王璞

博士,副研究员
地址:上海市东安路131号,上海 200032
邮箱:wangpu@fudan.edu.cn
1.Zeng YR#, Song JB#, Wang D, Huang ZX, Zhang C, Sun YP, Shu G, Xiong Y, Guan KL, Ye D*, Wang P*.The immunometabolite itaconate stimulates OXGR1 to promote mucociliary clearance during the pulmonary innate immune response. J Clin Invest. 2023 Mar 15;133(6):e160463. doi: 10.1172/JCI160463.
2.Sun R, Zhang Z, Bao R, Guo X, Gu Y, Yang W, Wei J, Chen X, Tong L, Meng J, Zhong C, Zhang C, Zhang J, Sun Y, Ling C, Tong X, Yu FX, Yu H, Qu W, Zhao B, Guo W, Qian M, Saiyin H, Liu Y, Liu RH, Xie C, Liu W, Xiong Y, Guan KL, Shi Y*, Wang P*, Ye D*. Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis. J Hepatol. 2022 Aug;77(2):453-466
3.Wang P., Yan F., Li Z., Yu Y., Parnell S., Xiong Y. (2019) Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development. J Clin Invest 130:4393-4407
4.Wang P., Wu J., Ma S., Zhang L., Yao J., Hoadley KA., Wilkerson MD., Perou CM., Guan KL., Ye D., Xiong Y. (2015) Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents. Cell Reports 22;13(11):2353-61
5.Wang, P., Dong, QZ., Zhang, C., Kuan, PF., Liu, YF., Jeck, WR., Jiang, WQ., Savich, GL., Tan, TX., Andersen, JB., J. Auman, JY., Hoskins, JM., Misher, AD., Moser, CD., Yourstone, SM., Kim, JW., Cibulskis, K., Getz, G., Hunt, HV., Thorgeirsson, SS., Roberts, LR., Ye, D., Guan, K-L., Xiong, Y. , Qin, L-X. , Chiang, DY. (2013) Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas . Oncogene 32(25):3091-100