Haiwei Chen, Ph.D.

Education

• PhD    Peking University School of Life Sciences (2016)

• BA     Sun Yat-Sen University School of Life Sciences (2010)

Work experience

• Associate Professor         Fudan University Shanghai Medical College (2022)

• Associate Research Scientist     Yale University School of Medicine (2022)

• Postdoc Associate           Yale University School of Medicine (2018)

Contact

Institutes of Biomedical Sciences, Fudan University, Shanghai 200032

Email: chen_haiwei@fudan.edu.cn

Biography

Chen haiwei, PhD, is an associate professor of Institutes of Biomedical Sciences at Fudan University. Chen received his bachelor degree in Biology from Sun Yat-Sen University, his PhD in Cell Biology from Peking University, and completed his postdoctoral training at Yale University. Chen lab focuses on developing Next-Generation Sequencing (NGS) based functional high-throughput screening systems, dissecting human physiology (“How human body maintains homeostasis”) and human pathology (“how disease develops”).

Research Areas

• The long-term goal of the Chen lab is to systemically understand human biology and human pathology. To this end, we develop diverse bioactivity-based high-throughput screening systems, dissecting the regulatory networks of host signaling pathways, host-microbiome interactions, functional profiling of orphan GPCRs et al.

Research interest

Systems Biology; GPCR Biology; Host-Microbiome Interactions

Selected Publications

1. Chen H, Rosen CE, Gonzalez-Hernandez JA, Ring AM, Palm NW. Highly multiplexed bioactivity screening reveals human and microbiota metabolome-GPCRome interactions. Cell(under revision)

2. Chen H,NwePK,YangY,RosenCE,BieleckaAA,KuchrooM,ClineGW, Kruse AC, RingAM,CrawfordJM,PalmNW.Aforwardchemicalgeneticscreen reveals gut microbiota metabolitesthatmodulatehostphysiology.Cell. 2019 May 16; 177(5): 1217-1231. e18.

3. Chen H, Yang Y, Xu H, Yang W, Zhai Z, Chen DY. Ring finger protein 166 potentiates RNA virus-induced interferon- production via enhancing the ubiquitination of TRAF3 and TRAF6. Scientific Reports 5, 14770. PMID: 26456228.