博士,研究员,博士生导师
地址:斜土路1609号,19号楼203室,上海 200032
电话:021-64041990
传真:021-64223006
邮箱:sun.aijun@zs-hospital.sh.cn
Yang, G., X. Weng, Y. Zhao, X. Zhang, Y. Hu, X. Dai, P. Liang, P. Wang, L. Ma, X. Sun, L. Hou, H. Xu, M. Fang, Y. Li, T. Jenuwein, Y. Xu*, and A. Sun*. 2017. The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction. Nat Commun. 8:14941.
Wang, Y., X. Yan, S. Mi, Z. Li, Y. Wang, H. Zhu, X. Sun, B. Zhao, C. Zhao, Y. Zou, K. Hu, X. Ding*, A. Sun*, and J. Ge*. 2017. Naoxintong attenuates Ischaemia/reperfusion Injury through inhibiting NLRP3 inflammasome activation. J Cell Mol Med. 21:4-12.
Shen, C., C. Wang, S. Han, Z. Wang, Z. Dong, X. Zhao, P. Wang, H. Zhu, X. Sun, X. Ma, H. Zhu*, Y. Zou, K. Hu, J. Ge*, and A. Sun*. 2016. Aldehyde dehydrogenase 2 deficiency negates chronic low-to-moderate alcohol consumption-induced cardioprotecion possibly via ROS-dependent apoptosis and RIP1/RIP3/MLKL-mediated necroptosis. Biochim Biophys Acta. pii: S0925-4439(16)30298-8.
Liu, X., and A. Sun*. 2016. Aldehyde Dehydrogenase-2 Roles in Ischemic Cardiovascular Disease. Curr Drug Targets. [Epub ahead of print]
Wang, C., F. Fan, Q. Cao, C. Shen, H. Zhu, P. Wang, X. Zhao, X. Sun, Z. Dong, X. Ma, X. Liu, S. Han, C. Wu, Y. Zou, K. Hu, J. Ge*, and A. Sun*. 2016. Mitochondrial aldehyde dehydrogenase 2 deficiency aggravates energy metabolism disturbance and diastolic dysfunction in diabetic mice. J Mol Med (Berl). 94:1229-1240.
Xia, G., F. Fan, M. Liu, S. Wang, J. Wu, C. Shen, S. Han, C. Wang, J. Jia, Y. Zou, K. Hu, J. Ge*, and A. Sun*. 2016. Aldehyde dehydrogenase 2 deficiency blunts compensatory cardiac hypertrophy through modulating Akt phosphorylation early after transverse aorta constriction in mice. Biochim Biophys Acta. 1862:1587-93.
Wang, P., L. Xu, and A. Sun*. 2016. Energy Remodeling, Mitochondrial Disorder and Heart Failure. Curr Pharm Des. 22:4823-4829.
Wang, C., X. Li, C. Shen, L.L. Ma, Z. Dong, H. Zhu, P. Wang, J.B. Ge, and A. Sun*. 2016. SPECT imaging of cytochrome c in pressure overload mice hearts. RSC Advances. 6:88896-88896.
Zhao, X., C. Shen, H. Zhu, C. Wang, X. Liu, X. Sun, S. Han, P. Wang, Z. Dong, X. Ma, K. Hu, A. Sun*, and J. Ge*. 2016. Trans-Fatty Acids Aggravate Obesity, Insulin Resistance and Hepatic Steatosis in C57BL/6 Mice, Possibly by Suppressing the IRS1 Dependent Pathway. Molecules. 21(6). pii: E705.
Liu, X., X. Sun, H. Liao, Z. Dong, J. Zhao, H. Zhu, P. Wang, L. Shen, L. Xu, X. Ma, C. Shen, F. Fan, C. Wang, K. Hu, Y. Zou, J. Ge, J. Ren, and A. Sun*. 2015. Mitochondrial Aldehyde Dehydrogenase 2 Regulates Revascularization in Chronic Ischemia: Potential Impact on the Development of Coronary Collateral Circulation. Arterioscler Thromb Vasc Biol. 35:2196-206.
Shen, C., C. Wang, F. Fan, Z. Yang, Q. Cao, X. Liu, X. Sun, X. Zhao, P. Wang, X. Ma, H. Zhu, Z. Dong, Y. Zou, K. Hu, A. Sun*, and J. Ge. 2015. Acetaldehyde dehydrogenase 2 (ALDH2) deficiency exacerbates pressure overload-induced cardiac dysfunction by inhibiting Beclin-1 dependent autophagy pathway. Biochim Biophys Acta. 1852:310-8.
Wang, P., C. Shen, L. Diao, Z. Yang, F. Fan, C. Wang, X. Liu, X. Sun, Z. Dong, H. Zhu, X. Ma, Q. Cao, X. Zhao, D. Ma, Y. Zou, K. Hu, A. Sun*, and J. Ge*. 2015. Aberrant hypermethylation of aldehyde dehydrogenase 2 promoter upstream sequence in rats with experimental myocardial infarction. Biomed Res Int. 2015:503692.
Zhu, H., A. Sun*, H. Zhu, Z. Li, Z. Huang, S. Zhang, X. Ma, Y. Zou, K. Hu, and J. Ge*. 2014. Aldehyde dehydrogenase-2 is a host factor required for effective bone marrow mesenchymal stem cell therapy. Arterioscler Thromb Vasc Biol. 34:894-901.
Sun, A.*, Y. Cheng, Y. Zhang, Q. Zhang, S. Wang, S. Tian, Y. Zou, K. Hu, J. Ren, and J. Ge. 2014. Aldehyde dehydrogenase 2 ameliorates doxorubicin-induced myocardial dysfunction through detoxification of 4-HNE and suppression of autophagy. J Mol Cell Cardiol. 71:92-104.
Sun, A.*, Y. Zou*, P. Wang, D. Xu, H. Gong, S. Wang, Y. Qin, P. Zhang, Y. Chen, M. Harada, T. Isse, T. Kawamoto, H. Fan, P. Yang, H. Akazawa, T. Nagai, H. Takano, P. Ping, I. Komuro*, and J. Ge*. 2014. Mitochondrial aldehyde dehydrogenase 2 plays protective roles in heart failure after myocardial infarction via suppression of the cytosolic JNK/p53 pathway in mice. J Am Heart Assoc. 3:e000779.
Fan, F., Q. Cao, C. Wang, X. Ma, C. Shen, X. Liu, L. Bu, Y. Zou, K. Hu, A. Sun*, and J. Ge*. 2014. Impact of chronic low to moderate alcohol consumption on blood lipid and heart energy profile in acetaldehyde dehydrogenase 2-deficient mice. Acta Pharmacol Sin. 35:1015-22.
Zhang, S., X. Ma, K. Yao, H. Zhu, Z. Huang, L. Shen, J. Qian, Y. Zou, A. Sun*, and J. Ge*. 2014. Combination of CD34-positive cell subsets with infarcted myocardium-like matrix stiffness: a potential solution to cell-based cardiac repair. J Cell Mol Med. 18:1236-8.
Shen, C., L. Xu, Z. Yang, Y. Zou, K. Hu, Z. Fan, J. Ge, and A. Sun*. 2013. A1180V of cardiac sodium channel gene (SCN5A): is it a risk factor for dilated cardiomyopathy or just a common variant in Han Chinese? Dis Markers. 35:531-5.
Zhao, J., H. Zhu, S. Wang, X. Ma, X. Liu, C. Wang, H. Zhao, S. Fan, X. Jin, B. Zhao, T. Zhao, L. Jia, K. Wang, Y. Zou, K. Hu, A. Sun*, and J. Ge*. 2013. Naoxintong protects against atherosclerosis through lipid-lowering and inhibiting maturation of dendritic cells in LDL receptor knockout mice fed a high-fat diet. Curr Pharm Des. 19:5891-6.
Fan, F., A. Sun*, H. Zhao, X. Liu, W. Zhang, X. Jin, C. Wang, X. Ma, C. Shen, Y. Zou, K. Hu, and J. Ge*. 2013. MicroRNA-34a promotes cardiomyocyte apoptosis post myocardial infarction through down-regulating aldehyde dehydrogenase 2. Curr Pharm Des. 19:4865-73.