博士,教授,博士生导师,复旦大学附属妇产科医院兼职教授
地址:淞沪路2005号,生科楼C313室,上海 200433
电话:021-51630419(办公室)
传真:021-51630422
实验室主页:http://metabolism.fudan.edu.cn
1. Li, F., He, X., Ye, D., Lin, Y., Yu, H., Yao, C., Huang, L., Zhang, J., Wang, F., Xu, S., Wu, X., Liu, L., Yang, C., Shi, J., He, X., Liu, J., Qu, Y., Guo, F., Zhao, J., Xu, W., and Zhao, S*. (2015) NADP(+)-IDH Mutations Promote Hypersuccinylation that Impairs Mitochondria Respiration and Induces Apoptosis Resistance. Molecular cell 60, 661-675
2. Zhang, T., Wang, S., Lin, Y., Xu, W., Ye, D., Xiong, Y., Zhao, S.*, and Guan, K. L.* (2012) Acetylation negatively regulates glycogen phosphorylase by recruiting protein phosphatase 1. Cell metabolism 15, 75-87
3. Xu, W., Yang, H., Liu, Y., Yang, Y., Wang, P., Kim, S. H., Ito, S., Yang, C., Wang, P., Xiao, M. T., Liu, L. X., Jiang, W. Q., Liu, J., Zhang, J. Y., Wang, B., Frye, S., Zhang, Y., Xu, Y. H., Lei, Q. Y., Guan, K. L., Zhao, S. M.*, and Xiong, Y.* (2011) Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases. Cancer cell 19, 17-30
4. Jiang, W., Wang, S., Xiao, M., Lin, Y., Zhou, L., Lei, Q., Xiong, Y., Guan, K. L., and Zhao, S.* (2011) Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase. Molecular cell 43, 33-44
5. Wang, Q., Zhang, Y., Yang, C., Xiong, H., Lin, Y., Yao, J., Li, H., Xie, L., Zhao, W., Yao, Y., Ning, Z. B., Zeng, R., Xiong, Y., Guan, K. L., Zhao, S.*, and Zhao, G. P.* (2010) Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux. Science 327, 1004-1007