Shang Luoran
Luoran Shang, Ph.D.
B.E. 2013, Southeast University
Ph.D. 2017, Southeast University
Postdoc training, 2017 – 2019, Harvard University
Principal Investigator, since 2019, Fudan University
Institutes of Biomedical Sciences, Fudan University, Shanghai 200032 Tel: +86 -21-54237807
Email: luoranshang@fudan.edu.cn
Lab homepage: https://www.x-mol.com/groups/luoranshang
Dr. Luoran Shang took her undergraduate training at the Southeast University from 2009 to 2013. She then joined the State Key Laboratory of Bioelectronics at Southeast University to pursue her Ph.D. degree under the supervision of Prof. Yuanjin Zhao. After graduation in 2017, Dr. Shang moved to Harvard University and worked as a postdoc in Applied Physics with Prof. David Weitz till 2019. In the Fall of 2019, Dr. Shang joined the Institutes of Biomedical Sciences at Fudan University as a Principal Investigator, and since then has been running the Microfluidics Lab there.
Microfluidics, Bioanalysis, Biomaterials
We focus on droplet microfluidics and the associated applications in biomedical fields, including bioanalysis and the fabrication of functional materials. Microfluidics is the system with integrated channels at the microscale, through which tiny volume of liquids could be systematically manipulated. Droplet microfluidics, as one subcategory, involves the generation of discrete droplets through immiscible multiphase flows inside the microchannels. Droplet microfluidics bring new methods to biomedical research. In the aspect of biochemicalanalysis, because of its advantages of miniaturization and compartmentalization, the droplets can be used as micro-sized reactors for high-throughput detection at single-molecule and single-cell level. In the aspect of material preparation, droplets not only provide a confined space, but also contains a flexible interface. The miniaturized droplets enable precise control of reaction parameters in the process of nucleation and growth of nanoparticles, thereby improving the synthesis efficiency and the monodispersity of the products. Besides, the entire droplets serve as soft templates for preparing microparticles/microcapsules with tailored composition and morphology. We work on the aforementioned aspects of droplet microfluidics, including fluid dynamics, structural colored microparticles for multiplex bioassays, stimuli-responsive microparticles for drug delivery, etc. We also explore some emerging yet exciting areas including aqueous-two-phase systems, microparticles for living cell therapy, and droplet-based protocells.
Zhang ZH, Wang Q, Wang C, Wang JL, Zhao YJ*, ShangLR*, Cholesteric Cellulose Liquid Crystal Ink for 3D Structural Coloration. PNAS, 2022, 119, e2204113119
(Highlighted by American Physical Society)
2. Zhang ZH, Chen ZY, Wang Y, Zhao YJ*, Shang LR*. Cholesteric cellulose liquid crystals with multifunctional structural colors. Advanced Functional Materials 2022, 32, 12, 2107242
3. Chen HX, Bian FK, Wang Y, Zhao YJ*, Shang LR*, Colorimetric photonic tongue for metal ions screening. Matter, 2022, 5, 1590-1602
4. Bian FK, Sun LY, Chen HX, Wang Y, Wang L, Shang LR*, Zhao YJ*. Bioinspired perovskite nanocrystals-integrated photonic crystal microsphere arrays for information security. Advanced Science 2022, 9, 9, 2105278
5. Wang C, Wang Q, Shang LR*. Microfluidic single-cell coating with defined chemomechanical cues for cell therapy. Science Bulletin 2021, 66, 2434-2436
6. Chen HX, Bian FK, Sun LY, Zhang DG, Shang LR*, Zhao YJ*. Hierarchically molecular imprinted porous particles for biomimetic kidney cleaning. Advanced Materials 2020, 32, 2005394
7. Zhao C, Cai LJ, Nie M, Shang LR*, Wang YA*, Zhao YJ*. Cheerios effect inspired microbubbles as suspended and adhered oral delivery systems. Advanced Science 2021, 8, 2004184
8. Shang LR, Yu YR, Gao W, Wang YT, Qu LL, Zhao Z, Chai RJ*, Zhao YJ*. Bio-Inspired Anisotropic Wettability Surfaces from Dynamic Ferrofluid Assembled Templates. Advanced Functional Materials 2018, 28, 1705802
9. Shang LR, Cheng Y, Zhao YJ*. Emerging droplet microfluidics. Chem. Rev. 2017, 117, 7964-8040
10. Shang LR, Fu FF, Cheng Y, Wang H, Liu YX, Zhao YJ*, Gu ZZ*. Photonic crystal microbubbles as suspension barcodes. J. Am. Chem. Soc. 2015, 137, 15533-15539
