博士,教授,博士生导师
邮箱:ywchu@shmu.edu.cn
验室主页:http://brc.fudan.edu.cn
1.Wang Z#, Lu Z#, Lin S#, Xia J, Zhong Z, Xie Z, Xing Y, Qie J, Jiao M, Li Y, Wen H, Zhao P, Zhang D, Zhou P, Qian J, Luo F, Wang L, Yu H, Liu J, Gu J, Liu R*, Chu Y*. Leucine-tRNA-synthase-2-expressing B cells contribute to colorectal cancer immunoevasion. Immunity. 2022; 55(6):1067-1081.e8.
2.Lu Z#, Liu R#, Wang Y#, Jiao M#, Li Z, Wang Z, Huang C, Shi G, Ke A, Wang L, Fu Y, Xia J, Wen H, Zhou J, Wang X, Ye D, Fan J*, Chu Y*, Cai J*. Ten-eleven translocation-2 inactivation restrains IL-10-producing regμLatory B cells to enable antitumor immunity in hepatocellμLar carcinoma. Hepatology. 2022; doi: 10.1002/hep.32442.
3.Yuedi Wang , Yiyuan Gao , Congyi Niu , Bo Wang , Shushu Zhao , Gils Roex , Jiawen Qian , Jingbo Qie , Lin Chen , Chenhe Yi , Sébastien Anguille , Jie Liu* , Feifei Luo* , Yiwei Chu *. Chimeric antigen receptor clustering via cysteines enhances T-cell efficacy against tumor.Cancer Immunol Immunother. 2022 Apr 19. doi: 10.1007/s00262-022-03195-4.
4.Luman Wang , Damo Xu , Yiwei Chu* . Editorial: Insights into Regulatory B Cells. Front Immunol.2022 Apr 25;13:903711. doi: 10.3389/fimmu.2022.903711.
5.Ying Fu, Luman Wang, Baichao Yu, Damo Xu * , Yiwei Chu *. Immunometabolism shapes B cell fate and functions. Immunology. 2022 Aug;166(4):444-457. doi: 10.1111/imm.13499.
6.Wanwei Zheng #, Huan Song #, Zhongguang Luo #, Hao Wu #, Lin Chen , Yuedi Wang , Haoshu Cui , Yufei Zhang , Bangting Wang , Wenshuai Li , Yao Liu , Jun Zhang , Yiwei Chu *, Feifei Luo *, Jie Liu *. Acetylcholine ameliorates colitis by promoting IL-10 secretion of monocytic myeloid-derived suppressor cells through the nAChR/ERK pathway. PNAS .March 16, 2021,118 (11) e2017762118.
7.Liu J, Li Y, Lu Z, Gu J, Liang Y, Huang E, Wang Z, Zhang H, Wang L, Zhang D, Yu H, Liu R, Chu Y*. Deceleration of glycometabolism impedes IgG-producing B cell-mediated tumor elimination by targeting SATB1. Immunology. 2019 Jan;156(1):56-68.
8.Qian J#, Wang C#, Wang B, Yang J, Wang Y, Luo F, Xu J, Zhao C, Liu R, Chu Y*.The IFN-γ/PD-L1 axis between T cells and tumor microenvironment: hints for glioma anti-PD-1/PD-L1 therapy. J Neuroinflammation. 2018 Oct 17;15(1):290.
9.Yao Y#, Luo F#, Tang C#, Chen D#, Qin Z, Hua W, Xu M, Zhong P, Yu S, Chen D, Ding X, Zhang Y, Zheng X, Yang J, Qian J, Deng Y, Hoon DSB, Hu J, Chu Y*, Zhou L*. Molecular subgroups and B7-H4 expression levels predict responses to dendritic cell vaccines in glioblastoma: an exploratory randomized phase II clinical trial. Cancer Immunol Immunother. 2018 Nov;67(11):1777-1788.
10.Qian J, Luo F, Yang J, Liu J, Liu R, Wang L, Wang C, Deng Y, Lu Z, Wang Y, Lu M, Wang JY, Chu Y*.TLR2 Promotes Glioma Immune Evasion by Downregulating MHC Class II Molecules in Microglia. Cancer Immunol Research. 2018 Oct;6(10):1220-1233.
11.Wang Z, Zhang H, Liu R, Qian T, Liu J, Huang E, Lu Z, Zhao C, Wang L*,Chu Y*.Peyer's patches-derived CD11b+ B cells recruit regulatory T cells through CXCL9 in dextran sulphate sodium-induced colitis. Immunology. 2018 Nov;155(3):356-366.
12.Liu R, Lu Z, Gu J, Liu J, Huang E, Liu X, Wang L, Yang J, Deng Y, Qian J, Luo F, Wang Z, Zhang H, Jiang X, Zhang D, Qian J, Liu G, Zhu H, Qian Y, Liu Z, Chu Y*. MicroRNAs 15A and 16-1 Activate Signaling Pathways That Mediate Chemotaxis of Immune Regulatory B cells to Colorectal Tumors. Gastroenterology. 2018 Feb;154(3):637-651.
13.Lu Z, Liu J, Liu X, Huang E, Yang J, Qian J, Zhang D, Liu R, Chu Y*. MiR-15a/16-1 Suppresses AHR-dependent IL-22 Secretion in CD4+ T cells and Contributes to Immune-mediated Organ Injury. Hepatology. 2018 Mar;67(3):1027-1040.
14.Wang Y, Luo F, Yang J, Zhao C,Chu Y*.New Chimeric Antigen Receptor Design for Solid Tumors. Front Immunol. 2017 Dec 22;8:1934.
15.Yang J, Liu R, Deng Y, Qian J, Lu Z, Wang Y, Zhang D, Luo F, Chu Y*.MiR-15a/16 deficiency enhances anti-tumor immunity of glioma-infiltrating CD8+ T cells through targeting mTOR. Int J Cancer. 2017 Nov 15;141(10):2082-2092.
16.Luo F, Qian J, Yang J, Deng Y, Zheng X, Liu J, Chu Y* (corresponding). Bifunctional αHER2/CD3 RNA-engineered CART-like human T cells specifically eliminate HER2(+) gastric cancer. Cell Research. 2016 Jul;26(7):850-3.
17.Liu X,Jiang X, Liu R, Wang L, Qian T, Zheng Y, Deng Y, Huang E, Xu F, Chu Y*.B cells expressing CD11b effectively inhibit CD4+ T cell responses and ameliorate experimental autoimmune hepatitis in mice. Hepatology. 2015 Nov;62(5):1563-75.
18.L Wang, A Ray, X Jiang, J-y Wang, S Basu, X Liu, T Qian, R He, BN Dittel and Y Chu *.T regulatory cells and B cells cooperate to form a regulatory loop that maintains gut homeostasis and suppresses dextran sulfate sodium-induced colitis .Mucosal Immunology. 2015 Nov;8(6):1297-312.
19.Ronghua Liu, Jie Gu, Pei Jiang, Yijie Zheng, Xiaoming Liu, Xuechao Jiang , Enyu Huang, Shudao Xiong,Fengkai Xu, Guangwei Liu, Di Ge, Yiwei Chu*. DNMT1-microRNA126 epigenetic circuit contributes to esophageal squamous cell carcinoma growth via ADAM9-EGFR-AKT signaling. Clinical Cancer Research, 2015;21(4):854-63.
20.Zhang, Feifei Luo, Yuchan Cai, Nan Liu, Luman Wang, Damo Xu and Chu Yiwei *. TLR1/TLR2 agonist induces tumor regression by reciprocal modulation of effector and regulatory T cells. Journal of Immunology. 2011, 186(4): 1963-9.Faculty of 1000