Feng Zhou, Ph.D.

Education

• August 2002 – June 2007 University of Delaware, Newark, DE

Ph.D., Analytical Chemistry,

• June 2000 Fudan University, Shanghai, China Bachelor of Science, Analytical Chemistry,

Work experience

• Aug 2014 – Present  Principle Investigator,

Fudan University, Institutes of Biomedical Sceinces, Shanghai, China

• Aug 2007 – Aug 2014, Research Fellow, Advisor: Jarrod A. Marto

Harvard Medical School, Department of Biological Chemistry and Molecular Pharmacology, Boston, MA

• September 2002 – June 2007, Research assistant, Advisor: Murray V. Johnston, P

University of Delaware, Department of Chemistry and Biochemistry, Newark,DE

• January 2000 – June 2002, Research assistant, Advisor: Pengyuan Yang

Fudan University, Department of Chemistry, Shanghai, China

Contact

Institutes of Biomedical Sciences, Fudan University, Shanghai 200032 Tel: +86 302-388-0633

Emial: zf12345@yahoo.co

Research interest

• Development of Genome Scale Proteomics Platform (Identification more than 13,000 proteins from Embryonic Stem Cell)

• Study of Ultrasensitive Proteomic Platform (Characterization of proteins interacting with specific DNA loci.)

• Whole Proteome Quantification (Obtaining more than 13,000 proteins from single human cell line)

Selected Publications

1. Liu X, Zhang Y, Chen Y, Li M, Zhou F*, Li K, Cao H, Ni M, Liu Y, Gu Z, Dickerson KE, Xie S, Hon GC, Xuan Z, Zhang MQ, Shao Z, Xu J*. In Situ Capture of Chromatin Interactions by Biotinylated dCas9. Cell. 2017, 170(5): 1028-1043. IF: 36.410 (* Corresponding author）

2. Highlighted in Nature Reviews Genetics volume 18, page641(2017): CRISPR CAPTURE for multi-omic probing of genomic loci

3. Liu, Y., Y. Fu, Q. Wang, M. Li, Z. Zhou, D. Dabbagh, C. Fu, H. Zhang, S. Li, T. Zhang, J. Gong, X. Kong, W. Zhai, J. Su, J. Sun, Y. Zhang, X.-F. Yu, Z. Shao, F. Zhou*, Y. Wu* and X. Tan* Proteomic profiling of HIV-1 infection of human CD4+ T cells identifies PSGL-1 as an HIV restriction factor. Nature Microbiology. 4, no. 5 (2019/05/01 2019): 813-25. IF: 14.147 （* Corresponding author）

4. Highlighted in China Daily (2019): Protein found in human body could inhibit progress of HIV

5. Liu X, Zhang Y, Ni M, Cao H, Signer RAJ, Li D, Li M, Gu Z, Hu Z, Dickerson KE, Weinberg SE, Chandel NS, DeBerardinis RJ, Zhou F*, Shao Z*, Xu J*. Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation. Nature Cell Biology 2017; 19(6): 626-638.  IF: 20.032 （* Corresponding author）

6. Highlighted in Nature Cell Biology volume 19, pages589–591(2017): Mitochondria link metabolism and epigenetics in haematopoiesis

7. Highlighted in Science Signaling  27 Jun 2017:Vol. 10, Issue 485: New connections: mTORC1 matures red blood cells

8. Lin Z, Li S, Feng C, Yang S, Wang H, Ma D, Zhang J, Gou M, Bu D, Zhang T, Kong X, Wang X, Sarig O, Ren Y, Dai L, Liu H, Zhang J, Li F, Hu Y, Padalon-Brauch G, Vodo D, Zhou F, Chen T, Deng H, Sprecher E, Yang Y, Tan X. Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility. Nat Genet. 2016; 48(12): 1508-1516.  IF: 31.616

9. Norberg E, Lako A, Chen P-H, Stanley IA, Zhou F, Ficarro SB, Chapuy B, Chen L, Rodig S, Shin D. Differential contribution of the mitochondrial translation pathway to the survival of diffuse large B-cell lymphoma subsets. Cell Death & Differentiation. 2016.  IF: 8.218

10. Zhou F, Lu Y, Ficarro SB, Adelmant GO, Luckey CJ, Marto JA. Genome-scale proteome quantification by DEEP SEQ mass spectrometry. Nature Communications. DOI: 10.1038/ncomms3171. IF: 11.329

11. Zhou F, Lu Y, Ficarro SB, Webber JT, Marto JA. A nanoflow low pressure high peak capacity single dimension LC-MS/MS platform for high throughput in-depth analysis of mammalian proteomes. Analytical Chemistry. 2012: 84(11): 5133-5139. Times Cited: 4. IF: 5.695

12. Caro P, Kishan AU, Norberg, E, Stanley IA, Chapuy B, Ficarro SB, Polak K, Tondera D, Gounarides J, Yin H, Green MR, Zhou F, Chen LF, Monti S, Marto JA, Shipp MA, Danial NN. Metabolic Signatures Uncover Distinct Targets in Molecular Subsets of Diffuse Large B Cell Lymphoma. Cancer Cell 2012:22, 547-560. Times Cited: 10. IF: 24.755

13. Zhou F, Sikorski TW, Ficarro SB, Webber JT, Marto JA. Online nanoflow reversed phase-strong anion exchange-reversed phase liquid chromatography-tandem mass spectrometry platform for efficient and in-depth proteome sequence Analysis of Complex Organisms. Analytical Chemistry. 2011;83(18):6996-7005. Times Cited: 15. IF: 5.695

14. Zhou F, Cardoza JD, Ficarro SB, Adelmant GO, Lazaro JB, Marto JA. Online nanoflow RP-RP-MS reveals dynamics of multicomponent Ku complex in response to DNA damage. J Proteome Res. 2010;9(12):6242-55.Times Cited: 21. IF: 5.056

15. Zhou F, Hanson TE, Johnston MV. Intact protein profiling of C. tepidum by capillary isoelectric focusing, reversed phase liquid chromatography and mass spectrometry with pI determination. Analytical Chemistry 2007, 79: 7145-7156. Times Cited: 32. IF: 5.695

16. Zhou F, Johnston MV. Protein profiling by capillary isoelectric focusing, reversed phase liquid chromatography and mass spectrometry. Electrophoresis 2005, 26: 1383-1388. Times Cited: 33. IF: 3.261

17. Ginter JM, Zhou F, Johnston MV. Generating protein sequence tags by combining cone and conventional collision induced dissociation in a quadrupole time-of-flight mass spectrometer. Journal of the American Society for Mass Spectrometry 2004, 15: 1478-1486. Times Cited: 26. IF: 3.592

18. Zhou F, Johnston MV. Protein characterization by on-line capillary isoelectric focusing, reverse phase liquid chromatography and mass spectrometry. Analytical Chemistry 2004, 76: 2734 – 2740. Times Cited: 64. IF: 5.695

19. Zhou F, Shui WQ, Lu Y, Yang PY, Guo YL. High accuracy mass measurement of peptides with internal calibration using a dual electrospray ionization sprayer system for protein identification. Rapid Communications in Mass Spectrometry 2002, 16: 505-511. Times Cited: 22. IF: 2.509

20. Lu Y, Zhou F, Shui WQ, Bian LP, Yang PY.Pulsed electrospray for mass spectrometry. Analytical Chemistry 2001, 73: 4748-4753.  Times Cited: 17. IF: 5.695

21. Wei JF, Shui WQ, Zhou F, Lu Y, Chen KK, Xu GB, Yang PY. Naturally and externally pulsed electrospray. Mass Spectrometry Reviews 2002, 21: 148-162. Times Cited: 37. IF: 7.735

22. Zhang S, Huang F, Zhou F, Zhao JW, Wen LJ, Yang PY. Determination of thiols in urinary sample by capillary-column liquid chromatography with amperometric detection at a carbon electrode. Talanta 2002, 58: 451-458. Times Cited: 10. IF: 3.498

23. Gao F, Zhao JW, Zhang S, Zhou F, Jin W, Zhang XM, Yang PY, Zhao DY. Application of C-18-modified mseoporous SBA-15 as the substrate for high performance liquid chromatography. Chemical Journal of Chinese Universities-Chinese 2002, 23: 1494-1497. Times Cited: 9. IF: 0.856

24. Wen LJ, Zhang LY, Zhou F, Lu Y, Yang PY. Quantitative determination of Freon gas using an electronic nose. Analyst 2002, 127: 786-791. Times Cited: 1. IF: 3.969

25. Zhang LY, Wen LJ, Zhou F, Zhang S, Yang PY. Electronic nose for the determination of formaldehyde in air. Chemical Journal of Chinese Universities-Chinese 2003, 24: 1381-1384. Times Cited: 3. IF: 0.856

26. Lu Y, Bian LP, Zhou F, Sun P, Yang PY, Guo YL, Yu CT.Preliminary research on pulsed-electrospray phenomenon. Chemical Journal of Chinese Universities-Chinese 2001, 22: 560-562. Times Cited: 3. IF: 0.856

27. Zhou J, Li P, Zhang S, Long YC, Zhou F, Huang YP, Yang PY, Bao MH. Zeolite-modified microcantilever gas sensor for indoor air quality control Sensors and Actuators B-Chemical 2003, 94: 337-342. Times Cited: 70. IF: 3.535