• Li, C., Zhan, W., Yang, Z., Tu, C., Hu, G., Zhang, X., Song, W., Du, S., Zhu, Y., Huang, K., Kong, Y., Zhang, M., Mao, Q., Gu, X., Zhang, Y., Xie, Y., Deng, Q., Song, Y., Chen, Z., Lu, L., Jiang, S., Wu, Y.*, Sun, L.*, and Ying, T.* (2022) Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody. Cell 

• Chen, B., Du, Y.-R., Zhu, H., Sun, M.-L., Wang, C., Cheng, Y., Pang, H., Ding, G., Gao, J., Tan, Y., Tong, X., Lv, P., Zhou, F., Zhan, Q., Xu, Z.-M., Wang, L., Luo, D., Ye, Y., Jin, L., Zhang, S., Zhu, Y., Lin, X., Wu, Y., Jin, L., Zhou, Y., Yan, C., Sheng, J., Flatt, P. R., Xu, G.-L.*, and Huang, H*. (2022) Maternal inheritance of glucose intolerance via oocyte TET3 insufficiency. Nature

• Chen, X., Wang, X., Liu, W., Ren, Y., Qu, X., Li, J., Yin, X., and Xu, Y.* (2022) Structures of +1 nucleosome–bound PIC-Mediator complex. Science 378, 62-68

• Chen, L.-L., Morcelle, C., Cheng, Z.-L., Chen, X., Xu, Y., Gao, Y., Song, J., Li, Z., Smith, M. D., Shi, M., Zhu, Y., Zhou, N., Cheng, M., He, C., Liu, K. Y., Lu, G., Zhang, L., Zhang, C., Zhang, J., Sun, Y., Qi, T., Lyu, Y., Ren, Z.-Z., Tan, X.-M., Yin, J., Lan, F., Liu, Y., Yang, H., Qian, M., Duan, C., Chang, X., Zhou, Y., Shen, L., Baldwin, A. S., Guan, K.-L., Xiong, Y., and Ye, D.* (2022) Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses. Nature Cell Biology 

• Wang, Z., Lu, Z., Lin, S., Xia, J., Zhong, Z., Xie, Z., Xing, Y., Qie, J., Jiao, M., Li, Y., Wen, H., Zhao, P., Zhang, D., Zhou, P., Qian, J., Luo, F., Wang, L., Yu, H., Liu, J., Gu, J., Liu, R.*, and Chu, Y.* (2022) Leucine-tRNA-synthase-2-expressing B cells contribute to colorectal cancer immunoevasion. Immunity 

• Hu, L*., Liu, S., Peng, Y., Ge, R., Su, R., Senevirathne, C., Harada, B. T., Dai, Q., Wei, J., Zhang, L., Hao, Z., Luo, L., Wang, H., Wang, Y., Luo, M., Chen, M*., Chen, J.*, and He, C.* (2022) m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome. Nature Biotechnology 

• Qi, S., Zhu, Y., Liu, X., Li, P., Wang, Y., Zeng, Y., Yu, A., Wang, Y., Sha, Z., Zhong, Z., Zhu, R., Yuan, H., Ye, D., Huang, S., Ling, C., Xu, Y., Zhou, D., Zhang, L., and Yu, F.-X.* (2022) WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy. Molecular Cell ）

• Ma, Q.-X., Zhu, W.-Y., Lu, X.-C., Jiang, D., Xu, F., Li, J.-T., Zhang, L., Wu, Y.-L., Chen, Z.-J., Yin, M.*, Huang, H.-Y.*, and Lei, Q.-Y.* (2022) BCAA–BCKA axis regulates WAT browning through acetylation of PRDM16. Nature Metabolism 4, 106-122

• Sun, X., Yi, C., Zhu, Y., Ding, L., Xia, S., Chen, X., Liu, M., Gu, C., Lu, X., Fu, Y., Chen, S., Zhang, T., Zhang, Y., Yang, Z., Ma, L., Gu, W., Hu, G., Du, S., Yan, R., Fu, W., Yuan, S., Qiu, C., Zhao, C., Zhang, X., He, Y., Qu, A., Zhou, X., Li, X., Wong, G., Deng, Q., Zhou, Q., Lu, H., Ling, Z.*, Ding, J.*, Lu, L.*, Xu, J.*, Xie, Y.*, and Sun, B.* (2022) Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2. Nature Microbiology 7, 1063-1074

• Wang, Y., Zhan, W., Liu, J., Wang, Y., Zhang, X., Zhang, M., Han, L., Ma, Y., Lu, L., Wen, Y., Chen, Z., Zhao, J.*, Wu, F.*, Sun, L.*, and Huang, J.* (2022) A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding. Cell Research

• Xiong, Y., Zheng, Y., Yan, Y., Yao, J., Liu, H., Shen, F., Kong, S., Yang, S., Yan, G., Zhao, H., Zhou, X., Hu, J., Zhou, B., Jin, T., Shen, H., Leng, B.*, Yang, P., and Liu, X.* Circulating proteomic panels for risk stratification of intracranial aneurysm and its rupture. EMBO Molecular Medicine , e14713

• Jiang, L., Yin, J., Qian, M., Rong, S., Zhang, S., Chen, K., Zhao, C., Tan, Y., Guo, J., Chen, H., Gao, S., Liu, T., Liu, Y., Shen, B., Yang, J., Zhang, Y., Meng, F.-L., Hu, J.*, Ma, H.*, and Chen, Y.-H.* (2022) UdgX-Mediated Uracil Sequencing at Single-Nucleotide Resolution. Journal of the American Chemical Society 

• Chen, X., Zhou, W., Song, R.-H., Liu, S., Wang, S., Chen, Y., Gao, C., He, C., Xiao, J., Zhang, L., Wang, T., Liu, P., Duan, K., Cheng, Z., Zhang, C., Zhang, J., Sun, Y., Jackson, F., Lan, F., Liu, Y., Xu, Y., Wong, J. J.-L., Wang, P., Yang, H., Xiong, Y., Chen, T*, Li, Y.*, and Ye, D.* (2022) Tumor suppressor CEBPA interacts with and inhibits DNMT3A activity. Science Advances 8, eabl5220

• Xu, W., He, C., Kaye, E. G., Li, J., Mu, M., Nelson, G. M., Dong, L., Wang, J., Wu, F., Shi, Y. G., Adelman, K., Lan, F.*, Shi, Y.*, and Shen, H.* (2022) Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis. Molecular Cell

• Sun, R., Zhang, Z., Bao, R., Guo, X., Gu, Y., Yang, W., Wei, J., Chen, X., Tong, L., Meng, J., Zhong, C., Zhang, C., Zhang, J., Sun, Y., Ling, C., Tong, X., Yu, F.-X., Yu, H., Qu, W., Zhao, B., Guo, W., Qian, M., Saiyin, H., Liu, Y., Liu, R.-H., Xie, C., Liu, W., Xiong, Y., Guan, K.-L., Shi, Y.*, Wang, P.*, and Ye, D.* (2022) Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis. Journal of Hepatology 

• Hu, S.-H., He, X.-D., Nie, J., Hou, J.-L., Wu, J., Liu, X.-Y., Wei, Y., Tang, H.-R., Sun, W.-X., Zhou, S.-X., Yuan, Y.-Y., An, Y.-P., Yan, G.-Q., Lin, Y., Lin, P.-C., Zhao, J. J., Ye, M.-L*., Zhao, J.-Y.*, Xu, W.*, and Zhao, S.-M.* (2022) Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake. Cell Reports 38, 110509

• Gong, T.-Q., Jiang, Y.-Z., Shao, C., Peng, W.-T., Liu, M.-W., Li, D.-Q., Zhang, B.-Y., Du, P., Huang, Y., Li, F.-F., Li, M.-Y., Han, Z.-L., Jin, X., Ma, D., Xiao, Y., Yang, P.-Y., Qin, J.*, Shao, Z.-M.*, and Zhu, W.* (2022) Proteome-centric cross-omics characterization and integrated network analyses of triple-negative breast cancer. Cell Reports 38（IBS为第一单位）

• Li, X.*, Zhou, L., Gao, B.-Q., Li, G., Wang, X., Wang, Y., Wei, J., Han, W., Wang, Z., Li, J., Gao, R., Zhu, J., Xu, W., Wu, J., Yang, B., Sun, X.*, Yang, L.*, and Chen, J.* (2022) Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure. Nature Communications 13, 1669

• Wang, Z., Song, A., Xu, H., Hu, S., Tao, B., Peng, L., Wang, J., Li, J., Yu, J., Wang, L., Li, Z., Chen, X., Wang, M., Chi, Y., Wu, J., Xu, Y., Zheng, H., and Chen, F. X.* (2022) Coordinated regulation of RNA polymerase II pausing and elongation progression by PAF1. Science Advances 8, eabm5504

• Wang, X., Qi, Y., Wang, Z., Wang, L., Song, A., Tao, B., Li, J., Zhao, D., Zhang, H., Jin, Q., Jiang, Y.-Z., Chen, F. X*., Xu, Y.*, and Chen, X.* (2022) RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex. Cell Reports 39, 110732

• Xu, Y., Jia, G., Li, T., Zhou, Z., Luo, Y., Chao, Y., Bao, J., Su, Z.*, Qu, Q.*, and Li, D.* (2022) Molecular insights into biogenesis of glycosylphosphatidylinositol anchor proteins. Nature Communications 13, 2617

• Ding, P., Xu, Y., Li, L., Lv, X., Li, L., Chen, J., Zhou, D., Wang, X., Wang, Q., Zhang, W., Liao, T., Ji, Q.-H., Lei, Q.-Y., and Hu, W.* (2022) Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis. Cell Reports 39, 110851

• Liu, Z., Ye, Y., Liu, Y., Liu, Y., Chen, H., Shen, M., Wang, Z., Huang, S., Han, L., Chen, Z., and He, X. * (2022) RNA Helicase DHX37 Facilitates Liver Cancer Progression by Cooperating with PLRG1 to Drive Superenhancer-Mediated Transcription of Cyclin D1. Cancer Res. 82, 1937-1952

• Li, H., Song, J., He, Y., Liu, Y., Liu, Z., Sun, W., Hu, W., Lei, Q.-Y., Hu, X., Chen, Z.*, and He, X. *  CRISPR/Cas9 Screens Reveal that Hexokinase 2 Enhances Cancer Stemness and Tumorigenicity by Activating the ACSL4-Fatty Acid β-Oxidation Pathway. Advanced Science n/a, 2105126

Yin, Y., Liu, B., Cao, Y., Yao, S., Liu, Y., Jin, G., Qin, Y., Chen, Y., Cui, K., Zhou, L., Bian, Z., Fei, B., Huang, S.*, and Huang, Z.* (2022) Colorectal Cancer-Derived Small Extracellular Vesicles Promote Tumor Immune Evasion by Upregulating PD-L1 Expression in Tumor-Associated Macrophages. Advanced Science 9, 2102620

• Lai, H., Li, Y., Zhang, H., Hu, J., Liao, J., Su, Y., Li, Q., Chen, B., Li, C., Wang, Z., Li, Y., Wang, J., Meng, Z.*, Huang, Z.*, and Huang, S.* (2021) exoRBase 2.0: an atlas of mRNA, lncRNA and circRNA in extracellular vesicles from human biofluids. Nucleic Acids Research 50, D118-D128

• Wu, S., Huang, Y., Selby, C. P., Gao, M., Sancar, A. *, and Hu, J. *  (2022) A new technique for genome-wide mapping of nucleotide excision repair without immunopurification of damaged DNA. Journal of Biological Chemistry 298, 101863

• Liu, P., Sun, S.-J., Ai, Y.-J., Feng, X., Zheng, Y.-M., Gao, Y., Zhang, J.-Y., Zhang, L., Sun, Y.-P., Xiong, Y., Lin, M.*, and Yuan, H.-X. *  (2022) Elevated nuclear localization of glycolytic enzyme TPI1 promotes lung adenocarcinoma and enhances chemoresistance. Cell Death & Disease 13, 205

• Wu, L., Fei, W., Liu, Z., Zhang, L., Fang, C.*, and Lu, H. * (2022) Specific and Reversible Enrichment of Early-Stage Glycated Proteome Based on Thiazolidine Chemistry and Palladium-Mediated Cleavage. Analytical Chemistry 94, 5213-5220

• Liu, Y.-Y., Liu, H.-Y., Yu, T.-J., Lu, Q., Zhang, F.-L., Liu, G.-Y.*, Shao, Z.-M.*, and Li, D.-Q. *  (2022) O-GlcNAcylation of MORC2 at threonine 556 by OGT couples TGF-β signaling to breast cancer progression. Cell Death & Differentiation 29, 861-873

• Zhang, Y.-L., Deng, L., Liao, L., Yang, S.-Y., Hu, S.-Y., Ning, Y.*, Zhang, F.-L.*, and Li, D.-Q. * (2022) Chromatin complexes subunit BAP18 promotes triple-negative breast cancer progression through transcriptional activation of oncogene S100A9. Cell Death & Disease 13, 408

• Yu, S.-X., Liu, Y., Wu, Y., Luo, H., Huang, R., Wang, Y.-J., Wang, X., Gao, H., Shi, H.*, Jing, G*., and Liu, Y.-J. * (2022) Cervix chip mimicking cervical microenvironment for quantifying sperm locomotion. Biosensors and Bioelectronics 204, 114040

• Wang, J., Huang, D., Ren, H.* , and Shang, L. * Biomimic Trained Immunity-MSCs Delivery Microcarriers for Acute Liver Failure Regeneration. Small n/a, 2200858

• Zhang, Z., Wang, Y., Wang, Q., and Shang, L. * Smart Film Actuators for Biomedical Applications. Small n/a, 2105116

• Zhenyu Sun, Bin Fu, Guoli Wang, Lei Zhang, Ruofan Xu, Ying Zhang*, Haojie Lu*, High-throughput site-specific N-glycoproteomics reveals glyco-signatures for liver disease diagnosis, National Science Review, 2022;, nwac059

• Zhou, Q., Sun, W.-W., Chen, J.-C., Zhang, H.-L., Liu, J., Lin, Y., Lin, P.-C., Wu, B.-X., An, Y.-P., Huang, L., Sun, W.-X., Zhou, X.-W., Li, Y.-M., Yuan, Y.-Y., Zhao, J.-Y., Xu, W.*, and Zhao, S.-M.* (2022) Phenylalanine impairs insulin signaling and inhibits glucose uptake through modification of IRβ. Nature Communications 13, 4291

• Zhang, Z., Wang, C., Wang, Q., Zhao, Y.*, and Shang, L.* (2022) Cholesteric cellulose liquid crystal ink for three-dimensional structural coloration. Proceedings of the National Academy of Sciences 119, e2204113119

• Liu, J., Chen, L., Zhai, T., Li, W., Liu, Y., and Gu, H.* (2022) Programmable Assembly of Amphiphilic DNA through Controlled Cholesterol Stacking. Journal of the American Chemical Society 

• Gu, Y., Wang, Y., Sha, Z., He, C., Zhu, Y., Li, J., Yu, A., Zhong, Z., Wang, X., Sun, Y., Lan, F., and Yu, F.-X.* (2022) Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers. Cell Reports 40

• Liang, Q., Fu, J., Wang, X., Liu, L., Xiao, W., Gao, Y., Yang, L., Yu, H., Xueru, X., Zikun, T., Huang, S., Han, X., Qian, L.*, and Zhou, Y.* circS100A11 enhances M2a macrophage activation and lung inflammation in children with asthma. Allergy 

• Yang L*, Wilusz JE* and Chen LL*. Biogenesis and Regulatory Roles of Circular RNAs. Annu Rev Cell Dev Biol, 2022, 10.1146/annurev-cellbio-120420-125117   

• Chen, X., and Xu, Y.* (2022) Structural insights into assembly of transcription preinitiation complex. Current Opinion in Structural Biology 75, 102404 

• Chen, X., Qi, Y., Wu, Z., Wang, X., Li, J., Zhao, D., Hou, H., Li, Y., Yu, Z., Liu, W., Wang, M., Ren, Y., Li, Z., Yang, H., and Xu, Y.* (2021) Structural insights into preinitiation complex assembly on core promoters. Science, eaba8490

• Chen, X., Yin, X., Li, J., Wu, Z., Qi, Y., Wang, X., Liu, W., and Xu, Y.*(2021) Structures of the human Mediator and Mediator-bound preinitiation complex. Science, eabg0635

• Xu, W., Li, J., He, C., Wen, J., Ma, H., Rong, B., Diao, J., Wang, L., Wang, J., Wu, F., Tan, L., Shi, Y. G., Shi, Y.*, and Shen, H.* (2021) METTL3 regulates heterochromatin in mouse embryonic stem cells. Nature

• Han, L., Qu, Q., Aydin, D., Panova, O., Robertson, M. J., Xu, Y., Dror, R. O., Skiniotis, G., and Feng, L. * (2021) Structure and mechanism of the SGLT family of glucose transporters. Nature

• Jiang, H., Gao, Y., Zhang, L., Chen, D.*, Gan, J.*, and Murchie, A. I. H.* (2021) The identification and characterization of a selected SAM-dependent methyltransferase ribozyme that is present in natural sequences. Nature Catalysis 4, 872-881

• Yang, Y., Wu, Z., Wang, L., Zhou, K., Xia, K., Xiong, Q., Liu, L., Zhang, Z., Chapman, E. R., Xiong, Y., Melia, T. J., Karatekin, E., Gu, H.*, and Lin, C.* (2021) Sorting sub-150-nm liposomes of distinct sizes by DNA-brick-assisted centrifugation. Nature Chemistry

• Jia Y, Chen L, Liu J, Li W, Gu H.* (2021) DNA-catalyzed efficient production of single-stranded DNA nanostructures. Chem

• Wang, Y., Tian, Q., Hao, Y., Yao, W., Lu, J., Chen, C., Chen, X., Lin, Y., Huang, Q., Xu, L., Hu, J., Lei, S., Wei, Z., Luo, Y., Li, Z., Hu, L., Tang, J., Wu, Q., Zhou, X., Wu, Y., Yin, Z. *, Xu, J. *, and Ye, L. * (2021) The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4+ T cells by preventing ferroptosis. Nature Immunology

• Hu, S., Peng, L., Xu, C., Wang, Z., Song, A., and Chen, F. X.* (2021) SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape. Molecular Cell 

• Li, L., Yu, Z., Zhao, D., Ren, Y., Hou, H., and Xu, Y.* (2021) Structure of human RNA polymerase III elongation complex. Cell Research

• Gu, Y., Cao, J., Zhang, X., Gao, H., Wang, Y., Wang, J., He, J., Jiang, X., Zhang, J., Shen, G., Yang, J., Zheng, X., Hu, G., Zhu, Y., Du, S., Zhu, Y., Zhang, R., Xu, J., Lan, F., Qu, D., Xu, G., Zhao, Y.*, Gao, D.*, Xie, Y.*, Luo, M.*, and Lu, Z.* (2021) Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2. Cell Research 

• Xu, X., Ding, G., Liu, C., Ding, Y., Chen, X., Huang, X., Zhang, C.-S., Lu, S., Zhang, Y., Huang, Y., Chen, Z., Wei, W., Liao, L., Lin, S.-H., Li, J., Liu, W., Li, J., Lin, S.-C., Ma, X.*, and Wong, J.* (2021) Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function. Cell Research 

• Shi, J., Zhang, Y., Tan, D., Zhang, X., Yan, M., Zhang, Y., Franklin, R., Shahbazi, M., Mackinlay, K., Liu, S., Kuhle, B., James, E. R., Zhang, L., Qu, Y., Zhai, Q., Zhao, W., Zhao, L., Zhou, C., Gu, W., Murn, J., Guo, J., Carrell, D. T., Wang, Y., Chen, X., Cairns, B. R., Yang, X.-l., Schimmel, P., Zernicka-Goetz, M., Cheloufi, S., Zhang, Y., Zhou, T., and Chen, Q. (2021) PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications. Nature Cell Biology

• Wang,Y.-P.,Sharda, A., Xu, S.-N., van Gastel, N., Man, C. H., Choi, U., Leong, W. Z., Li, X., and Scadden, D. T. (2021) Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis. Cell Metabolism

• Zeng, W.-F.*, Cao, W.-Q., Liu, M.-Q., He, S.-M., and Yang, P.-Y. (2021) Precise, fast and comprehensive analysis of intact glycopeptides and modified glycans with pGlyco3. Nature Methods 

• Tsutsumi, N.#, Qu, Q.#, Mavri, M., Baggesen, M. S., Maeda, S., Waghray, D., Berg, C., Kobilka, B. K., Rosenkilde, M. M., Skiniotis, G., and Garcia, K. C. (2021) Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1.Immunity

• Shi, H., Gao, Y., Dong, Z., Yang, J. e., Gao, R., Li, X., Zhang, S., Ma, L., Sun, X., Wang, Z., Zhang, F., Hu, K., Sun, A. *, and Ge, J. * (2021) GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury. Circulation Research 129, 383-396

• Zhang, J.-J., Fan, T.-T., Mao, Y.-Z., Hou, J.-L., Wang, M., Zhang, M., Lin, Y., Zhang, L., Yan, G.-Q., An, Y.-P., Yao, J., Zhang, C., Lin, P.-C., Yuan, Y.-Y., Zhao, J.-Y., Xu, W.*, and Zhao, S.-M.* (2021) Nuclear dihydroxyacetone phosphate signals nutrient sufficiency and cell cycle phase to global histone acetylation. Nature Metabolism

• Yang, H.*, Yu, Z., Chen, X., Li, J., Li, N., Cheng, J., Gao, N., Yuan, H.-X., Ye, D., Guan, K.-L., and Xu, Y.* Structural insights into TSC complex assembly and GAP activity on Rheb. Nature Communications 12, 339 (2021).

• Yang, Y., Yan, G., Kong, S., Wu, M., Yang, P., Cao, W.*, and Qiao, L.* (2021) GproDIA enables data-independent acquisition glycoproteomics with comprehensive statistical control. Nature Communications 12, 6073

• Hou, H., Li, Y., Wang, M., Liu, A., Yu, Z., Chen, K., Zhao, D., and Xu, Y.* (2021) Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine. Nature Communications 12, 6135

• Xu, J., Yang, X., Deng, Q., Yang, C., Wang, D., Jiang, G., Yao, X., He, X., Ding, J., Qiang, J., Tu, J., zhang, R., Lei, Q.-Y., Shao, Z.-m., Bian, X.*, Hu, R.*, Zhang, L.*, and Liu, S.* (2021) TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer. Nature Communications 12, 4413

• Chen, C., Hao, X., Lai, X., Liu, L., Zhu, J., Shao, H., Huang, D., Gu, H., Zhang, T., Yu, Z., Xie, L., Zhang, X., Yang, Y., Xu, J.*, Zhao, Y.*, Lu, Z.*, and Zheng, J.* (2021) Oxidative phosphorylation enhances the leukemogenic capacity and resistance to chemotherapy of B cell acute lymphoblastic leukemia. Science Advances 7, eabd6280

• Zhang, H., Qin, Z., Yue, X., Liu, Y., Sun, X., Feng, J., Xu, Z., Zhao, J., Li, K., Qiu, J., Yang, W.*, He, F.*, and Ding, C.* (2021) Proteome-wide profiling of transcriptional machinery on accessible chromatin with biotinylated transposons. Science Advances 7, eabh1022

• Zhao, Y., Du, X., Duan, Y., Pan, X., Sun, Y., You, T., Han, L., Jin, Z., Shang, W., Yu, J., Guo, H., Liu, Q., Wu, Y., Peng, C., Wang, J., Zhu, C., Yang, X., Yang, K., Lei, Y., Guddat, L. W., Xu, W., Xiao, G., Sun, L.*, Zhang, L.*, Rao, Z.*, and Yang, H.* (2021) High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors. Protein & Cell

• Liu, Z., Xu, W., Chen, Z., Fu, W., Zhan, W., Gao, Y., Zhou, J., Zhou, Y., Wu, J., Wang, Q., Zhang, X., Hao, A., Wu, W., Zhang, Q., Li, Y., Fan, K., Chen, R., Jiang, Q., Mayer, C. T., Schoofs, T., Xie, Y., Jiang, S., Wen, Y., Yuan, Z.*, Wang, K.*, Lu, L.*, Sun, L.*, and Wang, Q.* (2021) An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope. Protein & Cell 

• Li, J.-T., Li, K.-Y., Su, Y., Shen, Y., Lei, M.-Z., Zhang, F., Yin, M., Chen, Z.-J., Wen, W.-Y., Hu, W.-G., Su, D. *, Qu, J. *, and Lei, Q.-Y. * (2021) Diet high in branched-chain amino acid promotes PDAC development by USP1-mediated BCAT2 stabilization. National Science Review

• Yang, L., Yan, X., Chen, J., Zhan, Q., Hua, Y., Xu, S., Li, Z., Wang, Z., Dong, Y., Zuo, D., Xue, M., Tang, Y., Herschman, H. R., Lu, S.*, Shi, Q.*, and Wei, W.* (2021) Hexokinase 2 discerns a novel circulating tumor cell population associated with poor prognosis in lung cancer patients. PNAS 118, e2012228118

• Chen, Y., Hao, Q., Wang, S., Cao, M., Huang, Y., Weng, X., Wang, J., Zhang, Z., He, X., Lu, H., and Zhou, X.* (2021) Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP. PNAS 118, e2026813118

• Chen, J., Fan, J., Chen, Z., Zhang, M., Peng, H., Liu, J., Ding, L., Liu, M., Zhao, C., Zhao, P., Zhang, S*., Zhang, X*., and Xu, J*. (2021) Nonmuscle myosin heavy chain IIA facilitates SARS-CoV-2 infection in human pulmonary cells. PNAS 118, e2111011118

• Liu, C., Qiang, J., Deng, Q., Xia, J., Deng, L., Zhou, L., Wang, D., He, X., Liu, Y., Zhao, B., Lv, J., Yu, Z., Lei, Q.-Y., Shao, Z.-M., Zhang, X.-Y., Zhang, L., and Liu, S. * (2021) ALDH1A1 Activity in Tumor-Initiating Cells Remodels Myeloid-Derived Suppressor Cells to Promote Breast Cancer Progression. Cancer Research. 81, 5919-5934

• Zhang, C., Li, Q., Xu, T., Li, W., He, Y., and Gu, H.*(2021) New DNA-hydrolyzing DNAs isolated from an ssDNA library carrying a terminal hybridization stem. Nucleic Acids Research

• Liang, Y., Lu, Q., Li, W., Zhang, D., Zhang, F., Zou, Q., Chen, L., Tong, Y., Liu, M., Wang, S., Li, W., Ren, X., Xu, P., Yang, Z., Dong, S., Zhang, B., Huang, Y., Li, D.*, Wang, H.*, and Yu, W.* (2021) Reactivation of tumour suppressor in breast cancer by enhancer switching through NamiRNA network. Nucleic Acids Research

• Liu, G., Jiang, H., Sun, W., Zhang, J., Chen, D.*, and Murchie, A. I. H.* (2021) The function of twister ribozyme variants in non-LTR retrotransposition in Schistosoma mansoni. Nucleic Acids Research 49, 10573-10588

• Niu, C., Wang, S., Guo, J., Wei, X., Jia, M., Chen, Z., Gong, W., Qin, Y., Wang, X., Zhi, X., Lu, M., Chen, S., Gu, M., Zhang, J., Han, J.-D. J., Lan, F.*, and Meng, D*. (2021) BACH1 recruits NANOG and histone H3 lysine 4 methyltransferase MLL/SET1 complexes to regulate enhancer–promoter activity and maintains pluripotency. Nucleic Acids Research 

• Li, Q., Lai, H., Li, Y., Chen, B., Chen, S., Li, Y., Huang, Z., Meng, Z., Wang, P., Hu, Z.*, and Huang, S.* (2021) RJunBase: a database of RNA splice junctions in human normal and cancerous tissues. Nucleic Acids Research 49, D201-D211

• An, J., Yin, M., Yin, J., Wu, S., Selby, C. P., Yang, Y., Sancar, A., Xu, G.-L., Qian, M.*, and Hu, J.* (2021) Genome-wide analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine at single-nucleotide resolution unveils reduced occurrence of oxidative damage at G-quadruplex sites. Nucleic Acids Research

• Yang, L., Fu, J., Han, X., Zhang, C., Xia, L., Zhu, R., Huang, S., Xiao, W., Yu, H., Gao, Y., Liang, Q., Li, W. *, and Zhou, Y. * (2021) Hsa_circ_0004287 inhibits macrophage-mediated inflammation in an N6-methyladenosine-dependent manner in atopic dermatitis and psoriasis. Journal of Allergy and Clinical Immunology

• Li, Y., Chen, B., Zhao, J., Li, Q., Chen, S., Guo, T., Li, Y., Lai, H., Chen, Z., Meng, Z., Guo, W.*, He, X.*, and Huang, S.*（2021）HNRNPL Circularizes ARHGAP35 to Produce an Oncogenic Protein. Advanced Science n/a, 2001701

• Huang, R., Zhang, X., Li, W., Shang, L.*, Wang, H.*, and Zhao, Y.* (2021) Suction Cups-Inspired Adhesive Patch with Tailorable Patterns for Versatile Wound Healing. Advanced Science, e2100201-e2100201

• Zhao, C., Cai, L., Nie, M., Shang, L. *, Wang, Y. *, and Zhao, Y. * (2021) Cheerios Effect Inspired Microbubbles as Suspended and Adhered Oral Delivery Systems. Advanced Science 8, 2004184

• Zhao, D., Liu, W., Chen, K., Wu, Z., Yang, H.*, and Xu, Y.* (2021) Structure of the human RNA polymerase I elongation complex. Cell Discovery 7, 97

• Liang, L., Huan, L., Wang, J., Wu, Y., Huang, S., and He, X. * (2021) LncRNA RP11-295G20.2 regulates hepatocellular carcinoma cell growth and autophagy by targeting PTEN to lysosomal degradation. Cell Discovery 7, 118

• Wang, Y., Zhu, Y., Gu, Y., Ma, M., Wang, Y., Qi, S., Zeng, Y., Zhu, R., Wang, X., Yu, P., Xu, J., Shu, Y., and Yu, F.-X.* (2021) Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis. Cell Reports 36

• Mieradilijiang, A., Zhu, S., Yan, S., Xu, K., Zhang, J., Luo, S., Ma, W., Alam, M. F., Tang, Y., Huang, H., Chen, N., Wang, L., Yan, G., Li, J., Lai, H., Wang, C.*, Zhu, K.*, and Zhang, W.* (2021) Aorta smooth muscle-on-a-chip reveals impaired mitochondrial dynamics as a therapeutic target for aortic aneurysm in bicuspid aortic valve disease. eLife 10, e69310

• Huang, H., Lin, Y., Ma, W., Liu, J., Han, J., Hu, X., Tang, M., Yan, S., Abudupataer, M., Zhang, C., Gao, Q., and Zhang, W*. (2021) A pre-screening strategy to assess resected tumor margins by imaging cytoplasmic viscosity and hypoxia. eLife 10, e70471

• Wang, Q., Song, Y., Chen, J., Li, Q., Gao, J., Tan, H., Zhu, Y., Wang, Z., Li, M., Yang, H., Zhang, N., Li, X., Qian, J., Pang, Z., Huang, Z. *, and Ge, J.* (2021) Direct in vivo reprogramming with non-viral sequential targeting nanoparticles promotes cardiac regeneration. Biomaterials 276, 121028

• Wei, Z., Chen, Z., Zhao, Y., Fan, F., Xiong, W., Song, S., Yin, Y., Hu, J., Yang, K., Yang, L., Xu, B. *, and Ge, J.* (2021) Mononuclear phagocyte system blockade using extracellular vesicles modified with CD47 on membrane surface for myocardial infarction reperfusion injury treatment. Biomaterials 275, 121000

• Huang, W., Li, N., Zhang, Y., Wang, X., Yin, M., and Lei, Q.-Y. *(2021) AHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner. Autophagy, 1-11

• Chen, T., Ding, X., Liao, Q., Gao, N., Chen, Y., Zhao, C.*, Zhang, X.*, and Xu, J.* (2021) IL-21 arming potentiates the anti-tumor activity of an oncolytic vaccinia virus in monotherapy and combination therapy. Journal for ImmunoTherapy of Cancer 9,

• Li, C., Chi, H., Deng, S., Wang, H., Yao, H., Wang, Y., Chen, D., Guo, X., Fang, J.-Y., He, F., and Xu, J.* (2021) THADA drives Golgi residency and upregulation of PD-L1 in cancer cells and provides promising target for immunotherapy. Journal for ImmunoTherapy of Cancer 9, e002443

• He, H., Liao, Q., Zhao, C., Zhu, C., Feng, M., Liu, Z., Jiang, L., Zhang, L., Ding, X., Yuan, M*., Zhang, X.*, and Xu, J.* (2021) Conditioned CAR-T cells by hypoxia-inducible transcription amplification (HiTA) system significantly enhances systemic safety and retains antitumor efficacy. Journal for ImmunoTherapy of Cancer 9, e002755

• Li C, Yao H, Wang H, Fang JY, Xu J*. Repurposing screen identifies Amlodipine as an inducer of PD-L1 degradation and antitumor immunity. Oncogene. 2021 Feb;40(6):1128-1146

• Kong, S., Zhang, Q., Yang, L., Huang, Y., Liu, M., Yan, G., Zhao, H., Wu, M., Zhang, X., Yang, P. *, and Cao, W. * (2021) Effective Enrichment Strategy Using Boronic Acid-Functionalized Mesoporous Graphene–Silica Composites for Intact N- and O-Linked Glycopeptide Analysis in Human Serum. Analytical Chemistry 93, 6682-6691

• Shen, F., Xiong, Y., Zhang, L., Li, H., Zhao, H., Liu, X.*, and Yang, P.* (2021) Rapid Sample Preparation Workflow for Serum Sample Analysis with Different Mass Spectrometry Acquisition Strategies. Analytical Chemistry 93, 1578-1585

• Huang, Y., Zhang, Q., Yang, L., Lin, L., Xie, J., Yao, J., Zhou, X., Zhang, L., Shen, H. *, and Yang, P. * (2021) Puromycin-Modified Silica Microsphere-Based Nascent Proteomics Method for Rapid and Deep Nascent Proteome Profile. Analytical Chemistry 93, 6403-6413

• Wu, L., Fang, C., Zhang, L., Yuan, W., Yu, X.*, and Lu, H.* (2021) Integrated Strategy for Discovery and Validation of Glycated Candidate Biomarkers for Hemodialysis Patients with Cardiovascular Complications. Analytical Chemistry

• Cheng, M., Shu, H., Peng, Y., Feng, X., Yan, G., Zhang, L., Yao, J., Bao, H., and Lu, H.* (2021) Specific Analysis of α-2,3-Sialylated N-Glycan Linkage Isomers by Microchip Capillary Electrophoresis–Mass Spectrometry. Analytical Chemistry

• Wang, Z., Zhang, L., Yuan, W., Zhang, Y. *, and Lu, H. * (2021) SAPT, a Fast and Efficient Approach for Simultaneous Profiling of Protein N- and C-Terminome. Analytical Chemistry 93, 10553-10560

• Shao, Y., Bao, H., Ma, L., Yuan, W., Zhang, L., Yao, J., Meng, P., Peng, Y., Zhang, S., Cao, T., and Lu, H.* (2021) Enhancing Comprehensive Analysis of Newly Synthesized Proteins Based on Cleavable Bioorthogonal Tagging. Analytical Chemistry

• Feng, X., Shu, H., Zhang, S., Peng, Y., Zhang, L., Cao, X., Wei, L. *, and Lu, H. * (2021) Relative Quantification of N-Glycopeptide Sialic Acid Linkage Isomers by Ion Mobility Mass Spectrometry. Analytical Chemistry 93, 15617-15625

• Du, X., Cheng, X., Li, W., Ge, Z., Zhong, C., Fan, C., and Gu, H.* (2021) Engineering Allosteric Ribozymes to Detect Thiamine Pyrophosphate in Whole Blood. Analytical Chemistry

• Xu, T., Zhang, C., Xia, K., Li, W., Cao, Y. , and Gu, H. * (2021) Small DNAs that Bind Nickel(II) Specifically and Tightly. Analytical Chemistry 93, 14912-14917

• He, S., Wu, Z., Tian, Y., Yu, Z., Yu, J., Wang, X., Li, J., Liu, B., and Xu, Y. *(2020) Structure of nucleosome-bound human BAF complex.Science 367, 875-881

• Zheng, H., Qi, Y., Hu, S., Cao, X., Xu, C., Yin, Z., Chen, X., Li, Y., Liu, W., Li, J., Wang, J., Wei, G., Liang, K., Chen, F. X.*, and Xu, Y.* (2020) Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase. Science 370, eabb5872
  

• Li, J.-T., Yin, M., Wang, D., Wang, J., Lei, M.-Z., Zhang, Y., Liu, Y., Zhang, L., Zou, S.-W., Hu, L.-P., Zhang, Z.-G., Wang, Y.-P., Wen, W.-Y., Lu, H.-J., Chen, Z.-J., Su, D., and Lei, Q.-Y.* (2020) BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma. Nature Cell Biology 22, 167-174

• Xu GL*, Bochtler M*. Reversal of nucleobase methylation by dioxygenases. Nat Chem Biol. 2020 Nov;16(11):1160-1169. 
  

• Huang, Y., Wang, H., Hao, Y., Lin, H., Dong, M., Ye, J., Song, L., Wang, Y., Li, Q., Shan, B., Jiang, Y., Li, H., Shao, Z., Kroemer, G., Zhang, H., Bai, L., Jin, T., Wang, C., Ma, Y., Cai, Y., Ding, C., Liu, S.*, Pan, Y.*, Jiang, W.*, and Zhou, R.* (2020) Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity. Nature Cell Biology

• Qin, Y., Chen, W., Jiang, G., Zhou, L., Yang, X., Li, H., He, X., Wang, H.-l., Zhou, Y.-b., Huang, S., and Liu, S.* (2020) Interfering MSN-NONO complex–activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer. Science Advances 6, eaaw9960

• Jiao, F., Li, Z., He, C., Xu, W., Yang, G., Liu, T., Shen, H., Cai, J., Anastas, J. N., Mao, Y., Yu, Y., Lan, F., Shi, G. Y., Jones, C., Xu, Y., Baker, S.*, Shi, Y.*, and Guo, R.* (2020) RACK7 recognizes H3. 3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma. Science Advances 6, eaba2113

• Li, W., Karwacki-Neisius, V., Ma, C., Tan, L., Shi, Y., Wu, F.*, and Shi, Y. G.* (2020) Nono deficiency compromises TET1 chromatin association and impedes neuronal differentiation of mouse embryonic stem cells. Nucleic Acids Research

• Li S, Feng J, Wu F*, Cai J, Zhang X, Wang H, Fetahu IS, Iwanicki I, Ma D, Hu T, Liu H, Wang B, Shi G, Tan L*, Shi YG.* TET2 promotes anti-tumor immunity by governing G-MDSCs and CD8+ T-cell numbers. EMBO Rep. 2020 Sep 14;21(10):e49425.

• Chen, Y., Lyu, R., Rong, B., Zheng, Y., Lin, Z., Dai, R., Zhang, X., Xie, N., Wang, S., Tang, F.*, Lan, F.*, and Tong, M.-H.* (2020) Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks. Cell Research

• Wan, J., Xing, S., Ding, L., Wang, Y., Gu, C., Wu, Y., Rong, B., Li, C., Wang, S., Chen, K., He, C., Zhu, D., Yuan, S., Qiu, C., Zhao, C., Nie, L., Gao, Z., Jiao, J., Zhang, X., Wang, X., Ying, T., Wang, H., Xie, Y.*, Lu, Y.*, Xu, J.*, and Lan, F.* (2020) Human-IgG-Neutralizing Monoclonal Antibodies Block the SARS-CoV-2 Infection. Cell Reports 32, 107918-107918

• Liu, Z., Yang, Y., Gu, A., Xu, J., Mao, Y., Lu, H., Hu, W., Lei, Q.-Y., Li, Z., Zhang, M., Cai, Yu.*, and Wen, W.* (2020) Par complex cluster formation mediated by phase separation. Nature Communications 11, 1-18

• Tang, D.-J., Du, X., Shi, Q., Zhang, J.-L., He, Y.-P., Chen, Y.-M., Ming, Z., Wang, D., Zhong, W.-Y., Liang, Y.-W., Liu, J.-Y., Huang, J.-M., Zhong, Y.-S., An, S.-Q., Gu, H.*, and Tang, J.-L.* (2020) A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA. Nature Communications 11, 2794

• Xia K, Shen J, Li Q, Fan C*, Gu H*. Near-Atomic Fabrication with Nucleic Acids. ACS Nano. 2020 Feb 25;14(2):1319-1337.

• Zhang, W., Xu, L., Park, H.-B., Hwang, J., Kwak, M., Lee, P. C., Liang, G., Zhang, X., Xu, J., and Jin, J.-O.* (2020) Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy. Nature Communications 11, 1-14

• Yang, Y., Liu, X., Shen, C., Lin, Y., Yang, P., and Qiao, L.* (2020) In silico spectral libraries by deep learning facilitate data-independent acquisition proteomics. Nature Communications 11, 1-11
  

• Li, Y., Li, J., Wang, R., Zhang, L., Fu, G., Wang, X., Wang, Y., Fang, C., Zhang, D., Du, D., Ma, X., Pan, M., Guo, Q., Xu, X., Hu, X., Zhou, Y., Mo, S., Wang, H., Gao, J., Huang, S., Liu, Y., Cai, S., Hua, G.*, Peng, J.*, and Yu, F.-X.* (2020) Frequent RNF43 mutation contributes to moderate activation of Wnt signaling in colorectal signet-ring cell carcinoma. Protein & Cell

• Xu, D., Yang, M., Capitano, M., Guo, B., Liu, S., Wan, J., Broxmeyer, H. E.*, and Huang, X.* (2020) Pharmacological activation of nitric oxide signaling promotes human hematopoietic stem cell homing and engraftment. Leukemia, 1-6

•  Qu, R., Dong, L., Zhang, J., Yu, X., Wang, L.*, and Zhu, S.* (2020). Cryo-EM structure of human heptameric Pannexin 1 channel. Cell Research, 1-3.

• Zheng, W., Zhou, Z., Sha, Q., Niu, X., Sun, X., Shi, J., Zhao, L., Zhang, S., Dai, J., Cai, S., Meng, F., Hu, L., Gong, F., Li, X., Fu, J., Shi, R., Lu, G., Chen, B., Fan, H., Wang, L., Lin, G.*, and Sang, Q.* (2020) Homozygous Mutations in BTG4 Cause Zygotic Cleavage Failure and Female Infertility. The American Journal of Human Genetics 107, 1-10

• Zhang, Z., Li, B., Fu, J., Li, R., Diao, F., Li, C., Chen, B., Du, J., Zhou, Z., Mu, J., Yan, Z., Wu, L., Liu, S., Wang, W., Zhao, L., Dong, J., He, L., Liang, X., Kuang, Y., Sun, X., Sang, Q.*, and Wang, L.* (2020) Bi-allelic Missense Pathogenic Variants in TRIP13 Cause Female Infertility Characterized by Oocyte Maturation Arrest. American Journal of Human Genetics 107, 15-23

• Zhao, L., Xue, S., Yao, Z., Shi, J., Chen, B., Wu, L., Sun, L., Xu, Y., Yan, Z., Li, B., Mao, X., Fu, J., Zhang, Z., Mu, J., Wang, W., Du, J., Liu, S., Dong, J., Wang, W., Li, Q., He, L., Jin, L., Liang, X., Kuang, Y., Sun, X., Wang, L.*, and Sang, Q.* (2020) Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development. Protein & Cell

• Ding, J., Zhao, J., Huan, L., Liu, Y., Qiao, Y., Wang, Z., Chen, Z., Huang, S., Zhao, Y.*, and He, X.* (2020) Inflammation-induced LINC00665 increases the malignancy through activating PKR/NF-kappa B pathway in hepatocellular carcinoma.Hepatology. 2020 Feb 21.

• Li Z, Lu X, Liu Y, Zhao J, Ma S, Yin H, Huang S, Zhao Y*, He X*. Gain of LINC00624 Enhances Liver Cancer Progression by Disrupting the HDAC6-TRIM28-ZNF354C Corepressor Complex. Hepatology. 2020 Sep 1.

• Wu, Y. J., Zhao, Y. M., Huan, L., Zhao, J. J., Zhou, Y. Q., Xu, L. G., Hu, Z. X., Liu, Y. Z., Chen, Z. A., Wang, L., Huang, S. L.*, He, X. H.*, and Liang, L. H.* (2020) An LTR Retrotransposon-Derived Long Noncoding RNA lncMER52A Promotes Hepatocellular Carcinoma Progression by Binding p120-Catenin. Cancer Res. 80, 976-987

• Huan, L., Guo, T., Wu, Y., Xu, L., Huang, S., Xu, Y.*, Liang, L.*, and He, X.* (2020) Hypoxia induced LUCAT1/PTBP1 axis modulates cancer cell viability and chemotherapy response. Molecular Cancer 19

• Xu L, Huan L, Guo T, Wu Y, Liu Y, Wang Q, Huang S, Xu Y*, Liang L*, He X*. LncRNA SNHG11 facilitates tumor metastasis by interacting with and stabilizing HIF-1α. Oncogene. 2020 Oct 15.

• Mei, X.*, Qi, D., Zhang, T., Zhao, Y., Jin, L., Hou, J., Wang, J., Lin, Y., Xue, Y., Zhu, P., Liu, Z., Huang, L., Nie, J., Si, W., Ma, J., Ye, J., Finnell, R., H , Saiyin, H., Wang, H.*, Zhao, J.*, Zhao, S.*, and Xu, W.*(2020) Inhibiting MARSs reduces hyperhomocysteinemia‐associated neural tube and congenital heart defects. EMBO Molecular Medicine

• Xia, Y.-K., Zeng, Y.-R., Zhang, M.-L., Liu, P., Liu, F., Zhang, H., He, C.-X., Sun, Y.-P., Zhang, J.-Y., Zhang, C., Song, L., Ding, C., Tang, Y.-J., Yang, Z., Yang, C., Wang, P., Guan, K.-L., Xiong, Y., and Ye, D.* (2020) Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network. Protein & Cell

• Cheng, Z.-L., Zhang, M.-L., Lin, H.-P., Gao, C., Song, J.-B., Zheng, Z., Li, L., Zhang, Y., Shen, X., Zhang, H., Huang, Z., Zhan, W., Zhang, C., Hu, X., Sun, Y.-P., Jiang, L., Sun, L., Xu, Y., Yang, C., Ge, Y., Zhao, Y., Liu, X., Yang, H., Liu, P., Guo, X., Guan, K.-L., Xiong, Y., Zhang, M., and Ye, D.* (2020) The Zscan4-Tet2 Transcription Nexus Regulates Metabolic Rewiring and Enhances Proteostasis to Promote Reprogramming. Cell Reports 32, 107877-107877

• Xia, L., Wang, X., Liu, L., Fu, J., Xiao, W., Liang, Q., Han, X., Huang, S., Sun, L., Gao, Y., Zhang, C., Yang, L., Wang, L., Qian, L.*, and Zhou, Y.* (2020) Lnc-BAZ2B promotes M2 macrophage activation and inflammation in asthmatic children through stabilizing BAZ2B pre-mRNA. Journal of Allergy and Clinical Immunology

• Liu, H. Y., Liu, Y. Y., Yang, F., Zhang, L., Zhang, F. L., Hu, X., Shao, Z. M.*, and Li, D. Q.* (2020) Acetylation of MORC2 by NAT10 regulates cell-cycle checkpoint control and resistance to DNA-damaging chemotherapy and radiotherapy in breast cancer. Nucleic Acids Research 48, 3638-3656

• Sun, W., Zhang, X., Chen, D.*, and Murchie, A. I.* (2020) Interactions between the 5′ UTR mRNA of the spe2 gene and spermidine regulate translation in S. pombe. RNA 26, 137-149

• Zhang, X., Sun, W., Chen, D.*, and Murchie, A. I.* (2020) Interactions between SAM and the 5′ UTR mRNA of the sam1 gene regulate translation in S. pombe. RNA 26, 150-161

• Zhang J, Liu G, Sun W, Chen, D.*, and Murchie, A. I.* The effects of aminoglycoside antibiotics on twister ribozyme cleavage. FEBS J. 2020 Aug 13
  

• Ma, H., Wang, X., Cai, J., Dai, Q., Natchiar, S. K., Lv, R., Chen, K., Lu, Z., Chen, H., Shi, Y. G., Lan, F., Fan, J., Klaholz, B. P., Pan, T., Shi, Y., and He, C. (2019) N-6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation. Nature Chemical Biology 15, 88-94

• Huo, X., Ji, L., Zhang, Y., Lv, P., Cao, X., Wang, Q., Yan, Z., Dong, S., Du, D., Zhang, F., Wei, G., Liu, Y., and Wen, B. (2019) The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation. Molecular Cell 77, 368-383. e367
  

• Chen, H., Yu, D., Fang, R., Rabidou, K., Wu, D., Hu, D., Jia, P., Zhao, Z., Wu, Z., Peng, J., Shi, Y., and Shi, Y. G. (2019) TET2 stabilization by 14-3-3 binding to the phosphorylated Serine 99 is deregulated by mutations in cancer. Cell research

•  Li, J., Li, Y., Li, W., Luo, H., Xi, Y., Dong, S., Gao, M., Xu, P., Zhang, B., Liang, Y., Zou, Q., Hu, X., Peng, L., Zou, D., Wang, T., Yang, H., Jiang, C., Peng, S., Wu, F., and Yu, W. (2019) Guide Positioning Sequencing identifies aberrant DNA methylation patterns that alter cell identity and tumor-immune surveillance networks. Genome Research 29, 270-280
  

• Wang, L., Zhou, Y., Chen, Z., Sun, L., Wu, J., Li, H., Liu, F., Wang, F., Yang, C., Yang, J., Leng, Q., Zhang, Q., Xu, A., Shen, L., Sun, J., Wu, D., Fang, C., Lu, H., Yan, D., and Ge, B. (2019) PLC beta 2 negatively regulates the inflammatory response to virus infection by inhibiting phosphoinositide-mediated activation of TAK1. Nature Communications 10
  

• Liu, Y., Fu, Y., Wang, Q., Li, M., Zhou, Z., Dabbagh, D., Fu, C., Zhang, H., Li, S., Zhang, T., Gong, J., Kong, X., Zhai, W., Su, J., Sun, J., Zhang, Y., Yu, X.-F., Shao, Z., Zhou, F., Wu, Y., and Tan, X. (2019) Proteomic profiling of HIV-1 infection of human CD4(+) T cells identifies PSGL-1 as an HIV restriction factor. Nat Microbiol 4, 813-825
  

• Sang, Q., Zhang, Z., Shi, J., Sun, X., Li, B., Yan, Z., Xue, S., Ai, A., Lyu, Q., Li, W., Zhang, J., Wu, L., Mao, X., Chen, B., Mu, J., Li, Q., Du, J., Sun, Q., Jin, L., He, L., Zhu, S., Kuang, Y., and Wang, L. (2019) A pannexin 1 channelopathy causes human oocyte death. Science Translational Medicine 11
  

• Fang, C., Li, J., Qi, S., Lei, Y., Zeng, Y., Yu, P., Hu, Z., Zhou, Y., Wang, Y., Dai, R., Li, J., Huang, S., Xu, P., Chen, K., Ding, C., and Yu, F.-X. (2019) An alternatively transcribed TAZ variant negatively regulates JAK-STAT signaling. EMBO Reports 20
  

• Li, Y., Yao, C.-F., Xu, F.-J., Qu, Y.-Y., Li, J.-T., Lin, Y., Cao, Z.-L., Lin, P.-C., Xu, W., Zhao, S.-M., and Zhao, J.-Y. (2019) APC/C-CDH1 synchronizes ribose-5-phosphate levels and DNA synthesis to cell cycle progression. Nature Communications 10
  

• Jin, X., Xu, X.-E., Jiang, Y.-Z., Liu, Y.-R., Sun, W., Guo, Y.-J., Ren, Y.-X., Zuo, W.-J., Hu, X., Huang, S.-L., Shen, H.-J., Lan, F., He, Y.-F., Hu, G.-H., Di, G.-H., He, X.-H., Li, D.-Q., Liu, S., Yu, K.-D., and Shao, Z.-M. (2019) The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation. Science Advances 5
  

• Wang, Z., Liu, Z., Chen, X., Li, J., Yao, W., Huang, S., Gu, A., Lei, Q.-Y., Mao, Y., and Wen, W. (2019) A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases. Nature Communications 10
  

• Zheng, Q., Zhao, J., Yu, H., Zong, H., He, X., Zhao, Y., Li, Y., Wang, Y., Bao, Y., Li, Y., Chen, B., Guo, W., Wang, Y., Chen, Z., Zhao, Y., Wang, L., He, X., and Huang, S. (2019) Tumor-Specific Transcripts Are Frequently Expressed in Hepatocellular Carcinoma With Clinical Implication and Potential Function. Hepatology
  

• Li, Z., Wang, Z., Tang, Y., Lu, X., Chen, J., Dong, Y., Wu, B., Wang, C., Yang, L., Guo, Z., Xue, M., Lu, S., Wei, W., and Shi, Q. (2019) Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics. Nature Communications 10, 3856-3856
  

• Xiao, J., Liu, M., Qi, Y., Chaban, Y., Gao, C., Pan, B., Tian, Y., Yu, Z., Li, J., Zhang, P., and Xu, Y. (2019) Structural insights into the activation of ATM kinase. Cell Research 29, 683-685
  

• Fetahu, I. S., Ma, D., Rabidou, K., Argueta, C., Smith, M., Liu, H., ... & Shi, Y. G. (2019). Epigenetic signatures of methylated DNA cytosine in Alzheimer’s disease. Science Advances, 5(8), eaaw2880.
  

• Li, P., Ge, J., and Li, H. (2019) Lysine acetyltransferases and lysine deacetylases as targets for cardiovascular disease. Nature Reviews. Cardiology
  

• Zhang, Y.-Z., Chen, Y.-M., Wang, W., Qin, X.-C., and Holmes, E. C. (2019) Expanding the RNA Virosphere by Unbiased Metagenomics. Annual review of virology
  

• Wu, D., Hu, D., Chen, H., Shi, G., Fetahu, I. S., Wu, F., Rabidou, K., Fang, R., Tan, L., Xu, S., Liu, H., Argueta, C., Zhang, L., Mao, F., Yan, G., Chen, J., Dong, Z., Lv, R., Xu, Y., Wang, M., Ye, Y., Zhang, S., Duquette, D., Geng, S., Yin, C., Lian, C. G., Murphy, G. F., Adler, G. K., Garg, R., Lynch, L., Yang, P., Li, Y., Lan, F., Fan, J., Shi, Y., and Shi, Y. G. (2018) Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer. Nature 559, 637-641
  

• Hu, Q., Li, H., Wang, L., Gu, H., and Fan, C. (2018) DNA Nanotechnology-Enabled Drug Delivery Systems. Chemical reviews
  

• Yu, L., Yang, G., Zhang, X., Wang, P., Weng, X., Yang, Y., Li, Z., Fang, M., Xu, Y., Sun, A., and Ge, J. (2018) Megakaryocytic Leukemia 1 Bridges Epigenetic Activation of NADPH Oxidase in Macrophages to Cardiac Ischemia-Reperfusion Injury. Circulation 138, 2820-2836
  

• Chen, X., Liu, M., Tian, Y., Li, J., Qi, Y., Zhao, D., Wu, Z., Huang, M., Wong, C. C. L., Wang, H.-W., Wang, J., Yang, H., and Xu, Y. (2018) Cryo-EM structure of human mTOR complex 2. Cell Research 28, 518-528
  

•  Feng, Y., Tian, Y., Wu, Z., and Xu, Y. (2018) Cryo-EM structure of human SRCAP complex. Cell Research
  

• Zhao, B., Xu, W., Rong, B., Chen, G., Ye, X., Dai, R., Li, W., Chen, J., Cai, J., Song, L., Luo, Z.-Q., Zeng, R., Shi, Y., Han, J.-D. J., and Lan, F. (2018) H3K14me3 genomic distributions and its regulation by KDM4 family demethylases. Cell Research
  

• Qian, M., Xu, H., Perez-Andreu, V., Roberts, K. G., Zhang, H., Yang, W., Zhang, S., Zhao, X., Smith, C., and Devidas, M. J. B. (2018) Novel susceptibility variants at the ERG locus for childhood acute lymphoblastic leukemia in Hispanics. Blood-2018-2007-862946
  

• Wang, J., Yu, Y., Li, G., Shen, C., Meng, Z., Zheng, J., Jia, Y., Chen, S., Zhang, X., Zhu, M., Zheng, J., Song, Z., Wu, J., Shao, L., Qian, P., Mao, X., Wang, X., Huang, Y., Zhao, C., Zhang, J., Qiu, C., and Zhang, W. (2018) Relationship between serum HBV-RNA levels and intrahepatic viral as well as histologic activity markers in entecavir-treated patients. Journal of Hepatology 68, 16-24
  

• Zhilei Ge||; Hongzhou Gu||; Qian Li; Chunhai Fan*. “Concept and Development of Framework Nucleic Acids.” Journal of the American Chemical Society 2018, doi: 10.1021/jacs.8b10529. 
  

• Wen, J., Lv, R., Ma, H., Shen, H., He, C., Wang, J., Jiao, F., Liu, H., Yang, P., Tan, L., Lan, F., Shi, Y. G., He, C., Shi, Y., and Diao, J. (2018) Zc3h13 Regulates Nuclear RNA m(6)A Methylation and Mouse Embryonic Stem Cell Self-Renewal. Molecular Cell 69, 1028-1038
  

• Chen, J., Yang, Y. F., Yang, Y., Zou, P., Chen, J., He, Y. Q., Shui, S. L., Cui, Y. R., Bai, R., Liang, Y. J., Hu, Y. W., Jiang, B., Lu, L., Zhang, X. Y., Liu, J., and Xu, J. Q. (2018) AXL promotes Zika virus infection in astrocytes by antagonizing type I interferon signalling. Nat Microbiol 3, 302-309
  

• Li, S., Hu, Z., Zhao, Y., Huang, S., and He, X. (2018) Transcriptome-Wide Analysis Reveals the Landscape of Aberrant Alternative Splicing Events in Liver Cancer. Hepatology
  

• Yu J#, Luo Y#, Zhu Z#, Zhou Y#, Sun L, Gao J, Sun J, Wang G, Yao X*, Li W*.A tryptophan metabolite of the skin microbiota attenuates inflammation in atopic dermatitis via the aryl hydrocarbon receptor. J Allergy Clin Immunol. 2018 Dec 19. pii: S0091-6749(18)32777-5. doi: 10.1016/j.jaci.2018.11.036.
  

• Hu, J., Li, W., Adebali, O., Yang, Y., Oztas, O., Selby, C. P., & Sancar, A. (2018). Genome-wide mapping of nucleotide excision repair with XR-seq. Nature protocols, 1. 
  

• Li, F.-L., Liu, J.-P., Bao, R.-X., Yan, G., Feng, X., Xu, Y.-P., Sun, Y.-P., Yan, W., Ling, Z.-Q., Xiong, Y., Guan, K.-L., and Yuan, H.-X. (2018) Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis. Nature Communications 9
  

• Shan, Z., Tu, Y., Yang, Y., Liu, Z., Zeng, M., Xu, H., Long, J., Zhang, M., Cai, Y., and Wen, W. (2018) Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division. Nature Communications 9
  

• Wang, Z., Zhu, L., Nguyen, T. H. O., Wan, Y., Sant, S., Quinones-Parra, S. M., Crawford, J. C., Eltahla, A. A., Rizzetto, S., Bull, R. A., Qiu, C., Koutsakos, M., Clemens, E. B., Loh, L., Chen, T., Liu, L., Cao, P., Ren, Y., Kedzierski, L., Kotsimbos, T., McCaw, J. M., La Gruta, N. L., Turner, S. J., Cheng, A. C., Luciani, F., Zhang, X., Doherty, P. C., Thomas, P. G., Xu, J., and Kedzierska, K. (2018) Clonally diverse CD38(+)HLA-DR(+)CD8(+) T cells persist during fatal H7N9 disease. Nature Communications 9
  

• Qiu, T., Yang, Y., Qiu, J., Huang, Y., Xu, T., Xiao, H., Wu, D., Zhang, Q., Zhou, C., Zhang, X., Tang, K., Xu, J., and Cao, Z. (2018) CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens. Nature Communications 9
  

• Li, Z., Zhang, J., Liu, X., Li, S., Wang, Q., Chen, D., Hu, Z., Yu, T., Ding, J., Li, J., Yao, M., Fan, J., Huang, S., Gao, Q., Zhao, Y., and He, X. (2018) The LINCO1138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma. Nature Communications 9
  

• Liu, Y., Guo, J. Z., Liu, Y., Wang, K., Ding, W., Wang, H., Liu, X., Zhou, S., Lu, X. C., Yang, H. B., Xu, C., Gao, W., Zhou, L., Wang, Y. P., Hu, W., Wei, Y., Huang, C., and Lei, Q. Y. (2018) Nuclear lactate dehydrogenase A senses ROS to produce alpha-hydroxybutyrate for HPV-induced cervical tumor growth. Nature Communications 9, 4429
  

• Zhu, X., Li, J., Qiu, X., Liu, Y., Feng, W., and Li, F. (2018) Upconversion nanocomposite for programming combination cancer therapy by precise control of microscopic temperature. Nature Communications 9
  

• Zhang, Q., Bai, B., Mei, X., Wan, C., Cao, H., Li, D., Wang, S., Zhang, M., Wang, Z., Wu, J., Wang, H., Huo, J., Ding, G., Zhao, J., Xie, Q., Wang, L., Qiu, Z., Zhao, S., and Zhang, T. (2018) Elevated H3K79 homocysteinylation causes abnormal gene expression during neural development and subsequent neural tube defects. Nature Communications 9
  

• Liu, J., Duan, Z., Guo, W., Zeng, L., Wu, Y., Chen, Y., Tai, F., Wang, Y., Lin, Y., Zhang, Q., He, Y., Deng J., Stewart, R., Wang, C., Lin, P., Ghaffari, S., Evers, B.M., Liu, S.*, Zhou, M-M.*, Zhou, B.*, and Shi, J.*. Targeting the BRD4/FOXO3a/CDK6 axis Sensitizes AKT Inhibition in Luminal Breast Cancer. Nature Communications 9:5200, 2018. 
  

• Wang, Y., Song, L., Liu, M., Ge, R., Zhou, Q., Liu, W., Li, R., Qie, J., Zhen, B., Wang, Y., He, F., Qin, J., and Ding, C. (2018) A proteomics landscape of circadian clock in mouse liver. Nature Communications 9
  

• Dang, T., Duan, W. Y., Yu, B., Tong, D. L., Cheng, C., Zhang, Y. F., Wu, W., Ye, K., Zhang, W. X., Wu, M., Wu, B. B., An, Y., Qiu, Z. L., and Wu, B. L. (2018) Autism-associated  Dyrk1a truncation mutants impair neuronal dendritic and spine growth and interfere with postnatal cortical development. Molecular Psychiatry 23, 747-758
  

• Xinyu Du; Xin Zhong; Wei Li; Hua Li*; Hongzhou Gu*. “Retraining and Optimizing DNA-Hydrolyzing Deoxyribozymes for Robust Single- and Multiple-Turnover Activities.” ACS Catalysis 2018, 8, 5996-6005.
  

• Chen, W., Qin, Y., Wang, D., Zhou, L., Liu, Y., Chen, S., Yin, L., Xiao, Y., Yao, X.-H., Yang, X., Ma, W., Chen, W., He, X., Zhang, L., Yang, Q., Bian, X., Shao, Z.-m., and Liu, S. (2018) CCL20 triggered by chemotherapy hinders the therapeutic efficacy of breast cancer. PLoS Biology 16
  

• Zhang, F. L., Cao, J. L., Xie, H. Y., Sun, R., Yang, L. F., Shao, Z. M., & Li, D. Q. (2018). Cancer-Associated MORC2-Mutant M276I Regulates an hnRNPM-Mediated CD44 Splicing Switch to Promote Invasion and Metastasis in Triple-Negative Breast Cancer. Cancer research, 78(20), 5780-5792. 
  

• Sun, R., Xie, H.-Y., Qian, J.-X., Huang, Y.-N., Yang, F., Zhang, F.-L., Shao, Z.-M., and Li, D.-Q. (2018) FBXO22 Possesses Both Protumorigenic and Antimetastatic Roles in Breast Cancer Progression. Cancer Research 78, 5274-5286
  

• Chen, X.-F., Tian, M.-X., Sun, R.-Q., Zhang, M.-L., Zhou, L.-S., Jin, L., Chen, L.-L., Zhou, W.-J., Duan, K.-L., Chen, Y.-J., Gao, C., Cheng, Z.-L., Wang, F., Zhang, J.-Y., Sun, Y.-P., Yu, H.-X., Zhao, Y.-Z., Yang, Y., Liu, W.-R., Shi, Y.-H., Xiong, Y., Guan, K.-L., and Ye, D. (2018) SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer. EMBO Reports 19
  

• Yan, W.-W., Liang, Y.-L., Zhang, Q.-X., Wang, D., Lei, M.-Z., Qu, J., He, X.-H., Lei, Q.-Y., and Wang, Y.-P. (2018) Arginine methylation of SIRT7 couples glucose sensing with mitochondria biogenesis. EMBO Reports
  

• Guo, W., Hu, Z., Bao, Y., Li, Y., Li, S., Zheng, Q., Lyu, D., Chen, D., Yu, T., Li, Y., Zhu, X., Ding, J., Zhao, Y., He, X. H., & Huang, S. (2018). A LIN28B Tumor-Specific Transcript in Cancer. Cell Reports, 22(8), 2016-2025. 
  

• Wang, D., Zhao, R., Qu, Y. Y., Mei, X. Y., Zhang, X., Zhou, Q., Li, Y., Yang, S. B., Zuo, Z. G., Chen, Y. M., Lin, Y., Xu, W., Chen, C., Zhao, S. M., and Zhao, J. Y. (2018) Colonic Lysine Homocysteinylation Induced by High-Fat Diet Suppresses DNA Damage Repair. Cell Reports 25, 398-412 e396
  

• Zhong, X. Y., Yuan, X. M., Xu, Y. Y., Yin, M., Yan, W. W., Zou, S. W., Wei, L. M., Lu, H. J., Wang, Y. P., and Lei, Q. Y. (2018) CARM1 Methylates GAPDH to Regulate Glucose Metabolism and Is Suppressed in Liver Cancer. Cell Reports 24, 3207-3223
  

• Chen, L.-L., Lin, H.-P., Zhou, W.-J., He, C.-X., Zhang, Z.-Y., Cheng, Z.-L., Song, J.-B., Liu, P., Chen, X.-Y., Xia, Y.-K., Chen, X.-F., Sun, R.-Q., Zhang, J.-Y., Sun, Y.-P., Song, L., Liu, B.-J., Du, R.-K., Ding, C., Lan, F., Huang, S.-L., Zhou, F., Liu, S., Xiong, Y., Ye, D., and Guan, K.-L. (2018) SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response. Cell Reports 25
  

• Zhao, C., and Xu, J. (2018) Toward universal influenza virus vaccines: from natural infection to vaccination strategy. Current Opinion in Immunology 53, 1-6
  

• Ye, D., Guan, K.-L., and Xiong, Y. (2018) Metabolism, Activity, and Targeting of D- and L-2-Hydroxyglutarates. Trends in Cancer 4, 151-165
  

• Zhang, Y., Peng, Y., Yang, L. J., and Lu, H. J. (2018) Advances in sample preparation strategies for MS-based qualitative and quantitative N-glycomics. Trends in Analytical Chemistry  99, 34-46. 
  

• Zhu XJ, Su QQ, Feng W, Li FY. Anti-Stokes shift luminescent materials for bio-applications. Chem Soc Rev. 2017 Feb 21;46(4):1025-1039.

• Hou G, Chen L, Liu G, Li L, Yang Y, Yan HX, Zhang HL, Tang J, Yang YC, Lin X, Chen X, Luo GJ, Zhu Y, Tang S, Zhang J, Liu H, Gu Q, Zhao LH, Li Y, Liu L, Zhou W, Wang H. Aldehyde dehydrogenase-2 (ALDH2) opposes hepatocellular carcinoma progression by regulating AMP-activated protein kinase signaling in mice. Hepatology. 2017 May; 65(5):1628-1644.

• Xia S, Lin R, Jin L, Zhao L, Kang HB, Pan Y, Liu S, Qian G, Qian Z, Konstantakou E, Zhang B, Dong JT, Chung YR, Abdel-Wahab O, Merghoub T, Zhou L, Kudchadkar RR, Lawson DH, Khoury HJ, Khuri FR, Boise LH, Lonial S, Lee BH, Pollack BP, Arbiser JL, Fan J, Lei QY, Chen J. Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth. Cell Metab. 2017 Feb 7;25(2):358-373.

• Ma LL, Ge JB, Sun AJ. Letter by Ma et al Regarding Article, "Induction of Therapeutic Hypothermia During Out-of-Hospital Cardiac Arrest Using a Rapid Infusion of Cold Saline: The RINSE Trial (Rapid Infusion of Cold Normal Saline)". Circulation, 2017;135(8):e92-e93

• Yang G, Weng X, Zhao Y, Zhang X, Hu Y, Dai X, Liang P, Wang P, Ma L, Sun X, Hou L, Xu H, Fang M, Li Y, Jenuwein T, Xu Y, Sun A. The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction. Nat Commun. 2017;8: 14941

• Wu S, Wang D, Liu J, Feng Y, Weng J, Gao X, Liu J, Wang W. The Dynamic Multisite Interactions between Two Intrinsically Disordered Proteins. Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7515-7519.

• Wang D, Wang F, Shi KH, Tao H, Li Y, Zhao R, Lu H, Duan W, Qiao B, Zhao SM, Wang HY, Zhao JY. Lower Circulating Folate Induced by a Fidgetin Intronic Variant Is Associated With Reduced Congenital Heart Disease Susceptibility. Circulation. 2017 May 2; 135:1733-1748.

• Huang A, Zhao X, Yang XR, Li FQ, Zhou XL, Wu K, Zhang X, Sun QM, Cao Y, Zhu HM, Wang XD, Yang HM, Wang J, Tang ZY, Hou Y, Fan J, Zhou J(correspondence author). Circumventing intratumoral heterogeneity to identify potential therapeutic targets in hepatocellular carcinoma. J Hepatol. 2017 Aug;67(2):293-301.

• Fu Y, Wu P, Pan Y, Sun X,Yang H, Difiglia M, Lu B. A toxic mutant huntingtin species is resistant to selective autophagy. Nat Chem Biol. 2017 Nov;13(11):1152-1154.

• Shengli Li, Yuchen Li, Bing Chen, Jingjing Zhao, Shulin Yu, Yan Tang, Qiupeng Zheng, Yan Li, Peng Wang, Xianghuo He , Shenglin Huang*. exoRBase: a database of circRNA, lncRNA and mRNA in human blood exosomes. Nucleic Acids Research. 2017 Oct 9.. gkx891

• Tao Yu*, Yingjun Zhao*, Zhixiang Hu, Jing Li, Dandan Chu1 Jiwei Zhang, Zhe Li, Bing Chen, Xiao Zhang, Hongyu Pan, Shengli Li, Hechun Lin, Lei Liu, Mingxia Yan, Xianghuo He*†, andMing Yao *†. MetaLnc9 Facilitates Lung Cancer Metastasis via a PGK1-Activated AKT/mTOR Pathway. Cancer Research. 2017 Nov 1;77(21):5782-5794. doi: 10.1158/0008-5472.CAN-17-0671.  

• Jiwei Zhang*, Zhe Li*, Longzi Liu*, Qifeng Wang, Shengli Li, Di Chen, Zhixiang Hu, Tao Yu, Jie Ding, Jinjun Li, Ming Yao, Shenglin Huang, Yingjun Zhao*,Xianghuo He1*. Long Noncoding RNA TSLNC8 Is a Tumor Suppressor that Inactivates the IL-6/STAT3 Signaling Pathway. Hepatology.2017 Jul 26. doi: 10.1002/hep.29405. [Epub ahead of print]

• Liu MQ, Zeng WF, Fang P, Cao WQ, Liu C, Yan GQ, Zhang Y,Peng C, Wu JQ, Zhang XJ, Tu HJ, Chi H,  Sun RX, Cao Y,Dong MQ, Jiang BY, Huang JM, Shen HL, Wong CC*,  He SM*. Yang PY*. pGlyco 2.0 enables precision N-glycoproteomics with comprehensive quality control and one-step mass spectrometry for intact glycol-peptide identification. Nature Communications 2017,8: 438   

• Wang F, Wang K, Xu W, Zhao S, Ye D, Wang Y, Xu Y, Zhou L, Chu Y, Zhang C, Qin X, Yang PY*, and Yu H*. (2017) SIRT5 desuccinylates and activates pyruvate kinase M2 to block macrophage IL-1β production and to prevent DSS-induced colitis in mice. Cell Reports, 19: 2331–2344.

• Lin L, Ding Y, Wang Y, Wang Z, Yin X, Yan G, Zhang L, Yang PY*, Shen H*. (2017) Functional lipidomics: palmitic acid impairs hepatocellular carcinoma development by modulating membrane fluidity and glucose metabolism. Hepatology, 66(2):432-448.

• Gao X, Lin SH, Ren F, Li JT, Chen JJ, Yao CB, Yang HB, Jiang SX, Yan GQ, Wang D, Wang Y, Liu Y, Cai ZW, Xu YY, Chen J, Yu WQ, Yang PY*, Lei QY*. (2016) Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nature Communications, 7:11960.

• Wu S., Wang D., Liu J., Feng Y., Weng J., Gao X., Liu J.*, Wang W.* (2017) “The Dynamic Multisite Interactions between Two Intrinsically Disordered Proteins”Angew. Chem. Int. Ed. Engl. 56:7515-7519.

• Ya-Kun Zhang, Yuan-Yuan Qu, Yan Lin, Xiao-Hui Wu, Hou-Zao Chen, Xu Wang, Kai-Qiang Zhou,Yun Wei, Fushen Guo, Cui-Fang Yao, Xia-Di He, Li-Xia Liu, Chen Yang, Zong-Yuan Guan,Shi-Dong Wang, Jianyuan Zhao, De-Pei Liu, Shi-Min Zhao,*& Wei Xu.* Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients. Nature Communications 2017 Sep 6 8:464

• Xia-Di He, Wei Gong, Jia-Nong Zhang, Ji Nie, Cui-Fang Yao, Fu-Shen Guo, Yan Lin, Xiao-Hui Wu, Feng Li, Jie Li, Wei-Cheng Sun, En-Duo Wang, Yan-Peng An, Hui-Ru Tang, Guo-Quan Yan,Yang PY, Yun Wei, Yun-Zi Mao, Peng-Cheng Lin, Jian-Yuan Zhao, Yanhui Xu*, Wei Xu* & Shi-Min Zhao*. Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations. Cell Metabolism 2018 Jan 9 27,1-16

• Liu R, Lu Z, Gu J, Liu J, Huang E, Liu X, Wang L, Yang J, Deng Y, Qian J, Luo F, Wang Z, Zhang H, Jiang X, Zhang D, Qian J, Liu G, Zhu H, Qian Y, Liu Z, Chu Y*. MicroRNAs 15A and 16-1 Activate Signaling Pathways That Mediate Chemotaxis of Immune Regulatory B cells to Colorectal Tumors. Gastroenterology. 2017 Oct 11. pii: S0016-5085(17)36240-6. doi: 10.1053/j.gastro.2017.09.045. [Epub ahead of print]

• Lu Z, Liu J, Liu X, Huang E, Yang J, Qian J,3, Zhang D, Liu R*, Chu Y*. MiR-15a/16-1 Suppresses AHR-dependent IL-22 Secretion in CD4+ T cells and Contributes to Immune-mediated Organ Injury. Hepatology. 2017 Oct 10. doi: 10.1002/hep.29573. [Epub ahead of print]

• Zhu, K., Shan, Z., Chen, X., Cai, Y., Cui, L., Yao, W., Wang, Z., Shi, P., Tian, C., Lou, J., Xie, Y., and Wen, W.* “Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch” EMBO Rep. (2017) 18, 1618-1630.

• Zhou Y, Do DC, Ishmael FT, Squadrito ML, Tang HM, Tang HL, Hsu MH, Qiu L, Li C, Zhang Y, Becker KG, Wan M, Huang SK, Gao P*. Mannose receptor modulates macrophage polarization and allergic inflammation through miR-511-3p. J Allergy Clin Immunol 2017. PMID: 28629744, pii: S0091-6749(17)30990-9. doi: 10.1016/j.jaci.2017.04.049. [Epub ahead of print]

• Liu Y, Zhang Y, Wang S, Dong Q., Shen Z, Wang W, Tao S, Gu C, Liu J, Xie Y, Qin L . Prospero-related homeobox 1 drives angiogenesis of hepatocellular carcinoma through selectively activating IL-8 expression. Hepatology 2017; 66(6):1894-1909 
  

• Shen Z, Yang H, Yang S, Wang W, Cui X, Zhou X, Liu W, Pan S, Liu Y, Zhang J, Zhang J, Xie Y, Liu J. Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of viral clearance. Nat Commun 2017; 8(1): 2119.

• Dang T, Duan WY, Yu B, Tong DL, Cheng C, Zhang YF, Wu W, Ye K, Zhang WX, Wu M, Wu BB, An Y, Qiu ZL, Wu BL. Autism-associated Dyrk1a truncation mutants impair neuronal dendritic and spine growth and interfere with postnatal cortical development. Mol Psychiatry. 2017 Feb 7. doi: 10.1038/mp.2016.253. PMID: 28167836

• Dang T, Duan WY, Yu B, Tong DL, Cheng C, Zhang YF, Wu W, Ye K, Zhang WX, Wu M, Wu BB, An Y, Qiu ZL, Wu BL. Autism-associated Dyrk1a truncation mutants impair neuronal dendritic and spine growth and interfere with postnatal cortical development. Mol Psychiatry. 2017 Feb 7. doi: 10.1038/mp.2016.253. PMID: 28167836

• Xingjun Zhu,  Qianqian Su,  Wei Feng*, Fuyou Li*, Anti-Stokes shift luminescent materials for bio-applications, Chem. Soc. Rev., 2017, 46(4), 1025-1039.

• Qianqian Su, Wei Feng, Dongpeng Yang, Fuyou Li*, Resonance Energy Transfer in Upconversion Nanoplatforms for Selective Biodetection, Acc. Chem. Res., 2017, 50(1), 32-40.

• Wang D^#, Wang F^#, Shi KH^#, Tao H, Li Y, Zhao R, Lu H, Duan WY, Qiao, B, Zhao SM*, Wang HY*, Zhao JY*. The Circulating Folate Decrease Induced by a Fidgetin Intronic Variant Is Associated with Reduced Congenital Heart Disease Susceptibility. CIRCULATION  2017May 2;,135(18):1733-1748

• Zhou X, Wang H. ACOX2 deficiency in primary malignant cardiac tumors.PNAS. 2017 May 2; 114(18):E3590-E3591

• Qiu YL, Gong JY, Feng JY, Wang RX, Han J, Liu T, Lu Y, Li LT, Zhang MH, Sheps JA, Wang NL, Yan YY, Li JQ, Chen L, Borchers CH, Sipos B, Knisely AS, Ling V, Xing QH, Wang JS. Defects in MYO5B are associated with a spectrum of previously undiagnosed low γ-glutamyltransferase cholestasis.Hepatology. 2017;65(5):1655-1669.

• Hou, G*., Chen, L*., Liu, G*., Li, L., Yang, Y., Yan, H., Zhang, H., Tang, J., Yang, Y., Lin, X., Chen, X., Luo, G., Zhu, Y., Tang, S., Zhang, J., Liu, H., Gu, Q., Zhao, L., Li, Y., Liu, L*., Zhou, W*., Wang, H*.Aldehyde dehydrogenase-2 (ALDH2) opposes hepatocellular carcinoma progression by regulating AMP-activated protein kinase signaling in mice.Hepatology.2017,65(5):1628-1644.

• Ran Lin*,YanMo,HaihongZha,ZhipengQu,PanchengXie,ZhengJiangZhu,YingXu,YueXiong*,Kun-LiangGuan*.（2017）Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis. Molecular cell, 68(1), 198-209.

• Zhen Wang, Peng Liu, Xin Zhou,Tianxiang Wang, Xu Feng, Yi-Ping Sun,Yue Xiong, Hai-Xin Yuan, and Kun-Liang Guan*(2017). Endothelin promotes colorectal tumorigenesis by activating YAP/TAZ. Cancer Research, 77(9), 2413-2423. 

• Yin, X., Liu, M., Tian, Y., Wang, J., & Xu, Y. * (2017). Cryo-EM structure of human DNA-PK holoenzyme. Cell Research, 27(11), 1341.  

• Rao, Q., Liu, M., Tian, Y., Wu, Z., Hao, Y., Song, L., Qin, Z.,Ding, C.,Wang, H.,Wang, J. *& Xu, Y. *(2017). Cryo-EM structure of human ATR-ATRIP complex. Cell research.

• Hui Fan, Pin Lv, Xiangru Huo, Jicheng Wu, Qianfeng Wang, Lu Cheng, Yun Liu, Qiqun Tang, Ling Zhang, Feng Zhang, Xiaoqi Zheng, Hao Wu and Bo Wen*(2017). The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes. Genome research, gr-224576.

• Feng R, Sang Q, Kuang Y, Sun X, Yan Z, Zhang S, Shi J, Tian G, Luchniak A, Fukuda Y, Li B, Yu M, Chen J, Xu Y, Guo L, Qu R, Wang X, Sun Z, Liu M, Shi H, Wang H, Feng Y, Shao R, Chai R, Li Q, Xing Q, Zhang R, Nogales E, Jin L, He L, Gupta ML Jr, Cowan NJ, Wang L. Mutations in TUBB8 and Human Oocyte Meiotic Arrest. N Engl J Med. 2016 Jan 21;374(3):223-32.

• Shen H, Xu W, Guo R, Rong B, Gu L, Wang Z, He C, Zheng L, Hu X, Hu Z, Shao ZM, Yang P, Wu F, Shi YG, Shi Y, Lan F. Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex. CELL. 2016 Apr 7;165(2):331-42.

• Ye QH, Zhu WW, Zhang JB, Qin Y, Lu M, Lin GL, Guo L, Zhang B, Lin ZH, Roessler S, Forgues M, Jia HL, Lu L, Zhang XF, Lian BF, Xie L, Dong QZ, Tang ZY, Wang XW, Qin LX. GOLM1 Modulates EGFR/RTK Cell-Surface Recycling to Drive Hepatocellular Carcinoma Metastasis. CANCER CELL. 2016 SEP 12;30(3):444-58.

• Yuan HX, Guan KL. Structural insights of mTOR complex 1. CELL RES. 2016 Mar;26(3):267-8.

• Wang YP, Wei Z, Jian W, Xian H, Yong Z, Wang TS, Xue G, Xu YY, Zou SW, Liu YB, Cheng JK, Lei QY. Arginine Methylation of MDH1 by CARM1 Inhibits Glutamine Metabolism and Suppresses Pancreatic Cancer. MOL CELL. 2016 Nov 17;64(4):673-687.

• Ye DX, Ma YY, Zhao W, Cao HM, Kong JL, Xiong HM, Möhwald H. ZnO-Based Nanoplatforms for Labeling and Treatment of Mouse Tumors without Detectable Toxic Side Effects. ACS NANO. 2016 Apr 26;10(4):4294-300.

• Wu D, Liu G, Liu Y, Saiyin H, Wang C, Wei Z, Zen W, Liu D, Chen Q, Zhao Z, Zou L, Huang H, Jiang S, Yu L. Zinc finger protein 191 inhibits hepatocellular carcinoma metastasis via discs large 1-mediated yes associated protein inactivation. HEPATOLOGY. 2016 Oct 1;64(4):1149-62.

• Yuan SX, Wang J, Yang F, Tao QF, Zhang J, Wang LL, Yang Y, Liu H, Wang ZG, Xu QG, Fang J, Liu L, Sun SH, Zhou WP. Long noncoding RNA DANCR increases stemness features of hepatocellular carcinoma by derepression of CTNNB1. HEPATOLOGY. 2016 Feb;63(2):499-511.

• Feng Y, Zhang L, Wu S, Liu Z, Gao X, Zhang X, Liu M, Liu J, Huang X, Wang W. Conformational Dynamics of apo-GlnBP Revealed by Experimental and Computational Analysis. Angewandte Chemie. 2016 Nov 2;55(45):13990-13994.

• Zhu X, Feng W, Chang J, Tan YW, Li J, Chen M, Sun Y, Li FY. Temperature-feedback upconversion nanocomposite for accurate photothermal therapy at facile temperature. NAT COMMUN. 2016 Feb 4;7:10437.

• Gao X, Lin SH, Ren F, Li JT, Chen JJ, Yao CB, Yang HB, Jiang SX, Yan GQ, Wang D, Wang Y, Liu Y, Cai Z, Xu YY, Chen J, Yu W, Yang PY, Lei QY. Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. NAT COMMUN. 2016 Jun 30;7:11960.

• Fang J, Cheng JD, Wang JL, Zhang Q, Liu MG, Gong R, Wang P, Zhang XD, Feng YY, Lan WX, Gong Z, Tang C, Wong JM, Yang HR, Cao CY, Xu YH. Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition. NAT COMMUN. 2016 Apr 4;7:11197.

• Zheng Q, Bao C, Guo W, Li S, Jie C, Bing C, Luo Y, Lyu D, Yan L, Shi GH, Liang LH, Gu JR, He XH. Huang SL. Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs. NAT COMMUN. 2016 Apr 6;7:11215.

• Xu Y, Shi Y, Fu J, Yu M, Feng R, Sang Q, Liang B, Chen B, Qu R, Li B, Yang Z, Mao XY, Kuang YP, Jin L, He L, Sun XX, Wang L. Mutations in PADI6 Cause Female Infertility Characterized by Early Embryonic Arrest. AM J HUM GENET. 2016 Sep 1;99(3):744-52.

• Guo X, Wang L, Li J ,Ding Z ,Xiao J ,Yin X ,He S ,Shi P ,Dong L, Li G ,Tian C ,Wang J ,Cong Y ,Xu Y. Structural insight into autoinhibition and histone H3-induced activation of DNMT3A. Nature. Jan 29 2015;517(7536):640-644.

• Hu L, Lu J, Cheng J, Rao Q, Li Z, Hou H, Lou Z, Zhang L, Li W, Gong W, Liu M, Sun C, Yin X, Li J, Tan X, Wang P, Wang Y, ,Fang D, Cui Q, Yang P, He C, Jiang H, Luo C, Xu Y. Structural insight into substrate preference for TET-mediated oxidation. Nature. Nov 5 2015;527(7576):118-122.

• Yu FX*, Zhao B, Guan KL*. Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer. Cell. 2015 Nov 5;163(4):811-28.

• Sun Y, Feng W, Yang P, Huang C, Li F. The biosafety of lanthanide upconversion nanomaterials. Chemical Society reviews. Mar 21 2015;44(6):1509-1525.

• Zhang Y, Zhang C, Jiang H, Yang P, Lu H. Fishing the PTM proteome with chemical approaches using functional solid phases. Chemical Society reviews. Nov 21 2015;44(22):8260-8287.

• Qiu Z, Guo W, Wang Q, Chen Z ,Huang S, Zhao F, Yao M, Zhao Y, He X. Yuan HX, Guan KL. The SIN1-PH Domain Connects mTORC2 to PI3K. Cancer discovery. Nov 2015;5(11):1127-1129.

• Chen M ,Guo Q ,Wang Y ,Zou Y, Wang G ,Zhang X ,Xu X ,Zhao M ,Hu F ,Qu D, Chen M, Wang M. Shifts in the Antibiotic Susceptibility, Serogroups, and Clonal Complexes of Neisseria meningitidis in Shanghai, China: A Time Trend Analysis of the Pre-Quinolone and Quinolone Eras. PLoS medicine. Jun 2015;12(6):e1001838; discussion e1001838.

• Wang Y, Xiao M, Chen X, Chen L, Xu Y, Lv L, Wang P, Yang H, Ma S, Lin H, Jiao B, Ren R, Ye D, Guan KL, Xiong Y . WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation. Molecular cell. Feb 19 2015;57(4):662-673.

• Yang Y1, Yin X1, Yang H1, Xu Y. Histone demethylase LSD2 acts as an E3 ubiquitin ligase and inhibits cancer cell growth through promoting proteasomal degradation of OGT. Molecular cell. Apr 2 2015;58(1):47-59.

• Zha Z, Han X, Smith MD, Liu Y, Giguère PM, Kopanja D, Raychaudhuri P, Siderovski DP, Guan KL, Lei QY, Xiong Y. A Non-Canonical Function of Gbeta as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation. Molecular cell. Jun 4 2015;58(5):794-803.

• Li F, He X, Ye D, Lin Y, Yu H, Yao C, Huang L, Zhang J, Wang F, Xu S, Wu X, Liu L, Yang C, Shi J, He X, Liu J, Qu Y, Guo F, Zhao J, Xu W, Zhao S. NADP+-IDH Mutations Promote Hypersuccinylation that Impairs Mitochondria Respiration and Induces Apoptosis Resistance. Molecular cell.Nov 19 2015; 60(4):661-75.

• Zhou X, Wang S, Wang Z, Feng X, Liu P, Lv XB, Li F, Yu FX, Sun Y, Yuan H, Zhu H, Xiong Y, Lei QY, Guan KL. Estrogen regulates Hippo signaling via GPER in breast cancer. The Journal of clinical investigation. May 2015;125(5):2123-2135.

• Li Y, Zheng Q, Bao C, Li S, Guo W, Zhao J, Chen D, Gu J, He X, Huang S. Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis.Cell research. Aug 2015;25(8):981-984.

• Gong R, Hong AW, Plouffe SW, Zhao B, Liu G, Yu FX, Xu Y, Guan KL .Opposing roles of conventional and novel PKC isoforms in Hippo-YAP pathway regulation. Cell research. Aug 2015;25(8):985-988.

• Wang Z, Wan Y, Qiu C, Quiñones-Parra S, Zhu Z, Loh L, Tian D, Ren Y, Hu Y, Zhang X, Thomas PG, Inouye M5 Doherty PC, Kedzierska K ,Xu J. Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8(+) T cells. Nature communications. 2015;6:6833.

• Cheng J ,Yang H ,Fang J ,Ma L ,Gong R, Wang P, Li Z, Xu Y. Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation. Nature communications. 2015;6:7023.

• Jia M, Shan Z, Yang Y, Liu C, Li J, Luo ZG, Zhang M, Cai Y, Wen W, Wang W. The structural basis of Miranda-mediated Staufen localization duringDrosophila neuroblast asymmetric division. Nature communications. 2015;6:8381.

• Yang HB, Xu YY, Zhao XN, Zou SW, Zhang Y, Zhang M, Li JT, Ren F, Wang LY, Lei QY. Acetylation of MAT IIalpha represses tumour cell growth and is decreased in human hepatocellular cancer. Nature communications. 2015;6:6973.

• Cai JB ,Shi GM ,Dong ZR ,Ke AW ,Ma HH ,Gao Q ,Shen ZZ ,Huang XY ,Chen H ,Yu DD ,Liu LX,Zhang PF ,Zhang C ,Hu MY ,Yang LX ,Shi YH ,Wang XY ,Ding ZB ,Qiu SJ ,Sun HC ,Zhou J ,Shi YG ,Fan J Ubiquitin-specific protease 7 accelerates p14(ARF) degradation by deubiquitinating thyroid hormone receptor-interacting protein 12 and promotes hepatocellular carcinoma progression. Hepatology.May 2015;61(5):1603-1614.

• Wang ZC, Gao Q, Shi JY, Guo WJ, Yang LX, Liu XY, Liu LZ, Ma LJ, Duan M, Zhao YJ, Wu YN, Gao DM, Wang XY, Shi GM, Ding ZB, Ke AW, Tang QQ, Cao Y, Zhou J, Fan J. Protein tyrosine phosphatase receptor S acts as a metastatic suppressor in hepatocellular carcinoma by control of epithermal growth factor receptor-induced epithelial-mesenchymal transition. Hepatology. 2015 Oct;62(4):1201-1214.

• Guo W, Qiu Z, Wang Z, Wang Q, Tan N, Chen T, Chen Z, Huang S, Gu J, Li J, Yao M, Zhao Y, He X. MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer. Hepatology. Oct 2015;62(4):1132-1144.

• Yuan HX, Wang Z, Yu FX, Li F, Russell RC, Jewell JL, Guan KL .NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition. Genes Dev. Nov 15 2015;29(22):2362-2376.

• Zhang B, Wang L, Zeng L, Zhang C, Ma H. Arabidopsis TOE proteins convey a photoperiodic signal to antagonize CONSTANS and regulate flowering time. Genes Dev. May 1 2015;29(9):975-987.

• Hui Yang, Lisha Zhou, Qian Shi, Yuzheng Zhao, Huaipeng Lin, Mengli Zhang, Shimin Zhao, Yi Yang, Zhi‐Qiang Ling, Kun‐Liang Guan, Yue Xiong, Dan Ye. SIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growth. The EMBO journal. Apr 15 2015;34(8):1110-1125.

• Wang YP, Zhou LS, Zhao YZ, Wang SW, Chen LL, Liu LX, Ling ZQ, Hu FJ, Sun YP, Zhang JY, Yang C, Yang Y, Xiong Y, Guan KL, Ye D. Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress. Embo Journal, 2014. 33(12):1304-1320.

• Jiang JH, Liu YF, Ke AW, Gu FM, Yu Y, Dai Z, Gao Q, Shi GM, Liao BY, Xie YH, Fan J, Huang XW, Zhou J. Clinical Significance of the Ubiquitin Ligase UBE3C in Hepatocellular Carcinoma Revealed by Exome Sequencing. Hepatology, 2014. 59(6):2216-2227.

• Yang, X.;Zhang, X. F.;Lu, X.;Jia, H. L.;Liang, L.;Dong, Q. Z.;Ye, Q. H., and Qin, L. X., MicroRNA-26a Suppresses Angiogenesis in Human Hepatocellular Carcinoma by Targeting Hepatocyte Growth Factor-cMet Pathway. Hepatology, 2014. 59(5): p. 1874-1885.

• Zhu TT, Roundtree IA, Wang P, Wang X, Wang L, Sun C, Tian Y, Li J, He C, Xu YH. Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine. Cell Research, 2014. 24(12): 1493-1496.

• Yang, H.;Lin, H. P.;Xu, H. Y.;Zhang, L.;Cheng, L.;Wen, B.;Shou, J. Y.;Guan, K. L.;Xiong, Y., and Ye, D., TET-catalyzed 5-methylcytosine hydroxylation is dynamically regulated by metabolites. Cell Research, 2014. 24(8): p. 1017-1020.

• Yan, X.;Fan, Y.;Wei, W.;Wang, P. P.;Liu, Q. F.;Wei, Y. J.;Zhang, L.;Zhao, G. P.;Yue, J. M., and Zhou, Z. H., Production of bioactive ginsenoside compound K in metabolically engineered yeast. Cell Research, 2014. 24(6): p. 770-773.

• Zhao, D.;Mo, Y.;Li, M. T.;Zou, S. W.;Cheng, Z. L.;Sun, V. P.;Xiong, Y.;Guan, K. L., and Lei, Q. Y., NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells. Journal of Clinical Investigation, 2014. 124(12): p. 5453-5465.

• Guo, R.;Zheng, L. J.;Park, J. W.;Lv, R. T.;Chen, H.;Jiao, F. F.;Xu, W. Q.;Mu, S. R.;Wen, H.;Qiu, J. S.;Wang, Z. T.;Yang, P. Y.;Wu, F. Z.;Hui, J. Y.;Fu, X. D.;Shi, X. B.;Shi, Y. G.;Xing, Y.;Lan, F., and Shi, Y., BS69/ZMYND11 Reads and Connects Histone H3.3 Lysine 36 Trimethylation-Decorated Chromatin to Regulated Pre-mRNA Processing. Molecular Cell, 2014. 56(2): p. 298-310.

• Li, R. C.;Liu, L. D.;Mo, Z. J.;Wang, X. Y.;Xia, J. L.;Liang, Z. L.;Zhang, Y.;Li, Y. P.;Mao, Q. Y.;Wang, J. J.;Jiang, L.;Dong, C. H.;Che, Y. C.;Huang, T.;Jiang, Z. W.;Xie, Z. P.;Wang, L. C.;Liao, Y.;Liang, Y.;Nong, Y.;Liu, J. S.;Zhao, H. L.;Na, R. X.;Guo, L.;Pu, J.;Yang, E. X.;Sun, L.;Cui, P. F.;Shi, H. J.;Wang, J. Z., and Li, Q. H., An Inactivated Enterovirus 71 Vaccine in Healthy Children. New England Journal of Medicine, 2014. 370(9): p. 829-837.

• Wu C, Zhang D, Kan M, et al. The draft genome of the large yellow croaker reveals well-developed innate immunity[J]. Nature Communications, 2014, 5(5):5227.

• Qiang Gao, Ying–Jun Zhao, Xiao–Ying Wang,Wei–Jie Guo,Song Gao,Lin Wei,Jie–Yi Shi, Guo–Ming Shi,Zhi–Chao Wang,Yuan–Nv Zhang,Ying–Hong Shi,Jie Ding,Zhen–Bin DingAi–Wu Ke,Zhi Dai,Fei–Zhen Wu,Hui Wang,Zhao–Ping Qiu,Zhi–Ao Chen,Zhen–Feng Zhang,Shuang–Jian Qiu,Jian Zhou,Xiang–Huo He,Jia Fan Activating Mutations in PTPN3 Promote Cholangiocarcinoma Cell Proliferation and Migration and Are Associated With Tumor Recurrence in Patients GASTROENTEROLOGY 146 (5)1397-1407

• Jian-Yuan Zhao, Bin Qiao, Wen-Yuan Duan, Xiao-Hong Gong, Qian-QianPeng, Song-Shan Jiang, Chen-Qi Lu, Yi-Jiang Chen, Hong-Bing Shen, Guo-Ying Huang, Li Jin, and Hong-Yan Wang. Genetic variants reducing MTR gene expression increase the risk of congenital heart disease in Han Chinese populations. Eur Heart J. 2014 Mar;35(11):733-42.

• Maolan Li, Zhou Zhang, Xiaoguang Li, Junyi Ye, Xiangsong Wu, Zhujun Tan, Chang Liu, Baiyong Shen, Xu-An Wang, Wenguang Wu, Daizhan Zhou, Di Zhang, Ting Wang, Bingya Liu, Kai Qu, Qichen Ding, Hao Weng, Qian Ding, Jiasheng Mu, Yijun Shu, Runfa Bao, Yang Cao, Peizhan Chen, Tianyu Liu, Lin Jiang, Yunping Hu, Ping Dong, Jun Gu, Wei Lu, Weibin Shi, Jianhua Lu, Wei Gong, Zhaohui Tang, Yong Zhang, Xuefeng Wang, Y Eugene Chin, Xiaoling Weng, Hong Zhang, Wei Tang, Yonglan Zheng, Lin He, Hui Wang, Yun Liu, Yingbin Liu. Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway. NATURE GENETICS, 46(8):872-876

• Liu, Yi; Chen, Min; Cao, Tianye; Sun, Yun; Li, Chunyan; Liu, Qian; Yang, Tianshe; Yao, Liming; Feng, Wei; Li, Fuyou. A Cyanine-Modified Nanosystem for in Vivo Upconversion Luminescence Bioimaging of Methylmercury. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2013;135(26):9869-9876.

• Liu Qian, Yin Baoru, Yang Tianshe, Yang Yongchao, Shen Zhen, Yao Ping, Li Fuyou. A General Strategy for Biocompatible, High-Effective Upconversion Nanocapsules Based on Triplet-Triplet Annihilation. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013;135(13):5029-503710.677

• Lin, Ruiting; Tao, Ren; Gao, Xue; Li, Tingting; Zhou, Xin; Guan, Kun-Liang; Xiong, Yue; Lei, Qun-Ying. Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth.MOLECULAR CELL 2013;51(4):506-518.

• Wang, Yi; Lu, James; Yu, Jin; Gibbs, Richard A.; Yu, Fuli. An integrative variant analysis pipeline for accurate genotype/haplotype inference in population NGS data. GENOME RESEARCH 2013;23(5):833-842.

• Zhang, Zheng-Yong; Xu, Yu-Dong; Ma, Ying-Ying; Qiu, Li-Li; Wang, Yi; Kong, Ji-Lie; Xiong, Huan-Ming. Biodegradable ZnO@polymer CoreShell Nanocarriers: pH-Triggered Release of Doxorubicin In Vitro.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2013;52(15):4127-4131.

• Yun Sun, Xingjun Zhu, Juanjuan Peng, and Fuyou Li. Core Shell Lanthanide Upconversion Nanophosphors as Four-Modal Probes for Tumor Angiogenesis Imaging. ACS NANO, 2013;7(12):11290-11300.

• Hu L, Li Z, Cheng J, Rao Q, Gong W, Liu M, Shi YG, Zhu J, Wang P, Xu Y. Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation. Cell.2013;155(7):1545-1555.

• Zhang Xueyang, Zhu Shaochun, Xiong Ya, Deng Chunhui, Zhang Xiangmin. Development of a MALDI-TOF MS Strategy for the High-Throughput Analysis of Biomarkers: On-Target Aptamer Immobilization and Laser-Accelerated Proteolysis. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013;52(23):6055-6058.

• Zhao Di, Zou Shao-Wu, Liu Ying, Zhou Xin, Mo Yan, Wang Ping, Xu Yan-Hui, Dong Bo, Xiong Yue, Lei Qun-Ying, Guan Kun-Liang. Lysine-5 Acetylation Negatively Regulates Lactate Dehydrogenase A and Is Decreased in Pancreatic Cancer. CANCER CELL, 2013;23(4):464-476.

• Yang X, Liang L, Zhang XF, Jia HL, Qin Y, Zhu XC, Gao XM, Qiao P, Zheng Y, Sheng YY, Wei JW, Zhou HJ, Ren N, Ye QH, Dong QZ, Qin LX. MicroRNA-26a Suppresses Tumor Growth and Metastasis of Human Hepatocellular Carcinoma by Targeting IL-6-Stat3 Pathway. HEPATOLOGY, 2013;58(1):158-70.

• Lv, L., Xu, Y-P., Zhao, D., Li, F-L., Wang, W., Sasaki N., Jiang, Y., Zhou, X., Li, T-T., Guan, K-L.,Lei, Q-Y.,and Xiong, Y. Mitogenic and oncogenic stimulation of K433 acetylation promote PKM2 protein kinase activity and nuclear localization. MOLECULAR CELL 2013;52(4):340-352.

• Dong Qiong-Zhu, Zhang Xiao-Fei, Zhao Yue, Jia Hu-Liang, Zhou Hai-Jun, Dai Chun, Sun Hai-Jing, Qin,Yi, Zhang Wei-De, Ren Ning, Ye Qing-Hai, Qin Lun-Xiu. Osteopontin promoter polymorphisms at locus -443 significantly affect the metastasis and prognosis of human hepatocellular carcinoma. HEPATOLOGY, 2013;57(3):1024-1034.

• Liu, Yanfeng; Zhang, Ju-Bo; Qin, Yi; Wang, Wei; Wei, Lili; Teng, Yigang; Guo, Lei; Zhang, Bo; Lin, Zhenhai; Liu, Jing; Ren, Zheng-Gang; Ye, Qing-Hai; Xie, Youhua. PROX1 promotes hepatocellular carcinoma metastasis by way of up-regulating hypoxia-inducible factor 1 expression and protein stability. HEPATOLOGY 2013;58(2):692-705.

• Jiang, Zhen; Xu，Ming; Li,Fuyou; Yu Yanlei. Red-Light-Controllable Liquid-Crystal Soft Actuators via Low-Power Excited Upconversion Based on Triplet−Triplet Annihilation. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2013, 135(44), 16446-16453.

• Jia, Xu; Zhang, Jing; Sun, Wenxia; He, Weizhi; Jiang, Hengyi; Chen, Dongrong; Murchie, Alastair I. H. Riboswitch Control of Aminoglycoside Antibiotic Resistance. CELL 2013;152(1-2):68-81.

• Fang R, Chen F, Dong Z, Hu D, Barbera AJ, Clark EA, Fang J, Yang Y, Mei P, Rutenberg M, Li Z, Zhang Y, Xu Y, Yang H, Wang P, Simon MD, Zhou Q, Li J, Marynick MP, Li X, Lu H, Kaiser UB, Kingston RE, Xu Y, Shi YG. LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation. Mol Cell. 2013 Feb 7;49(3):558-70.

• Zhang, T.F.; Wang, S.W.; Lin, Y.; Xu, W.; Ye, D.; Xiong, Y.; Zhao, S.M.; Guan, K.L.. Acetylation Negatively Regulates Glycogen Phosphorylase by Recruiting Protein Phosphatase 1. CELL METABOLISM 2012;15(1):75-87.

• Lu, P.L.; Han, X.W.; Qi, J.; Yang, J.G.; Wijeratne, Asela J.; Li, T.; Ma, H. Analysis of Arabidopsis genome-wide variations before and after meiosis and meiotic recombination by resequencing Landsberg erecta and all four products of a single meiosis. GENOME RESEARCH, 2012;22(3):508-518.

• Liu, Q.; Yang, T.S.; Feng, W.; Li, F.Y. Blue-Emissive Upconversion Nanoparticles for Low-Power-Excited Bioimaging in Vivo. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012;134(11):5390-5397.

• Mengtao Xiao, Hui Yang, Wei Xu, Shenghong Ma, Huaipeng Lin, Honguang Zhu, Lixia Liu, Ying Liu, Chen Yang, Yanhui Xu, Shimin Zhao, Dan Ye, Yue Xiong and Kun-Liang Guan. Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors. Genes Dev. 2012 Jun 15; 26(12): 1326–1338.

• Yu KD, Shao ZM. Initiation, evolution, phenotype and outcome of BRCA1 and BRCA2 mutation-associated breast cancer. NATURE REVIEWS CANCER. 2012;12(5):372-U67.

• Jia, X.; Zhang, J.; Sun, W.X.; He, W.Z.; Jiang, H.Y.; Chen, D.R.; Murchie,A.H.. Riboswitch Control of Aminoglycoside Antibiotic Resistance. CELL 2013;152:68–81.

• Shen, Q.J.; Fan, J.; Yang, X.R.; Tan, Y.X.; Zhao, W.F.; Xu, Y.; Wang, N.; Niu, Y.D.; Wu, Z.; Zhou, J.; Qiu, S.J.; Shi, Y.H.; Yu, B.; Tang, N.; Chu, W.; Wang, M.; Wu, J.H.; Zhang, Z.G.; Yang, H.L.; Gu, J.R.; Wang, H.Y.; Qin, W.X.. Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study. LANCET ONCOLOGY 2012;13(8):817-826.

• Ma, W.F.; Zhang, Y.; Li, L.L.; You, L.J.; Zhang, P.; Zhang, Y.T.; Li, J.M.; Yu, M.; Guo, J.; Lu, H.J.; Wang, C.C.. Tailor-Made Magnetic Fe(3)O(4)@mTiO(2) Microspheres with a Tunable Mesoporous Anatase Shell for Highly Selective and Effective Enrichment of Phosphopeptides. ACS NANO 2012;6(4):3179-3188.

• Ye, D.; Xiong, Y.; Guan, K.L.. The mechanisms of IDH mutations in tumorigenesis. CELL RESEARCH 2012;22(7): 1102-1104.

• Liu Q, Sun Y, Li CG, Zhou J, Li CY, Yang TS, Zhang XZ, Yi T, Wu DM, Li FY. 18F-Labeled Magnetic-Upconversion Nanophosphors via Rare-Earth Cation-Assisted Ligand Assembly. ACS NANO, 2011;5(4):3146-3157.

• Jiang W, Wang S, Xiao M, Lin Y, Zhou L, Lei Q, Xiong Y, Guan KL, Zhao S. Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase. Mol Cell. 2011 Jul 8;43(1):33-44.

• Li C, Yu M, Sun Y, Wu Y, Huang C, Li F. A nonemissive iridium(III) complex that specifically lights-up the nuclei of living cells. J Am Chem Soc. 2011 Jul 27;133(29):11231-9.

• Lv L, Li D, Zhao D, Lin R, Chu Y, Zhang H, Zha Z, Liu Y, Li Z, Xu Y, Wang G, Huang Y, Xiong Y, Guan KL, Lei QY. Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth. Mol Cell. 2011 Jun 24;42(6):719-30.

• Ke, A.W.; Shi, G.M.; Zhou, J.; Huang, X.Y.; Shi, Y.H.; Ding, Z.B.; Wang, X.Y.; Devbhandari, RP; Fan, J. CD151 Amplifies Signaling by Integrin alpha 6 beta 1 to PI3K and Induces the Epithelial-Mesenchymal Transition in HCC Cells. GASTROENTEROLOGY.2011;140(5):1629-U389. 12.821

• Su ZX. Huang W. Gu X. Comment on Positive Selection of Tyrosine Loss in Metazoan Evolution. SCIENCE, 2011;332(6032):915-916.

• Yu KD, Shao ZM. ESR1 gene amplification: another mechanism regulating the cellular levels of ER alpha. NATURE REVIEWS CANCER, 2011;11(11):823-824.

• Hu L, Li Z, Wang P, Lin Y, Xu Y. Crystal structure of PHD domain of UHRF1 and insights into recognition of unmodified histone H3 arginine residue 2. Cell Res. 2011 Sep;21(9):1374-8

• Chen ZJ, Zhao H, He L, Shi Y, Qin Y, Shi Y, Li Z, You L, Zhao J, Liu J, Liang X, Zhao X, Zhao J, Sun Y, Zhang B, Jiang H, Zhao D, Bian Y, Gao X, Geng L, Li Y, Zhu D, Sun X, Xu JE, Hao C, Ren CE, Zhang Y, Chen S, Zhang W, Yang A, Yan J, Li Y, Ma J, Zhao Y. Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3. Nat Genet. 2011 Jan;43(1):55-9.

• Gong R. Li L. Liu Y. Wang P. Yang HR. Wang L. Cheng JD. Guan KL. Xu YH. Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation. GENES & DEVELOPMENT, 2011;25(16):1668-1673.

• Thomas Nicholson; Chen,T.P.; Xu,G.L.; Shi,Y.; Zhang,K.; Shi,Y.J. Genome-wide Regulation of 5hmC, 5mC,and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells. MOLECULAR CELL, 2011;42(4):451-464.

• Zhu,J.W.;Wen,W.Y.;Zheng,Z.;Shang,Y.;Wei,Z.Y.;Xiao,Z.N.;Pan,Z.;Du,Q.S.;Wang,W.N.;Zhang,M.J.. LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and G alpha i/LGN/NuMA Pathways. MOLECULAR CELL2011;43(3):418-431.

• Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim SH, Ito S, Yang C, Wang P, Xiao MT, Liu LX, Jiang WQ, Liu J, Zhang JY, Wang B, Frye S, Zhang Y, Xu YH, Lei QY, Guan KL, Zhao SM, Xiong Y. Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of alpha-Ketoglutarate-Dependent Dioxygenases. Cancer Cell. 2011 Jan 18;19(1):17-30.

• Rajakumara E, Wang Z, Ma H, Hu L, Chen H, Lin Y, Guo R, Wu F, Li H, Lan F, Shi YG, Xu Y, Patel DJ, Shi Y. PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression. Mol Cell. 2011 Jul 22;43(2):275-84.

• Zou Y, Huang W, Gu Z, Gu X. Predominant Gain of Promoter TATA Box after Gene Duplication Associated with Stress Responses. MOLECULAR BIOLOGY AND EVOLUTION, 2011;28(10):2893-2904.

• Liu W, Wen W, Wei Z, Yu J, Ye F, Liu CH, Hardie RC, Zhang M. The INAD Scaffold Is a Dynamic, Redox-Regulated Modulator of Signaling in the Drosophila Eye. CELL, 2011;145(7):1088-1101.

• Yu KD, Shao ZM. The two faces of autophagy and the pathological underestimation of DCIS. Nat Rev Cancer. 2011 Jul 22;11(8):618.

• Zhao, S.m.; Xu, W.; Jiang, W.Q.; Yu, W.; Lin, Y.; Zhang, T.F.; Yao, J.; Zhou, L.; Zeng, Y.X.; Li, H.; Li, Y.X.; Shi, J.; An, W.L.; Susan M. Hancock; He, F.C.; Qin, L.X.; Chin, J.; Yang, P.Y.; Chen, X.; Lei, Q.Y.; Xiong, Y.; Guan, K.L. Regulation of Cellular Metabolism by Protein Lysine Acetylation. SCIENCE 2010;327(5968):1000-1004.

• Wang, Q., Zhang, Y., Yang, C., Xiong, H., Lin, Y., Yao, J., Li, H., Xie, L., Zhao, W., Yao, Y., Ning, Z.-B., Zeng, R., Xiong, Y., Guan, K.-L., Zhao, S., and Zhao, G.-P. (2010) Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux. SCIENCE327, 1004-1007

• Shi, G.M.; Ke, A.W.; Zhou, J.; Wang, X.Y.; Xu, Y.; Ding, Z.B.;Ranjan Prasad Devbhandari, Huang, X.Y.; Qiu, S.J.; Shi, Y.H.; Dai, Z.; Yang, X.R.; Yang, G.H.; Fan, J. CD151 Modulates Expression of Matrix Metalloproteinase 9 and Promotes Neoangiogenesis and Progression of Hepatocellular Carcinoma. HEPATOLOGY 2010;52(1):183-196

• Zhou, H.J.; Huang, H.; Shi, J.; Zhao, Y.; Dong, Q.Z.; Jia, H.L.; Liu, Y.K.; Ye, Q.H.; Sun, H.C.; Zhu, X.D.; Fu, L.Y.; Guo, K.; Gao, D.M.; Sun, J.; Yan, Z.W.; Ren, N.; Tang, Z.Y.; Qin, L.X. Prognostic value of interleukin 2 and interleukin 15 in peritumoral hepatic tissues for patients with hepatitis B-related hepatocellular carcinoma after curative resection. GUT 2010;59(12):1699-1708.

• Yang, Y.; Hu, L.L.; Wang, P.; Hou, H.F.; Lin, Y.; Liu, Y.; Li, Z.; Gong, R.; Feng, X.; Zhou, L.; Zhang, W.; Dong, Y.H.; Yang, H.R.; Lin, H.Q.; Wang, Y.Q.; Charlie D.Chen; Xu, Y.H.. Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans. Cell Research 2010;20:886-898.

• Li, Z.; Zhao, B.; Wang, P.; Chen, F.; Dong, Z.H.; Yang, H.R.; Guan, K.L.; Xu, Y.H.. Structural insights into the YAP and TEAD complex. GENES & DEVELOPMENT 2010;24:235–240.

• Chen, H.M.; Deng, C.H.; Zhang, X.M.. Synthesis of Fe3O4@SiO2@PMMA Core–Shell–Shell Magnetic Microspheres for Highly Efficient Enrichment of Peptides and Proteins for MALDI-ToF MS Analysis. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2010;49(3):607-611.

• Xue YH, Zhang XF, Dong QZ, Sun J, Dai C, Zhou HJ, Ren N, Jia HL, Ye QH, Qin LX. Thrombin is a Therapeutic Target for Metastatic Osteopontin-Positive Hepatocellular Carcinoma. Hepatology, 2010;52(6):2012-2022.

• Wang W, Weng J, Zhang X, Liu M, Zhang M. Creating Conformational Entropy by Increasing Interdomain Mobility in Ligand Binding Regulation:A Revisit to N-terminal Tandem PDZ Domains of PSD-95. Journal of the American Chemical Society, 2009; 131(2):787-796.

• Zhao, S., Lin, Y., Xu, W., Jiang, W., Zha, Z., Wang, P., Yu, W., Li, Z., Gong, L., Peng, Y., Ding, J., Lei, Q., Guan, K.-L., and Xiong, Y. (2009) Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1 alpha. Science 324, 261-265

• Ze Li, Bin Zhao, Ping Wang, Fei Chen, Zhenghong Dong, Huirong Yang, Kun-Liang Guan and Yanhui Xu. Structural insights into the YAP and TEAD complex. Genes & Development, 2010,24(3):235-240

• Ke AW, Shi GM, Zhou J, Wu FZ, Ding ZB, Hu MY, Xu Y, Song ZJ, Wang ZJ, Wu JC, Bai DS, Li JC, Liu KD, Fan J. Role of Overexpression of CD151 and/or c-Met in Predicting Prognosis of Hepatocellular Carcinoma. Hepatology. 2009 Feb;49(2):491-503.

• Huan-Ming Xiong, Xiao-Yan Guan, Ling-Hua Jin, Wen-Wen Shen, Hao-Jie Lu and Yong-Yao Xia. Surfactant-Free Synthesis of SnO2@PMMA and TiO2@PMMA Core-Shell Nanobeads Designed for Peptides/Proteins Enrichment and MALDI-TOF MS Analysis Angew. Angew Chem Int Ed Engl, 2008, 47, 4204-4207.

• Sun BS, Dong QZ, Ye QH, Sun HJ, Jia HL, Zhu XQ, Liu DY, Chen J, Xue Q, Zhou HJ, Ren N, Qin LX. Lentiviral-mediated miRNA against osteopontin suppresses tumor growth and metastasis of human hepatocellular carcinoma. Hepatology, 2008 48(6):1834-42.

• Shuhua Xu and Li Jin. A Genome-wide Analysis of Admixture in Uyghurs and a High-Density Admixture Map for Disease-Gene Discovery. Am J Hum Genet, 2008, 83, 322-336.

• YY Shi, G He, Z Zhang, W Tang, J Zhang Jr, Q Zhao, J Zhang Sr, XW Li, ZR Xi, C Fang, XZ Zhao, GY Feng and L He. A study of rare structural variants in schizophrenia patients and normal controls from Chinese Han population. Molecular Psychiatry, 2008; 13, 911-913.

• Deng G, Zhou G, Zhang R, Zhai Y, Zhao W, Yan Z, Deng C, Yuan X, Xu B, Dong X, Zhang X, Zhang X, Yao Z, Shen Y, Qiang B, Wang Y, He F. Regulatory polymorphisms in the promoter of CXCL10 gene and disease progression in male hepatitis B virus carriers. Gastroenterology, 2008 Mar;134(3):716-26.

• Zhao B, Lei QY (co-corresponding authors), Guan KL. The Hippo-YAP pathway: new connections between regulation of organ size and cancer. Current Opinion Cell Biology, 2008 Dec;20(6):638-46.

• Lu K, Yin X, Weng T, Xi S, Li L, Xing G, Cheng X, Yang X, Zhang L, He F. Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1. Nat Cell Biol, 2008, 10(8):994-1002.

• Shimin Zhao, Kunliang Guan. Substrate selectivity APPLies to Akt. Cell, 2008 May;133,399-400.

• Shuhua Xu,Wei Huang,Haifeng Wang,Yungang He,Ying Wang,Yi Wang,Ji Qian,Momiao Xiong,and Li Jin.Dissecting Linkage Disequilibrium in frican-American Genomes: Roles of Markers and Individuals.Mol. Biol. Evol. 2007, 24: 2049–2058.

• Jia WT, Chen XH, Lu HJ, Yang PY.CaCO3-poly(methyl methacrylate) nanoparticles for fast enrichment of low-abundance peptides followed by CaCO3-core removal for MALDI-TOF MS analysis.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 45 (20): 3345-3349 2006 

• Zhai Y, Zhou G, Deng G, Xie W, Dong X, Zhang X, Yu L, Yang H, Yuan X, Zhang H, Zhi L, Yao Z, Shen Y, Qiang B, He F. Estrogen receptor alpha polymorphisms associated with susceptibility to hepatocellular carcinoma in hepatitis B virus carriers. Gastroenterology. 2006 Jun;130(7):2001-9.