Cao Weiqian
Weiqian Cao, Ph.D.
2009.09-2014.06 Ph.D., Chemical Biology, Fudan University, Shanghai, China
2005.09-2009.06 BSc, Biotechnology, Soochow University, Suzhou, China
2020.12-now Associate professor, Institutes of biomedical sciences,Fudan university, Shanghai, China
2020.01-2020.03 Youth visiting scholar, Scripps research institute, USA
2018. 06-2020. 11 Youth associate professor, Institutes of biomedical sciences,Fudan university, Shanghai, China
2017.10-2018.05 Assistant research fellow, Institutes of biomedical sciences,Fudan university, Shanghai, China
2014.07-2017.06 Postdoc at Institutes of Biomedical Sciences, Fudan University, Shanghai, China
Institutes of Biomedical Sciences, Fudan University, Shanghai 200032
Email: wqcao@fudan.edu.cn
Glycoproteomics, glycomics and glycobiology
Proteomics and protein posttranslational modifications
Mass spectrometry analysis
Development of methods for both glycomic and glycoproteomic analysis, especially for the site-specific glycan analysis, including the glycosylation enrichment methods, mass spectrometry-based analytical methods, software tools, and bioinformatics tools.
Development of analytical methods for other PTMs research and targets in glycoproteomic study.
Glycoproteomic-centric multi-omics-based biomarker discovery research
Exploration of biological functions of glycosylation in organism, such as core fucosylation and sialylation.
Zeng W.#,*, Cao W.#, Liu M., He S., Yang P.*, Precise, Fast and Comprehensive Analysis of Intact Glycopeptides and Modified Saccharide Units with pGlyco3, Nature Methods, 2021, 18, 1515.
Yang Y.#, Yan G., Kong S., Wu M., Yang P., Cao W.#,*, Qiao L.*, GproDIA enables data-independent acquisition glycoproteomics with comprehensive statistical control, Nature Communications, 2021, 12, 6073.
Kong S., Zhang Q., Yang L., Huang Y., Liu M., Yan G., Zhao H., Wu M., Zhang X., Yang P.*, Cao W.*, Effective Enrichment Strategy Using Boronic Acid-Functionalized Mesoporous Graphene–Silica Composites for Intact N- and O-Linked Glycopeptide Analysis in Human Serum, Analytical Chemistry, 2021, 93, 6682-6691.
Huang J.#, Wu M.#, Zhang Y., Kong S., Liu M., Jiang B., Yang P.*, Cao W.*, OGP: A Repository of Experimentally Characterized O-Glycoproteins to Facilitate Studies on O-Glycosylation, Genomics, Proteomics & Bioinformatics, 2021, 19, 611-618.
Huang J., Jiang B, Zhao H., Wu M., Kong S., Liu M., Yang P.*, and Cao W.*, Development of a Computational Tool for Automated Interpretation of Intact O-Glycopeptide Tandem Mass Spectra from Single Proteins, Analytical Chemistry, 2020, 92, 6777−6784.
Liu M.#, Zeng W. #, Fang P. #, Cao W. #, Liu C.#, Yan G., Zhang Y., Peng C., Wu J., Zhang X., Tu H., Chi H., Sun R., Cao Y., Dong M., Huang J., Jiang B., Shen H., Wong C. *, He S*., Yang P.*, pGlyco 2.0 enables precision N-glycoproteomics with comprehensive quality control and one-step mass spectrometry for intact glycopeptide identification, Nature Communications, 2017,8,438-451.
