Shi Qihui
Qihui Shi, Ph.D.
University of California, Santa Barbara; Ph.D. in Chemistry, (2003-2008), Advisor: Galen Stucky
Fudan University (Shanghai, China); B.S. in Chemistry(1999-2003)
Fudan University, Shanghai Medical College, Institutes of Biomedical Sciences Position: Professor & PI (2018.7-present)
Shanghai Jiao Tong University, Shanghai Center for Systems Biomedicine Position: Professor & PI (2011.9-2018.6)
California Institute of Technology, Division of Chemistry and Chemical Engineering，Position: Postdoctoral Research Fellow (2008.9-2011.8)Advisor: Prof. James R. Heath
Institutes of Biomedical Sciences, Fudan University, Shanghai 200032
Email: qihuishi@fudan.edu.cn
New technologies in liquid biopsy and single-cell sequencing
Clinical studies of liquid biopsy-based cancer diagnostics and CDx
Yang L, Yan XW, Chen J, Zhan Q, Hua YQ, Xu SL, Li ZM, Wang Z, Dong Y, Zuo DQ, Xue M, Tang Y, Herschman HR, Lu S*, Shi QH*, Wei W*, Hexokinase 2 discerns a novel circulating tumor cell population associated with poor prognosis in lung cancer patients, Proc. Natl. Acad. Sci. USA, 2021, 118, e2012228118.
Li ZM, Wang Z, Tang Y, Lu X, Chen J, Dong Y, Wu BJ, Wang CY, Yang L, Guo ZL, Xue M, Lu S*, Wei W*, Shi QH*, "Liquid Biopsy-Based Single-Cell Metabolic Phenotyping of Lung Cancer Patients for Informative Diagnostics", Nat. Commun. 2019, 3856
Tang Y, Wang Z, Li ZM, Kim J, Deng YL, Li Y, Heath JR, Wei W*, Lu S*, Shi QH*, "High-throughput screening of rare metabolically active tumor cells in pleural effusion and peripheral blood of lung cancer patients", Proc. Natl. Acad. Sci. USA, 2017,114, 2544-2549.
Wang Z, Zhao YY, Shen XH, Zhao YC, Zhang ZY, Yin HM, Zhao XJ*, Liu HT*, Shi QH*, Single-cell genomics-based molecular algorithm for early cancer detection, Anal. Chem. 2022, 94, 2607–2614.
Chen J, Yang YB, Wang Z, Shen XH, Zhang ZY, Wang CY, Xu HM*, Shi QH*, A multicancer malignant pleural effusion diagnostic test using hexokinase 2 and single-cell sequencing, Clin. Chem. 2022, 68, 680-690.
Wang Z, Chen J, Yang L, Cao MZ, Yu YL, Zhang RL, Quan H, Jiang Q, Hua YQ, Wei W, Lu PH*, Wu J*, Shi QH*, Single-cell sequencing-enabled hexokinase 2 assay for noninvasive bladder cancer diagnosis and screening by detecting rare malignant cells in urine, Anal. Chem. 2020, 92, 16284–16292.
Shi QH, Deng YL, Tang Y, Wang Z, "Method for Detecting and Typing Rare Tumor Cells in Body Fluid Sample and Kit Thereof", U.S. Patent 11,047,858, June 29, 2021.
Shi QH, Lu S, Deng YL, Tang Y, "Method and Device for Detecting Circulating Tumor Cell", U.S. Patent 11,098,264, August 24, 2021.
Shi QH, Wang CY, "Marker of Fetal Trophoblast Cell, Identification Method, Detection Kit and Use Thereof", U.S. Pat. Appl. No. 17/229,686.
