Sang Qing
Qing Sang, Ph.D.
Ph.D., 2010-2013, Fudan University
M.S., 2007-2010, Sun Yat-sen University
B.S., 2003-2007, YanTai University
PI, Professor, 2022-now, Fudan University
PI, Associate Professor, 2018-2022, Fudan University
Institutes of Biomedical Sciences, Fudan University, Shanghai 200032 Tel: +86 159 2176 8732
Email: sangqing@fudan.edu.cn
Lab homepage: https://reprod-genet.fudan.edu.cn
Dr. Qing Sang obtained his Ph.D. from Fudan University in 2013. He is now a professor and Ph.D. supervisor in Institutes of Biomedical Sciences, Fudan University. He was awarded as “National Science Fund for Distinguished Young Scholars” in 2023, “National Science Fund for Outstanding Young Scholars” in 2018, “Shanghai Outstanding Academic Leader” in 2020 and “The first prize in Shanghai Natural Science Award in 2020”, and so on. He is now the member of Chinese Society for Zoology, the editorial member of J Assist Reprod Genet.
Genetics of female reproductive diseases, reproductive genetics
Sang’s research mainly focused on investigation of genetic basis and molecular mechanism of diseases responsible for female infertility, including oocyte maturation arrest, early embryonic arrest, Polycystic Ovary Syndrome (PCOS), et al. Till now, 42 papers have been pulished including N Engl J Med, Am J Hum Genet, Protein Cell, Hum Mol Genet, J Clin Endocrinol Metab, J Med Genet.
2020 Shanghai Outstanding Academic Leader
2020 The first prize in Shanghai Natural Science Award
2018 National Science Fund for Outstanding Young Scholars
2017 The youth science and Technology Award by Chinese Society for Zoology
2017 The first prize in National Women’s health Award
2015 The second prize in National Women’s health Award
1.Zhao L, Li Q, Kuang Y, Xu P, Sun X, Meng Q, Wang W, Zeng Y, Chen B, Fu J, Dong J, Zhu J, Luo Y, Gu H, Li C, Li C, Wu L, Mao X, Fan H, Liu R, Zhang Z, Li Q, Du J, He L, Jin L, Wang L*, Sang Q*.Heterozygous loss-of-function variants in LHX8 cause female infertility characterized by oocyte maturation arrest.Genet Med.2022 Aug 26;S1098-3600(22)00873-5.
2.Wang L*, Sang Q*. MOS is a novel genetic marker for human early embryonic arrest and fragmentation. EMBO Mol Med. 2021 Dec 7;13(12):e15323.
3.Zheng W, Zhou Z, Sha Q, Niu X, Sun X, Shi J, Zhao L, Zhang S, Dai J, Cai S, Meng F, Hu L, Gong F, Li X, Fu J, Shi R, Lu G, Chen B, Fan H, Wang L, Lin G*, Sang Q*. Homozygous mutations in BTG4 cause zygotic cleavage failure and female infertility. Am J Hum Genet. 2020 Jul 2;107(1):24-33.
4.Zhao L, Xue S, Yao Z, Shi J, Chen B, Wu L, Sun L, Xu Y, Yan Z, Li B, Mao X, Fu J, Zhang Z, Mu J, Wang W, Du J, Liu S, Dong J, Wang W, Li Q, He L, Jin L, Liang X, Kuang Y, Sun X, Wang L*, Sang Q*. Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development. Protein Cell. 2020 Dec;11(12):921-927.
5.Wang W, Wang W, Xu Y, Shi J, Fu J, Chen B, Mu J, Zhang Z, Zhao L, Lin J, Du J, Li Q, He L, Jin L, Sun X*, Wang L*, Sang Q*. FBXO43 variants in patients with female infertility characterized by early embryonic arrest. Hum Reprod. 2021 Jul 19;36(8):2392-2402.
6.Dong J, Zhang H, Mao X, Zhu J, Li D, Fu J, Hu J, Wu L, Chen B, Sun Y, Mu J, Zhang Z, Sun X, Zhao L, Wang W, Wang W, Zhou Z, Zeng Y, Du J, Li Q, He L, Jin L, Kuang Y, Wang L*, Sang Q*. Novel biallelic mutations in MEI1: expanding the phenotypic spectrum to human embryonic arrest and recurrent implantation failure. Hum Reprod. 2021 Jul 19;36(8):2371-2381.
7.Wang W, Dong J, Chen B, Du J, Kuang Y, Sun X, Fu J, Li B, Mu J, Zhang Z, Zhou Z, Lin Z, Wu L, Yan Z, Mao X, Li Q, He L, Wang L*, Sang Q*. Homozygous mutations in REC114 cause female infertility characterised by multiple pronuclei formation and early embryonic arrest. J Med Genet. 2020 Mar;57(3):187-194.
8.Sang Q*, Zhang Z, Shi J, Sun X, Li B, Yan Z, Xue S, Ai A, Lyu Q, Li W, Zhang J, Wu L, Mao X, Chen B, Mu J, Li Q, Du J, Sun Q, Jin L, He L, Zhu S, Kuang Y*, Wang L*. A pannexin 1 channelopathy causes human oocyte death. Sci Transl Med. 2019 Mar 27;11(485): eaav8731.
9.Sang Q*, Li B, Kuang Y, Wang X, Zhang Z, Chen B, Wu L, Lyu Q, Fu Y, Yan Z, Mao X, Xu Y, Mu J, Li Q, Jin L, He L, Wang L*. Homozygous mutations in WEE2 cause fertilization failure and female infertility. Am J Hum Genet. 2018 Apr 5;102(4):649-657.
10.Feng R#, Sang Q#, Kuang Y#, Sun X#, Yan Z#, Zhang S#, Shi J, Tian G, Luchniak A, Fukuda Y, Li B, Yu M, Chen J, Xu Y, Guo L, Qu R, Wang X, Sun Z, Liu M, Shi H, Wang H, Feng Y, Shao R, Chai R, Li Q, Xing Q, Zhang R, Nogales E, Jin L, He L, Gupta ML Jr, Cowan NJ*, Wang L*. Mutations in TUBB8 and human oocyte meiotic arrest. N Engl J Med. 2016 Jan 21;374(3):223-32.
