博士,复旦特聘研究员
地址:东安路131号,上海 200032
网站:http://yang-laboratory.com;https://yanglab.github.io
邮箱:liyang_fudan@fudan.edu.cn
1.Yang L*, Wilusz JE* and Chen LL*. Biogenesis and regulatory roles of circular RNAs. AnnuRevCell DevBiol, 2022, Online ahead of print, doi: 10.1146/annurev-cellbio-120420-125117 (Review)
2.Li X#,*, Zhou L#, Gao BQ#, Li G#, Wang X#, Wang Y, Wei J, Han W, Wang Z, Li J, Gao R, Zhu J, Xu W, Wu J, Yang B, Sun X*, Yang L* and Chen J*. Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure. Nat Commun, 2022, 13: 1669
3.Gao R#, Fu ZC#, Li X#, Wang Y#, Wei J, Li G, Wang L, Wu J, Huang X*, Yang L* and Chen J*. Genomic and Transcriptomic Analyses of Prime Editing Guide RNA-Independent Off-Target Effects by Prime Editors. CRISPR J, 2022, 5: 276-293
4.Gao X#, Ma XK#, Li X, Li GW, Liu CX, Zhang J, Wang Y, Wei J, Chen J, Chen LL, Yang L*. Knockout of circRNAs by base editing back-splice sites of circularized exons. Genome Biol, 2022, 23:16
5.Wang L#, Xue W#, Zhang H#, Gao R#, Qiu H#, Wei J, Zhou L, Lei YN, Wu X, Li X, Liu C, Wu J, Chen Q, Ma H, Huang X, Cai C, Zhang Y, Yang B*, Yin H*, YangL*, Chen J*. Eliminating genome-wide and transcriptome-wide off-target mutations by base editor. Nat Cell Biol, 2021, 23: 552-563
6.Li GW#, Nan F#, Yuan GH, Liu CX, Liu X, Chen LL, Tian B, Yang L*. SCAPTURE: a deep learning-embedded pipeline that captures polyadenylation information from 3' tag-based RNA-seq of single cells. Genome Biol, 2021, 22: 221
7.Li SQ#, Li X#, Xue W#, Zhang L#, Cao SM, Lei YN, Yang LZ, Guo SK, Zhang JL, Gao X, Wei J, Li J*, Yang L*, and Chen LL*. Screening for functional circular RNAs using the CRISPR-Cas13 system. Nat Methods, 2021, 18: 51–59
·Highlighted byNat Rev Genet, 2021, 22: 68
8.Wang Y#, Gao R#, Wu J#, Xiong YC, Wei J, Zhang S, Yang B, Chen J* andYang L*. Comparison of cytosine base editors and development of the BEable-GPS database for targeting pathogenic SNVs. Genome Biol, 2019, 20: 218
9.Liu CX#, Li X#, Nan F#, Jiang S, Gao X, Guo SK, Xue W, Cui Y, Dong K, Ding H, Qu B, Shen N*, Yang L* and Chen LL*. Structure and degradation of circular RNAs regulate PKR activation in innate immunity. Cell,2019, 177: 865-880 (Featured Article)
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·Highlighted byCell, 2019, 177: 797-799
·Highlighted byScience, 2019, 364: 847
·Highlighted byNat Rev Immunol, 2019, 19: 351
·Highlighted byNat Rev Mol Cell Biol, 2019, 20: 387
·Highlighted byCell Biosci, 2019, 9: 43
·Highlighted by F1000 Prime, https://f1000.com/prime/735608202
·Highlighted byScience News Magazine, https://www.sciencenews.org/article/lack-circular-rna-may-trigger-lupus
10.WangX#, Li J#, Wang Y#, Yang B#, Wei J#, Wu J, Wang R, Huang X*, Chen J* andYang L*. Efficient base editing in methylated regions with a human APOBEC3A-Cas9 fusion. Nat Biotechnol, 2018, 36: 946-949
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·Highlighted byNat Methods, 2018, 15: 763
·Highlighted byNature Index, 2018, https://www.natureindex.com/article/10.1038/nbt.4198
11.Li X#, Wang Y#, Liu Y#, Yang B#, Wang X, Wei J, Lu Z, Zhang Y, Wu J, Huang X*, Yang L* and Chen J*. Base editing with a Cpf1-cytidine deaminase fusion. Nat Biotechnol, 2018, 36: 324-327
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·Highlighted byNat Methods, 2018, 15: 314
12.Xiang JF#, Yang Q#, Liu CX#, Wu M, Chen LL* and Yang L*. N6-methyladenosines modulate A-to-I RNA editing. Mol Cell, 2018, 69: 126-135
13.Zhang XO#, Dong R#, Zhang Y#, Zhang JL, Luo Z, Zhang J, Chen LL* and Yang L*. Diverse alternative back-splicing and alternative splicing landscape of circular RNAs. Genome Res, 2016, 26: 1277-1287
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14.Zhang XO#, Wang HB#, Zhang Y, Lu X, Chen LL* and Yang L*. Complementary sequence-mediated exon circularization.Cell, 2014,159: 134-147
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·Highlighted byCell, 2014, 159: 13-14
·Highlighted byNat Rev Genet, 2014, 15: 707
·Highlighted byF1000 Prime, https://f1000.com/prime/718882519
15.Zhang Y#, Zhang XO#, Chen T, Xiang JF, Yin QF, Xing YH, Zhu S, Yang L* and Chen LL*. Circular intronic long noncoding RNAs. Mol Cell, 2013, 51: 792-806 (Issue Highlight)
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·Highlighted by Mol Cell, 2013, 51:705-706
·Highlighted byNature China, 2013, Epub. on Oct. 2nd (doi:10.1038)
·Highlighted byInstitute for Creation Res, 2013, Epub. on Oct. 9th
·Highlight byNature, 2013, 501:464