课题组长余发星目前主持和参与多项国家或省部级项目，包括国家自然科学基金面上项目、优青项目，科技部重点研发项目及上海市科委项目。迄今为止，已在国内外学术刊物上发表论文50余篇，包括Cell，Molecular Cell, Cancer Cell, Genes & Development, Cell Research, EMBO Reports，Protein & Cell，Cell Reports等，论文被引用8000余次（中国高被引学者）。

1、Qi S, Zhu Y, Liu X, Li P, Wang Y, Zeng Y, Yu A, Wang Y, Sha Z, Zhong Z, Zhu R, Yuan H, Ye D, Huang S, Ling C, Xu Y, Zhou D, Zhang L, Yu, F.-X.* WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy. MolecularCell 2022 Apr 8:S1097-2765(22)00265-9.

2、Wang, Y., Zhu, Y., Gu, Y., Ma, M., Wang, Y., Qi, S., Zeng, Y., Zhu, R., Wang, X., Yu, P., Xu, J., Shu, Y., and Yu, F.-X.* Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis. Cell Reports Dec 7;14(712):eabj8393.

3、Li Y, Li J, Wang R, Zhang L, Fu G, Wang X, Wang Y, Fang C, Zhang D, Du D, Ma X, Pan M, Guo Q, Xu X, Hu X, Zhou Y, Mo S, Wang H, Gao J, Huang S, Liu Y, Cai S, Hua G*, Peng J*, Yu FX*. Frequent RNF43 mutation contributes to moderate activation of Wnt signaling in colorectal signet-ring cell carcinoma. Protein & Cell . 2020 Apr;11(4):292-298.

4、Pan, B., Yang, Y., Li, J., Wang, Y., Fang, C., Yu, FX.*, & Xu, Y. *(2020). USP47-mediated deubiquitination and stabilization of YAP contributes to the progression of colorectal cancer. Protein & Cell , 11(2), 138-143.

5、Fang C, Li J, Qi S, Lei Y, Zeng Y, Yu P, Hu Z, Zhou Y, Wang Y, Dai R, Li J, Huang S, Xu P, Chen K, Ding C, Yu FX*. An alternatively transcribed TAZ variant negatively regulates JAK-STAT signaling. EMBO Rep. 2019 Jun;20(6). pii: e47227.

6、Gong R, Hong AW, Plouffe SW, Zhao B, Liu G, Yu FX*,Xu Y*, Guan KL*. Opposing roles of conventional and nove PKC in the Hippo-YAP pathway regulation. Cell Res. 2015 Aug;25(8):985-8.

7、Yu FX*, Zhao B, Guan KL*. Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer. Cell. 2015 Nov 5;163(4):811-28.（Leading Edge Review）

8、Yu FX, Luo J, Mo JS, Liu G, Kim YC, Meng  Z, Zhao L, Peyman G, Ouyang H, Jiang W, Zhao J, Chen X, Zhang L, Wang CY, Bastian BC, Zhang K, Guan KL. Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP. Cancer Cell. 2014 Jun 16;25(6):822-30.

9、Yu FX, Zhang Y, Park HW, Jewell JL, Chen Q, Deng Y, Pan D, Taylor SS, Lai ZC, Guan KL. Protein Kinase A activates the Hippo pathway to modulate cell proliferation and differentiation. Genes Dev. 2013 Jun 1;27(11):1223-32.