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蒋恒义

发表时间:2022-02-11  |  阅读次数:12046次  |  字体大小 [ ]
  • 蒋恒义

    博士,副研究员
    地址:上海市东安路131号科研2号医学科研楼A3-025,200032
    网站: http://www.easyseq.com,https://github.com/threadtag
    邮箱:jhy@fudan.edu.cn
    电话:021-54237517

工作经历
副研究员,复旦大学,生物医学研究院/附属浦东医院(2022-至今)
助理研究员,复旦大学,生物医学研究院/附属浦东医院(2017-2022)
博士后,复旦大学,生物医学研究院(2012-2017)
教育经历
博士,复旦大学,药学院(2009-2013)
硕士,第二军医大学,基础医学院(2005-2008)
学士,东南大学,公共卫生学院(2000-2005)
研究方向
1)甲基转移酶核酶的作用机制与结构 2)新型核酶的发现 3)核酶在生物体内的功能 4)新型RNA修饰的鉴定与生物学功能
代表论文

1.Hengyi Jiang; Getong Liu; Yanqing Gao; Jianhua Gan; Dongrong Chen; Alastair I. H; Cofactor binding triggers rapid conformational remodelling of the active site of a methyltransferase ribozyme, Journal of Biological Chemistry, 2024, 300(11): 1-10

2.Getong Liu; Hengyi Jiang; Dongrong Chen; Alastair I H Murchie; Identification of Hammerhead-variant ribozyme sequences in SARS-CoV-2, Nucleic Acids Research, 2024, 2024: 1- 16

3.Hengyi Jiang; Yanqing Gao; Lei Zhang; Jianghua Gan; Dongrong Chen; Alastair I H Murchie; The identification and characterization of a selected SAM-dependent methyltransferase ribozyme that is present in natural sequences. Nature Catalysis. 2021, 4(10): 872–881.

4.Getong Liu; Hengyi Jiang; Wenxia Sun; Jun Zhang; Dongrong Chen; Alastair I H Murchie; The function of twister ribozyme variants in non-LTR retrotransposition in Schistosoma mansoni. Nucleic Acids Research. 2021, 49(18): 10573–10588.

5.Sitao Yin; HengyiJiang; Dongrong Chen; Alastair I HMurchie; Substrate recognition and modification by the nosiheptide resistance methyltransferase., PLoS One, 2015, 10(4): e0122972-e0122972.

6.Xu Jia; Jing Zhang; Wenxia Sun; Weizhi He; Hengyi Jiang; Dongrong Chen; Alastair I. H. Murchie; Riboswitch Control of Aminoglycoside Antibiotic Resistance, CELL, 2013, 152(1-2): 68-81

7.Hengyi Jiang; Wenxia Sun; Zhe Wang; Jing Zhang; Dongrong Chen; Alastair I H Murchie; Identification and characterization of the mitochondrial RNA polymerase and transcription factor in the fission yeast Schizosaccharomyces pombe, Nucleic Acids Res, 2011, 39(12): 5119-5130.

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