博士，研究员，博士生导师，复旦大学附属儿科医院兼职教授
地址：东安路131号，明道楼309室，上海 200032
电话：021-54237304（办公室）；021-5423732（实验室）
邮箱：fxyu@fudan.edu.cn
实验室主页：http://yu-lab.fudan.edu.cn
1. Li Y, Li J, Wang R, Zhang L, Fu G, Wang X, Wang Y, Fang C, Zhang D, Du D, Ma X, Pan M, Guo Q, Xu X, Hu X, Zhou Y, Mo S, Wang H, Gao J, Huang S, Liu Y, Cai S, Hua G*, Peng J*, Yu FX*. Frequent RNF43 mutation contributes to moderate activation of Wnt signaling in colorectal signet-ring cell carcinoma. Protein Cell. 2020 Feb 1. doi: 10.1007/s13238-020-00691-0.
2. Fang C, Li J, Qi S, Lei Y, Zeng Y, Yu P, Hu Z, Zhou Y, Wang Y, Dai R, Li J, Huang S, Xu P, Chen K, Ding C, Yu FX*. An alternatively transcribed TAZ variant negatively regulates JAK-STAT signaling. EMBO Rep. 2019 Jun;20(6). pii: e47227.
3. Gong R, Hong AW, Plouffe SW, Zhao B, Liu G, Yu FX*,Xu Y*, Guan KL*. Opposing roles of conventional and nove PKC in the Hippo-YAP pathway regulation. Cell Res. 2015 Aug;25(8):985-8.
4. Yu FX*, Zhao B, Guan KL*. Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer. Cell. 2015 Nov 5;163(4):811-28.
Leading Edge Review
5. Yu FX, Luo J, Mo JS, Liu G, Kim YC, Meng Z, Zhao L, Peyman G, Ouyang H, Jiang W, Zhao J, Chen X, Zhang L, Wang CY, Bastian BC, Zhang K, Guan KL. Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP. Cancer Cell. 2014 Jun 16;25(6):822-30
Preview: GANQ/11 mutations in uveal melanoma Cancer Cell
Feature: A New Therapeutic Target in Uveal Melanoma. Sci. Signal.
Fox News, Scientists discover how two gene mutations cause melanoma of the eye
6. Yu FX, Zhang Y, Park HW, Jewell JL, Chen Q, Deng Y, Pan D, Taylor SS, Lai ZC, Guan KL. Protein Kinase A activates the Hippo pathway to modulate cell proliferation and differentiation. Genes Dev. 2013 Jun 1;27(11):1223-32.
Feature: PKA Augments Hippo Signaling. Sci. Signal.
7. Yu FX, Zhao B, Panupinthu N, Jewell JL, Lian I, Wang LH, Zhao J, Yuan H, Tumaneng K, Li H, Fu XD, Mill GB, Guan KL. Regulation of the Hippo-YAP pathway by G-protein coupled receptor signaling. Cell. 2012 Aug 17;150(4):780-91.
Preview: Hippo Signaling Goes Long Range. Cell
Features: Nature Reviews Molecular Cell Biology; Sci. Signal.; Cancer Discovery
F1000, http://f1000.com/717956665
Cell, Best of 2012 in Cell
Sci. Signal, 2012 Signaling Breakthroughs of the Year
*通讯作者