., Zhang, P., Zhou, D., Wen, W., Wang, Y., Lei, Q.-Y., Wu, J., and Hu, W.* (2021) FOXM1D potentiates PKM2-mediated tumor glycolysis and angiogenesis. Molecular Oncology 15, 1466-1485（胡维国课题组，*为通讯作者）

86.Sun, X. *, Gao, R., Li, W., Zhao, Y., Yang, H., Chen, H., Jiang, H., Dong, Z., Hu, J., Liu, J., Zou, Y., Sun, A. *, and Ge, J. * (2021) Alda-1 treatment promotes the therapeutic effect of mitochondrial transplantation for myocardial ischemia-reperfusion injury. Bioactive Materials 6, 2058-2069（葛均波课题组，*为通讯作者）

87.Hao, Q., Li, J., Zhang, Q., Xu, F., Xie, B., Lu, H., Wu, X. *, and Zhou, X. * (2021) Single-cell transcriptomes reveal heterogeneity of high-grade serous ovarian carcinoma. Clinical and Translational Medicine 11, e500（周祥课题组，*为通讯作者）

88.Li, C., Liang, W., He, Y., Zhao, X., Qian, J., Li, Z., Jiang, C., Zheng, Q., Fu, X., Zhang, W., Liu, H., Sun, X., Qian, M. *, and Zhang, H. * (2021) Inherited GATA3 variant associated with positive minimal residual disease in childhood B-cell acute lymphoblastic leukemia via asparaginase resistance. Clinical and Translational Medicine 11, e507（钱茂祥课题组，*为通讯作者）

89.Yan, S., Wang, S., Hao, Z., Liu, M., Miao, C., Alam, M. F., Bai, R., Li, L., Luo, Y., Liu, T., Lin, B., Zhang, W. *, and Lu, Y. * (2021) Rapid prototyping of PDMS microdevices via µPLAT on nonplanar surfaces with flexible hollow-out mask. Biofabrication 13, 035003（张炜佳课题组，*为通讯作者）

90.Qi, Z., Xue, Q., Wang, H., Cao, B., Su, Y., Xing, Q. *, and Yang, J.-J. * (2021) Serum CD203c+ Extracellular Vesicle Serves as a Novel Diagnostic and Prognostic Biomarker for Succinylated Gelatin Induced Perioperative Hypersensitive Reaction. Frontiers in Immunology 12（邢清和课题组，*为通讯作者）

91.Zhu, L., Qiu, C., Dai, L., Zhang, L., Feng, M., Yang, Y., Qiu, C., Zhang, A., Huang, J., Wang, Y., Wan, Y., Zhao, C., Wu, H., Lyu, J., Zhang, X. *, and Xu, J. * (2021) Hsa-miR-31 Governs T-Cell Homeostasis in HIV Protection via IFN-γ-Stat1-T-Bet Axis. Frontiers in Immunology 12（徐建青/张晓燕团队，*为通讯作者）

92.Zhong, Z., Nan, K., Weng, M., Yue, Y., Zhou, W., Wang, Z., Chu, Y., Liu, R. *, and Miao, C. * (2021) Pro- and Anti- Effects of Immunoglobulin A- Producing B Cell in Tumors and Its Triggers. Frontiers in Immunology 12（刘荣花课题组，*为通讯作者）

93.Yang, L., Gong, T., Shen, H., Pei, J., Zhang, L., Zhang, Q., Huang, Y., Hu, Z., Pan, Z., Yang, P., Lin, L., and Yu, H. * (2021) Precision N-Glycoproteomic Profiling of Murine Peritoneal Macrophages After Different Stimulations. Frontiers in Immunology 12（余红秀课题组，*为通讯作者）

94.Zhao, L., Guan, Y., Meng, Q., Wang, W., Wu, L., Chen, B., Hu, J., Zhu, J., Zhang, Z., Mu, J., Chen, Y., Sun, Y., Wu, T., Wang, W., Zhou, Z., Dong, J., Zeng, Y., Liu, R., Li, Q., Du, J., Kuang, Y., Sang, Q. *, and Wang, L. * (2021) Identification of Novel Mutations in CDC20: Expanding the Mutational Spectrum for Female Infertility. Frontiers in Cell and Developmental Biology 9（王磊/桑庆团队，*为通讯作者）

95.Liu, P., Liu, J.-P., Sun, S.-J., Gao, Y., Ai, Y., Chen, X., Sun, Y., Zhou, M., Liu, Y., Xiong, Y., and Yuan, H.-X. * (2021) CBFB-MYH11 Fusion Sequesters RUNX1 in Cytoplasm to Prevent DNMT3A Recruitment to Target Genes in AML. Frontiers in Cell and Developmental Biology 9（袁海心课题组，*为通讯作者）

96.Huang, Y., Xie, B., Cao, M., Lu, H., Wu, X., Hao, Q., and Zhou, X. * (2021) LncRNA RNA Component of Mitochondrial RNA-Processing Endoribonuclease Promotes AKT-Dependent Breast Cancer Growth and Migration by Trapping MicroRNA-206. Frontiers in Cell and Developmental Biology 9（周祥课题组，*为通讯作者）

97.Ding, J., Xu, J., Deng, Q., Ma, W., Zhang, R., He, X., Liu, S. *, and Zhang, L. * (2021) Knockdown of Oligosaccharyltransferase Subunit Ribophorin 1 Induces Endoplasmic-Reticulum-Stress-Dependent Cell Apoptosis in Breast Cancer. Frontiers in Oncology 11（柳素玲课题组，*为通讯作者）

98.Zhu, Y., Wang, X., Xu, Y., Chen, L., Ding, P., Chen, J. *, and Hu, W. * (2021) An Integrated Analysis of C5AR2 Related to Malignant Properties and Immune Infiltration of Breast Cancer. Frontiers in Oncology 11（胡维国课题组，*为通讯作者）

99.Li, Z., Wang, H., Dong, R., Man, J., Sun, L., Qian, X., Zhu, X., Cao, P., Yu, Y., Le, J., Fu, Y., Wang, P., Jiang, W., Shen, C., Ma, Y., Chen, L., Xu, Y., Shi, J., Zhang, H., Qian, M*., and Zhai, X. * (2021) Single-Cell RNA-seq Reveals Characteristics of Malignant Cells and Immune Microenvironment in Subcutaneous Panniculitis-Like T-Cell Lymphoma. Frontiers in Oncology 11（钱茂祥课题组，*为通讯作者）

100.Cao, X., Cao, Z., Shao, Y., Liu, C., Yan, G., Meng, X., Zhang, L., Chen, C., Huang, G., Shu, H. *, and Lu, H. * (2021) Analysis of Serum Paraoxonase 1 Using Mass Spectrometry and Lectin Immunoassay in Patients With Alpha-Fetoprotein Negative Hepatocellular Carcinoma. Frontiers in Oncology 11（陆豪杰课题组，*为通讯作者）

101.Xu, Y.-Q., Bao, Q.-Y., Yu, S.-X., Liu, Q., Xie, Y., Li, X., Liu, Y.-J. *, and Shen, Y.-H. * (2021) A Novel Microfluidic Chip for Fast, Sensitive Quantification of Plasma Extracellular Vesicles as Biomarkers in Patients With Osteosarcoma. Frontiers in Oncology 11（刘妍君课题组，*为通讯作者）

102.Xu, J., Ren, Z., Cao, K., Li, X., Yang, J., Luo, X., Zhu, L., Wang, X., Ding, L., Liang, J., Jin, D., Yuan, T., Li, L., and Xu, J. * (2021) Boosting Vaccine-Elicited Respiratory Mucosal and Systemic COVID-19 Immunity in Mice With the Oral Lactobacillus plantarum. Frontiers in Nutrition 8（徐建青课题组，*为通讯作者）

103.Peng, Y., Gu, B., Sun, Z., Li, Y., Zhang, Y., and Lu, H. * (2021) Linkage-selective derivatization for glycosylation site- and glycoform-specific characterization of sialic acid isomers using mass spectrometry. Chemical Communications 57, 9590-9593（陆豪杰课题组，*为通讯作者）

104.Sun, Z., Ji, G., Wang, G., Wei, L., Zhang, Y. *, and Lu, H. * (2021) One step carboxyl group isotopic labeling for quantitative analysis of intact N-glycopeptides by mass spectrometry. Chemical Communications 57, 4154-4157（陆豪杰课题组，*为通讯作者）

105.Zhang, S., Di, Y., Yao, J., Wang, Y., Shu, H., Yan, G., Zhang, L., and Lu, H. * (2021) Mass defect-based carbonyl activated tags (mdCATs) for multiplex data-independent acquisition proteome quantification. Chemical Communications 57, 737-740（陆豪杰课题组，*为通讯作者）

106.Fang, J., Sheng, X., Bao, H., Zhang, Y., and Lu, H. * (2021) Comparative analysis of intact glycopeptides from mannose receptor among different breast cancer subtypes using mass spectrometry. Talanta 223, 121676（陆豪杰课题组，*为通讯作者）

107.Zhu, C., Yang, S., Li, H., Wang, Y., Xiong, Y., Shen, F., Zhang, L., Yang, P., and Liu, X. * (2022) Rapid sample preparation workflow based on enzymatic nanoreactors for potential serum biomarker discovery in pancreatic cancer. Talanta 238, 123018（杨芃原课题组，*为通讯作者）

108.Mi, S., Jiang, H., Zhang, L., Xie, Z., Zhou, J., Sun, A., Jin, H. *, and Ge, J. * (2021) Regulation of Cardiac-Specific Proteins Expression by Moderate-Intensity Aerobic Exercise Training in Mice With Myocardial Infarction Induced Heart Failure Using MS-Based Proteomics. Frontiers in Cardiovascular Medicine 8（葛均波课题组，*为通讯作者）

109.Lan, W., Li, Z., Jiao, F., Wang, C., Guo, R. *, and Cao, C. * (2021) Structural Basis of RACK7 PHD Domain to Read a Pediatric Glioblastoma-Associated Histone Mutation H3.3G34R. Chinese Journal of Chemistry 39, 2433-2440（郭睿，*为通讯作者）

110.Zhang, Y., Fang, C., Bao, H., Yuan, W., and Lu, H. * (2021) Discover the Post-Translational Modification Proteome Using Mass Spectrometry. Chinese Journal of Chemistry 39, 550-558（陆豪杰课题组，*为通讯作者）

111.He, X., Ding, L., Cao, K., Peng, H., Gu, C., Li, Y., Li, D., Dong, L., Hong, X., Wang, X., Fu, M., Qiu, C., Zhu, C., Zhang, Z., Song, S., Wang, C., Jiang, Z., Xie, Y., Qi, Z., Zhao, C., Zhao, P., Zhang, X. *, and Xu, J. * (2021) A human cell-based SARS-CoV-2 vaccine elicits potent neutralizing antibody responses and protects mice from SARS-CoV-2 challenge. Emerging Microbes & Infections 10, 1555-1573（徐建青/张晓燕团队，*为通讯作者）

112.Zheng, F., Liu, G., Dang, T., Chen, Q., An, Y., Wu, M., Kong, X., Qiu, Z., and Wu, B.-L. * (2021) GABA Signaling Pathway-associated Gene PLCL1 Rare Variants May be Associated with Autism Spectrum Disorders. Neuroscience Bulletin 37, 1240-1245（吴柏林课题组，*为通讯作者）

113.Liu, J., Hao, Y., He, Y., Li, X., Sun, D.-e., Zhang, Y., Yang, P.-Y. *, and Chen, X. * (2021) Quantitative and Site-Specific Chemoproteomic Profiling of Protein O-GlcNAcylation in the Cell Cycle. ACS Chemical Biology 16, 1917-1923（杨芃原课题组，*为通讯作者

114.Yu, L., Wang, L., Tao, W., Zhang, W., Yang, S., Wang, J., Fei, J., Peng, R., Wu, Y., Zhen, X., Shao, H., Gu, W., Li, R., Wu, B.-L. *, and Wang, H. * (2021) LHCGR and ALMS1 defects likely cooperate in the development of polycystic ovary syndrome indicated by double-mutant mice. Journal of Genetics and Genomics 48, 384-395（吴柏林课题组，*为通讯作者）

115.Wang, Y., Qiao, Y., Cheng, Y., Su, Y., Song, L., Xu, Y., Li, H., Zhang, L., Song, J., Zhang, X., Wang, J., Zhu, D., Tang, T., Shang, Q., Gao, C., Wang, X., Zhu, C. *, and Xing, Q. * (2021) TEP1 is a risk gene for sporadic cerebral palsy. Journal of Genetics and Genomics（邢清和课题组，*为通讯作者）

1.Liu, Y., Sun, L., Zhang, H., Shang, L.*, and Zhao, Y.* (2021) Microfluidics for Drug Development: From Synthesis to Evaluation. Chemical Reviews （综述，商珞然课题组，*为通讯作者）

2.Yang, H., Beutler, B., and Zhang, D. * (2021) Emerging roles of spliceosome in cancer and immunity. Protein & Cell（综述，张端午课题组，*为通讯作者）

3.Li, Q., Tong, Z., Cao, Y., and Gu, H.* (2021) DNAs catalyzing DNA nanoconstruction. Chem（评述，顾宏周课题组，*为通讯作者）

4.Zhang, Z., and Shang, L. * (2021) Smart ingestible devices: Orally delivering macromolecules and beyond. Matter 4, 3379-3381（评述，商珞然课题组，*为通讯作者）

5.Zhang, R., Tu, J., and Liu, S.*(2021) Novel molecular regulators of breast cancer stem cell plasticity and heterogeneity. Seminars in Cancer Biology （综述，柳素玲课题组，*为通讯作者）

6.Yang, L., Xie, X., Tu, Z., Fu, J., Xu, D.*, and Zhou, Y*. (2021) The signal pathways and treatment of cytokine storm in COVID-19. Signal Transduction and Targeted Therapy 6, 255（综述，周玉峰课题组，*为通讯作者）

7.Wei, G., Zhang, H., Zhao, H., Wang, J., Wu, N., Li, L., Wu, J., and Zhang, D. * (2021) Emerging immune checkpoints in the tumor microenvironment: Implications for cancer immunotherapy. Cancer Letters 511, 68-76（综述，张端午课题组，*为通讯作者）

8.Li, F. *, Xu, J. *, and Liu, S. * (2021) Cancer Stem Cells and Neovascularization. Cells 10, 1070（综述，柳素玲课题组，*为通讯作者）

9.Tan, Y., Wang, M., Zhang, Y., Ge, S., Zhong, F. *, Xia, G. *, and Sun, C. * (2021) Tumor-Associated Macrophages: A Potential Target for Cancer Therapy. Frontiers in Oncology 11（综述，钟凡，*为通讯作者）

10.Cao, W. *, Liu, M., Kong, S., Wu, M., Zhang, Y., and Yang, P. * (2021) Recent Advances in Software Tools for More Generic and Precise Intact Glycopeptide Analysis. Molecular & Cellular Proteomics 20（综述，杨芃原课题组，*为通讯作者）

11.Zhang, Y., Wei, H., and Wen, W. * (2021) Phase Separation and Mechanical Forces in Regulating Asymmetric Cell Division of Neural Stem Cells. International Journal of Molecular Sciences 22, 10267（综述，温文玉课题组，*为通讯作者）

12.Liu, W., Tang, D., Xu, X.-X., Liu, Y.-J. *, and Jiu, Y. * (2021) How Physical Factors Coordinate Virus Infection: A Perspective From Mechanobiology. Frontiers in Bioengineering and Biotechnology 9（综述，刘妍君课题组，*为通讯作者）