1.Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L*; Rao Z*; Yang H*. TMPRSS2 and glycan receptors synergistically facili-tate coronavirus entry. Cell (accepted )

2.Wang Y, Hao A, Ji P, Ma Y, Zhang Z, Chen J, Mao Q, Xiong X, Rehati P, Wang Y, Wang Y, Wen Y, Lu L, Chen Z, Zhao J*; Wu F,*; Huang J,*; Sun L*. A bispecific antibody exhibits broad neutralization against SARS-CoV-2 Omicron variants XBB.1.16, BQ.1.1 and Sarbecoviruses. Nat Commun（Accepted）

3.Hu Y, Zhang Z, Mao Q, Zhang X, Hao A, Xun Y, Wang Y, Han L, Zhan W, Liu Q, Yin Y, Peng C, Moresco EMY, Chen Z*, Beutler B*, Sun L*. Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3(KBTBD2). Nat Struct Mol Biol 2024, 31(2): 336-350.

4.Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z*, Chu H*, Sun L*, Wang P*. Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination. Cell Discov 2024, 10(1): 14.

5.Hao A, Song W, Li C, Zhang X, Tu C, Wang X, Wang P, Wu Y*, Ying T*, Sun L*. Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants. Signal Transduct Tar 2023, 8(1).

6.Wu J, Chen Z, Gao Y, Wang Z, Wang J, Chiang BY, Zhou Y, Han Y, Zhan W, Xie M, Jiang W, Zhang X, Hao A, Xia A, He J, Xue S, Mayer CT, Wu F, Wang B, Zhang L*, Sun L*, Wang Q*. Fortuitous somatic mutations during antibody evolution endow broad neutralization against SARS-CoV-2 Omicron variants. Cell Rep 2023, 42(5): 112503.

7.Wang H, Yang Q, Liu X, Xu Z, Shao M, Li D, Duan Y, Tang J, Yu X, Zhang Y, Hao A, Wang Y, Chen J, Zhu C, Guddat L, Chen H, Zhang L*, Chen X*, Jiang B*, Sun L*, Rao Z, Yang H*. Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nat Commun 2023, 14(1): 7574.

8.Ma Y, Mao Q, Wang Y, Zhang Z, Chen J, Hao A, Rehati P, Wang Y, Wen Y, Lu L, Chen Z, Zhao J*, Wu F*, Sun L*, Huang J*. A broadly neutralizing antibody inhibits SARS-CoV-2 variants through a novel mechanism of disrupting spike trimer integrity. Cell Res 2023.

9.Liu Q, Zhang X, Huang H, Chen Y, Wang F, Hao A, Zhan W, Mao Q, Hu Y, Han L, Sun Y, Zhang M, Liu Z, Li GL, Zhang W, Shu Y*, Sun L*, Chen Z*. Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger. Nat Commun 2023, 14(1): 3012.

10.Li S, Wu J, Jiang W, He H, Zhou Y, Wu W, Gao Y, Xie M, Xia A, He J, Zhang Q, Han Y, Wang N, Zhu G, Wang Q, Zhang Z, Mayer CT, Wang K, Wang X, Wang J, Chen Z*, Jiang S*, Sun L*, Xia R*, Wang Q*. Characterization of cross-reactive monoclonal antibodies against SARS-CoV-1 and SARS-CoV-2: Implication for rational design and development of pan-sarbecovirus vaccines and neutralizing antibodies. J Med Virol 2023, 95(2): e28440.

11.Han L, Chen Z, Sun L*. Expression, purification, and microscopic characterization of the tumor suppressor KLHL6. Protein Expr Purif 2023, 210: 106318.

12.Zhan W, Tian X, Zhang X, Xing S, Song W, Liu Q, Hao A, Hu Y, Zhang M, Ying T*, Chen Z*, Lan F*, Sun L*. Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer. J Virol 2022, 96(16): e0048022.

13.Li C, Zhan W, Yang Z, Tu C, Hu G, Zhang X, Song W, Du S, Zhu Y, Huang K, Kong Y, Zhang M, Mao Q, Gu X, Zhang Y, Xie Y, Deng Q, Song Y, Chen Z, Lu L, Jiang S, Wu Y*, Sun L*, Ying T*. Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody. Cell 2022, 185(8): 1389-1401 e1318.

14.Wang Y, Zhang X, Ma Y, Wang Y, Zhan W, Zheng Q, Zhang M, Ji P, Liu M, Liu Q, Sun T, Zhu T, Wen Y, Sun L*, Zhao J*, Wu F*, Chen Z*, Huang J*. Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies. Cell Discov 2022, 8(1): 104.

15.Wang Y, Zhan W, Liu J, Wang Y, Zhang X, Zhang M, Han L, Ma Y, Lu L, Wen Y, Chen Z, Zhao J*, Wu F*, Sun L*, Huang J*. A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding. Cell Res 2022, 32(9): 862-865.

16.Liu Z, Xu W, Chen Z, Fu W, Zhan W, Gao Y, Zhou J, Zhou Y, Wu J, Wang Q, Zhang X, Hao A, Wu W, Zhang Q, Li Y, Fan K, Chen R, Jiang Q, Mayer CT, Schoofs T, Xie Y, Jiang S, Wen Y, Yuan Z*, Wang K*, Lu L*, Sun L*, Wang Q*. An ultrapotent pan-beta-coronavirus lineage B (beta-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope. Protein Cell 2022, 13(9): 655-675.

17.Zhao Y, Du X, Duan Y, Pan X, Sun Y, You T, Han L, Jin Z, Shang W, Yu J, Guo H, Liu Q, Wu Y, Peng C, Wang J, Zhu C, Yang X, Yang K, Lei Y, Guddat LW, Xu W, Xiao G, Sun L*, Zhang L*, Rao Z*, Yang H*. High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors. Protein Cell 2021, 12(11): 877-888.

18.Yue T, Zhan X, Zhang D, Jain R, Wang KW, Choi JH, Misawa T, Su L, Quan J, Hildebrand S, Xu D, Li X, Turer E, Sun L, Moresco EMY, Beutler B*. SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell-mediated immunity. Science 2021, 372(6543).

19.Hu Y, Sun L*. Systematic Analysis of Structure Similarity between Zika Virus and Other Flaviviruses. ACS Infect Dis 2019, 5(7): 1070-1080.

Before 2017:

1.Chen Z, Sun L^#, Zhang Z, Fokine A, Padilla-Sanchez V, Hanein D, Jiang W, Rossmann MG*, Rao VB*. Cryo-EM structure of the bacteriophage T4 isometric head at 3.3-A resolution and its relevance to the assembly of icosahedral viruses. Proc Natl Acad Sci U S A 2017, 114(39): E8184-E8193.

2.Sirohi D, Chen Z, Sun L^#, Klose T, Pierson TC, Rossmann MG*, Kuhn RJ*. The 3.8 A resolution cryo-EM structure of Zika virus. Science 2016, 352(6284): 467-470.

3.Sun L^#, Zhang X, Gao S, Rao PA, Padilla-Sanchez V, Chen Z, Sun S, Xiang Y, Subramaniam S, Rao VB*, Rossmann MG*. Cryo-EM structure of the bacteriophage T4 portal protein assembly at near-atomic resolution. Nat Commun 2015, 6: 7548.

4.Sun L^#, Young LN, Zhang X, Boudko SP, Fokine A, Zbornik E, Roznowski AP, Molineux IJ, Rossmann MG*, Fane BA*. Icosahedral bacteriophage PhiX174 forms a tail for DNA transport during infection. Nature 2014, 505(7483): 432-435.

5.Sun L^#, Rossmann MG*, Fane BA*. High-resolution structure of a virally encoded DNA-translocating conduit and the mechanism of DNA penetration. J Virol 2014, 88(18): 10276-10279.