2020
He, S., Wu, Z., Tian, Y., Yu, Z., Yu, J., Wang, X., Li, J., Liu, B., and Xu, Y.* (2020) Structure of nucleosome-bound human BAF complex. Science 367, 875-881
Zheng, H., Qi, Y., Hu, S., Cao, X., Xu, C., Yin, Z., Chen, X., Li, Y., Liu, W., Li, J., Wang, J., Wei, G., Liang, K., Chen, F. X., and Xu, Y.* (2020) Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase. Science 370, eabb5872
Li, J.-T., Yin, M., Wang, D., Wang, J., Lei, M.-Z., Zhang, Y., Liu, Y., Zhang, L., Zou, S.-W., Hu, L.-P., Zhang, Z.-G., Wang, Y.-P., Wen, W.-Y., Lu, H.-J., Chen, Z.-J., Su, D., and Lei, Q.-Y.* (2020) BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma. Nature Cell Biology 22, 167-174
Huang, Y., Wang, H., Hao, Y., Lin, H., Dong, M., Ye, J., Song, L., Wang, Y., Li, Q., Shan, B., Jiang, Y., Li, H., Shao, Z., Kroemer, G., Zhang, H., Bai, L., Jin, T., Wang, C., Ma, Y., Cai, Y., Ding, C., Liu, S.*, Pan, Y.*, Jiang, W.*, and Zhou, R.* (2020) Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity. Nature Cell Biology
Chen, Y., Lyu, R., Rong, B., Zheng, Y., Lin, Z., Dai, R., Zhang, X., Xie, N., Wang, S., Tang, F.*, Lan, F.*, and Tong, M.-H.* (2020) Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks. Cell Research
Qu, R., Dong, L., Zhang, J., Yu, X., Wang, L.*, and Zhu, S.* (2020). Cryo-EM structure of human heptameric Pannexin 1 channel. Cell Research, 1-3.
Chen, H., Bian, F., Sun, L., Zhang, D., Shang, L. *, and Zhao, Y. * (2020) Hierarchically Molecular Imprinted Porous Particles for Biomimetic Kidney Cleaning. Advanced Materials
Zhang, W., Xu, L., Park, H.-B., Hwang, J., Kwak, M., Lee, P. C., Liang, G., Zhang, X., Xu, J., and Jin, J.-O.* (2020) Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy. Nature Communications 11, 1-14
Yang, Y., Liu, X., Shen, C., Lin, Y., Yang, P., and Qiao, L. * (2020) In silico spectral libraries by deep learning facilitate data-independent acquisition proteomics. Nature Communications 11, 1-11
Liu, Z., Yang, Y., Gu, A., Xu, J., Mao, Y., Lu, H., Hu, W., Lei, Q.-Y., Li, Z., Zhang, M., Cai, Yu.*, and Wen, W.* (2020) Par complex cluster formation mediated by phase separation. Nature Communications 11, 1-18
Tang, D.-J., Du, X., Shi, Q., Zhang, J.-L., He, Y.-P., Chen, Y.-M., Ming, Z., Wang, D., Zhong, W.-Y., Liang, Y.-W., Liu, J.-Y., Huang, J.-M., Zhong, Y.-S., An, S.-Q., Gu, H.*, and Tang, J.-L.* (2020) A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA. Nature Communications 11, 2794
Qin, Y., Chen, W., Jiang, G., Zhou, L., Yang, X., Li, H., He, X., Wang, H.-l., Zhou, Y.-b., Huang, S., and Liu, S. * (2020) Interfering MSN-NONO complex–activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer. Science Advances 6, eaaw9960
Jiao, F., Li, Z., He, C., Xu, W., Yang, G., Liu, T., Shen, H., Cai, J., Anastas, J. N., Mao, Y., Yu, Y., Lan, F., Shi, G. Y., Jones, C., Xu, Y., Baker, S.*, Shi, Y.*, and Guo, R.* (2020) RACK7 recognizes H3. 3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma. Science Advances 6, eaba2113
Zhang, Y.*, Kao, D. S., Gu, B., Bomjan, R., Srivastava, M., Lu, H. J., Zhou, D. G., and Tao, W. A.* (2020) Tracking Pathogen Infections by Time-Resolved Chemical Proteomics. Angew. Chem.-Int. Edit. 59, 2235-2240
Li Z, Lu X, Liu Y, Zhao J, Ma S, Yin H, Huang S, Zhao Y*, He X*. Gain of LINC00624 Enhances Liver Cancer Progression by Disrupting the HDAC6-TRIM28-ZNF354C Corepressor Complex. Hepatology. 2020 Sep 1. doi: 10.1002/hep.31530.
Ding, J., Zhao, J., Huan, L., Liu, Y., Qiao, Y., Wang, Z., Chen, Z., Huang, S., Zhao, Y.*, and He, X.* (2020) Inflammation-induced LINC00665 increases the malignancy through activating PKR/NF-kappa B pathway in hepatocellular carcinoma. Hepatology
Xia, Y.-K., Zeng, Y.-R., Zhang, M.-L., Liu, P., Liu, F., Zhang, H., He, C.-X., Sun, Y.-P., Zhang, J.-Y., Zhang, C., Song, L., Ding, C., Tang, Y.-J., Yang, Z., Yang, C., Wang, P., Guan, K.-L., Xiong, Y., and Ye, D.* (2020) Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network. Protein & Cell
Xia, L., Wang, X., Liu, L., Fu, J., Xiao, W., Liang, Q., Han, X., Huang, S., Sun, L., Gao, Y., Zhang, C., Yang, L., Wang, L., Qian, L.*, and Zhou, Y.* (2020) Lnc-BAZ2B promotes M2 macrophage activation and inflammation in asthmatic children through stabilizing BAZ2B pre-mRNA. Journal of Allergy and Clinical Immunology
Wu, Y. J., Zhao, Y. M., Huan, L., Zhao, J. J., Zhou, Y. Q., Xu, L. G., Hu, Z. X., Liu, Y. Z., Chen, Z. A., Wang, L., Huang, S. L.*, He, X. H.*, and Liang, L. H.* (2020) An LTR Retrotransposon-Derived Long Noncoding RNA lncMER52A Promotes Hepatocellular Carcinoma Progression by Binding p120-Catenin. Cancer Res. 80, 976-987
Cheng, Z.-L., Zhang, M.-L., Lin, H.-P., Gao, C., Song, J.-B., Zheng, Z., Li, L., Zhang, Y., Shen, X., Zhang, H., Huang, Z., Zhan, W., Zhang, C., Hu, X., Sun, Y.-P., Jiang, L., Sun, L., Xu, Y., Yang, C., Ge, Y., Zhao, Y., Liu, X., Yang, H., Liu, P., Guo, X., Guan, K.-L., Xiong, Y., Zhang, M., and Ye, D.* (2020) The Zscan4-Tet2 Transcription Nexus Regulates Metabolic Rewiring and Enhances Proteostasis to Promote Reprogramming. Cell Reports 32, 107877-107877
Rong, B., Zhang, Q., Wan, J., Xing, S., Dai, R., Li, Y., Cai, J., Xie, J., Song, Y., Chen, J., Zhang, L., Yan, G., Zhang, W., Gao, H., Han, J.-D. J., Qu, Q., Ma, H., Tian, Y., and Lan, F. (2020) Ribosome 18S m6A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth. Cell Reports 33, 108544
Wan, J., Xing, S., Ding, L., Wang, Y., Gu, C., Wu, Y., Rong, B., Li, C., Wang, S., Chen, K., He, C., Zhu, D., Yuan, S., Qiu, C., Zhao, C., Nie, L., Gao, Z., Jiao, J., Zhang, X., Wang, X., Ying, T., Wang, H., Xie, Y.*, Lu, Y.*, Xu, J.*, and Lan, F.* (2020) Human-IgG-Neutralizing Monoclonal Antibodies Block the SARS-CoV-2 Infection. Cell Reports 32, 107918-107918
Mei, X.*, Qi, D., Zhang, T., Zhao, Y., Jin, L., Hou, J., Wang, J., Lin, Y., Xue, Y., Zhu, P., Liu, Z., Huang, L., Nie, J., Si, W., Ma, J., Ye, J., Finnell, R., H , Saiyin, H., Wang, H.*, Zhao, J.*, Zhao, S.*, and Xu, W.* (2020) Inhibiting MARSs reduces hyperhomocysteinemia‐associated neural tube and congenital heart defects. EMBO Molecular Medicine
Xu J*, Brosseau JP, Shi H. Targeted degradation of immune checkpoint proteins: emerging strategies for cancer immunotherapy. Oncogene. 2020 Oct 6. doi: 10.1038/s41388-020-01491-w.
He, Y., Fu, W., Cao, K., He, Q., Ding, X., Chen, J., Zhu, L., Chen, T., Ding, L., Yang, Y., Zhu, C., Yuan, S., Li, Z., Chen, C.*, Zhang, X.*, and Xu, J.* (2020) IFN-κ suppresses the replication of influenza A viruses through the IFNAR-MAPK-Fos-CHD6 axis. Science Signaling 13(Cover story)
Huang, S., Xue, P., Han, X., Zhang, C., Yang, L., Liu, L., Wang, X., Li, H., Fu, J.*, and Zhou, Y.* (2020) Exosomal miR-130b-3p targets SIK1 to inhibit medulloblastoma tumorigenesis. Cell Death & Disease 11, 408
Zhang, Y., and Lei, Q.-Y. (2020) Rewiring local immune milieu by boosting dendritic cell for pancreatic cancer treatment. Signal Transduction and Targeted Therapy 5
Hao, Q.*, Wang, J. Q., Chen, Y. J., Wang, S. S., Cao, M. M., Lu, H., and Zhou, X.* (2020) Dual regulation of p53 by the ribosome maturation factor SBDS. Cell Death & Disease 11, 15
Zhao, C., Zhu, Y., Kong, B., Huang, Y., Yan, D., Tan, H., and Shang, L. * (2020) Dual-Core Prebiotic Microcapsule Encapsulating Probiotics for Metabolic Syndrome. Acs Applied Materials & Interfaces 12, 42586-42594
Li, Q., Zhang, S., Li, W., Ge, Z., Fan, C., and Gu, H. (2020) Programming CircLigase Catalysis for DNA Rings and Topologies. Analytical Chemistry
Hu, Y., Zhang, L., Chen, J., Yao, J., Jin, H., and Yang, P. (2020) Outer Membrane Protease OmpT-Based Strategy for Simplified Analysis of Histone Post-Translational Modifications by Mass Spectrometry. Analytical Chemistry 92, 732-739
Fang, P., Xie, J., Sang, S., Zhang, L., Liu, M., Yang, L., Xu, Y., Yan, G., Yao, J., Gao, X., Qian, W., Wang, Z., Zhang, Y., Yang, P., and Shen, H. (2020) Multilayered N-Glycoproteome Profiling Reveals Highly Heterogeneous and Dysregulated Protein N-Glycosylation Related to Alzheimer's Disease. Analytical Chemistry 92, 867-874
Du, X. X., Lu, J. T., Yang, L. J., Bao, H. M., Zhang, L., Yan, G. Q., Fang, C. Y., and Lu, H. J. (2020) Rapid and Easy Enrichment Strategy for Naturally Acetylated N Termini Based on LysN Digestion and Amine-Reactive Resin Capture. Analytical Chemistry 92, 8315-8322
Zhang, X., Sun, W., Chen, D.*, and Murchie, A. I.* (2020) Interactions between SAM and the 5′ UTR mRNA of the sam1 gene regulate translation in S. pombe. RNA 26, 150-161
Guan, S., Yu, H., Yan, G., Gao, M., Sun, W.*, and Zhang, X.* (2020) Characterization of Urinary Exosomes Purified with Size Exclusion Chromatography and Ultracentrifugation. Journal of Proteome Research19, 2217–2225(张祥民)
Chen J, Chen Z, Liu M, Qiu T, Feng D, Zhao C, Zhang S, Zhang X, Xu J. Placental Alkaline Phosphatase Promotes Zika Virus Replication by Stabilizing Viral Proteins through BIP. mBio. 2020 Sep 15;11(5):e01716-20. doi: 10.1128/mBio.01716-20.
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Fu W, Liu Y, Liu L, Hu H, Cheng X, Liu P, Song Z, Zha L, Bai S, Xu T, Yuan S, Lu F, Shang Z, Zhao Y, Wang J, Zhao J, Ding L, Chen J, Zhang L, Zhu T, Zhang X, Lu H, Xu J. An open-label, randomized trial of the combination of IFN-κ plus TFF2 with standard care in the treatment of patients with moderate COVID-19. EClinicalMedicine. 2020 Sep 20:100547. doi: 10.1016/j.eclinm.2020.100547.
Gu Y, Wang X, Wang Y, Wang Y, Li J, Yu FX. Nelfinavir inhibits human DDI2 and potentiates cytotoxicity of proteasome inhibitors. Cell Signal. 2020 Nov;75:109775. doi: 10.1016/j.cellsig.2020.109775.
Chen, J., Ge, X., Zhang, W., Ding, P., Du, Y., Wang, Q., Li, L., Fang, L., Sun, Y., Zhang, P., Zhou, Y., Zhang, L., Lv, X., Li, L., Zhang, X., Zhang, Q., Xue, K., Gu, H., Lei, Q., Wong, J., and Hu, W. (2020) PI3K/AKT inhibition reverses R-CHOP resistance by destabilizing SOX2 in diffuse large B cell lymphoma. Theranostics 10, 3151-3163
Zhang, C., Han, X., Yang, L., Fu, J., Sun, C., Huang, S., Xiao, W., Gao, Y., Liang, Q., Wang, X., Luo, F., Lu, W., and Zhou, Y. (2020) Circular RNA circPPM1F modulates M1 macrophage activation and pancreatic islet inflammation in type 1 diabetes mellitus. Theranostics 10, 10908-10924
Zhou, L., Wang, D., Sheng, D., Xu, J., Chen, W., Qin, Y., Du, R., Yang, X., He, X., Xie, N., Liu, S., and Zhang, L. (2020) NOTCH4 maintains quiescent mesenchymal-like breast cancer stem cells via transcriptionally activating SLUG and GAS1 in triple-negative breast cancer. Theranostics 10, 2405-2421
Yang, L.-F., Yang, F., Zhang, F.-L., Xie, Y.-F., Hu, Z.-X., Huang, S.-L., Shao, Z.-M., and Li, D-Q. (2020) Discrete functional and mechanistic roles of chromodomain Y-like 2 (CDYL2) transcript variants in breast cancer growth and metastasis. Theranostics 10, 5242-5258
Ma, D., Fetahu, I. S., Wang, M., Fang, R., Li, J., Liu, H., Gramyk, T., Iwanicki, I., Gu, S., Xu, W., Tan, L., Wu, F., and Shi, Y. G. (2020) The fusiform gyrus exhibits an epigenetic signature for Alzheimer's disease. Clinical epigenetics 12, 129
Guo, J., Zhang, Q., Su, Y., Lu, X., Wang, Y., Yin, M., Hu, W., Wen, W., and Lei, Q.-Y. (2020) Arginine methylation of ribose-5-phosphate isomerase A senses glucose to promote human colorectal cancer cell survival. Science China Life Sciences, 1-12
Zhang, F., and Liu, S. (2020) Mechanistic insights of adipocyte metabolism in regulating breast cancer progression. Pharmacological Research, 104741
Wen, Z., Wang, Y., Qi, S., Ma, M., Li, J., and Yu, F.-X. (2020) Regulation of TP73 transcription by Hippo-YAP signaling. Biochemical and biophysical research communications 531, 96-104
Xie, J. J., Zhang, L., Chen, Z. W., Hu, A. Q., Liu, S. S., Lu, D. B., Xia, Y., Qian, J. Y., Yang, P. Y., and Shen, H. L. (2020) Protein-protein correlations based variable dimension expansion algorithm for high efficient serum biomarker discovery. Analytica Chimica Acta 1119, 25-34
Shang, L., and Zhao, Y. (2020) Tiny water droplet with huge power. Science Bulletin 65, 693-695
Zhu, X., Ding, S., Li, H., Zhang, Z., Xu, L., Wu, J., Wang, X., Zou, Y., Yang, X., and Ge, J. (2020) Disruption of histamine/H1R signaling pathway represses cardiac differentiation and maturation of human induced pluripotent stem cells. Stem Cell Research & Therapy 11
Huang, Y., Zhang, Q., Liu, Y., Jiang, B., Xie, J., Gong, T., Jia, B., Liu, X., Yao, J., Cao, W., Shen, H., and Yang, P. (2020) Aperture-controllable nano-electrospray emitter and its application in cardiac proteome analysis. Talanta 207
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