代表论文

1.Yongchang Zhu^#, Yuanqing Tan^#, Lin Li^#, Yuening Xiang, Yanchao Huang, Xiping Zhang, Jiayong Yin, Jie Li, Fei Lan, Maoxiang Qian^*, Jinchuan Hu^*. Genome-wide mapping of protein–DNA damage interaction by PADD-seq. Nucleic Acids Research, 2023, 51(6): e32.

2.Yanchao Huang^#, Cem Azgar^#, Mengdie Yin, Yi-Ying Chiou, Laura A. Lindsey-Boltz, Aziz Sancar, Jinchuan Hu^*, Ogun Adebali^*. Effects of replication domains on genome-wide UV-induced DNA damage and repair. PLoS Genetics, 2022, 18(9): e1010426.

3.Jiao An^#, Mengdie Yin^#, Jinchuan Hu^*. G-quadruplex and 8-oxo-7,8-dihydroguanine across the genome: methodologies and crosstalk. Genome Instability & Disease, 2022, 3: 241–254.

4.Xiping Zhang, Mengdie Yin, Jinchuan Hu^*. Nucleotide Excision Repair: A Versatile and Smart Toolkit. Acta Biochimica et Biophysica Sinica, 2022, 54(6): 807-819.

5.Sizhong Wu, Yanchao Huang, Christopher P Selby, Meng Gao, Aziz Sancar^*, Jinchuan Hu^*. A new technique for genome-wide mapping of nucleotide excision repair without immunopurification of damaged DNA. Journal of Biological Chemistry, 2022, 298(5): 101863.

6.Liudan Jiang^#, Jiayong Yin^#, Maoxiang Qian^#, Shaoqin Rong, Shengqi Zhang, Kejing Chen, Chengchen Zhao, Yuanqing Tan, Jiayin Guo, Hao Chen, Siyun Gao, Tingting Liu, Yi Liu, Bin Shen, Jian Yang, Yong Zhang, Fei-Long Meng, Jinchuan Hu^*, Honghui Ma^*, Yi-Han Chen^*. UdgX-Mediated Uracil Sequencing at Single-Nucleotide Resolution. Journal of the American Chemical Society, 2022, 144(3): 1323–1331.

7.Jiao An^#, Mengdie Yin^#, Jiayong Yin^#, Sizhong Wu, Christopher P Selby, Yanyan Yang, Aziz Sancar, Guo-Liang Xu, Maoxiang Qian^*, Jinchuan Hu^*. Genome-wide analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine at single-nucleotide resolution unveils reduced occurrence of oxidative damage at G-quadruplex sites. Nucleic Acids Research, 2021, 49(21): 12252-12267.

8.Jinchuan Hu^#, Wentao Li^#*, Ogun Adebali, Yanyan Yang, Onur Oztas, Christopher P. Selby, Aziz Sancar^*. Genome-wide mapping of nucleotide excision repair with XR-seq. Nature Protocols, 2019, 14(1): 248-282.

9.Jinchuan Hu, Christopher P Selby, Sheera Adar, Ogun Adebali, Aziz Sancar^*. Molecular mechanisms and genomic maps of DNA excision repair in Escherichia coli and humans. Journal of Biological Chemistry, 2017, 292(38):15588-15597.

10.Jinchuan Hu^#, Ogun Adebali^#, Sheera Adar, Aziz Sancar^*. Dynamic maps of UV damage formation and repair for the human genome. Proceedings of the National Academy of Sciences of the United States of America, 2017, 114(26): 6758-6763.

11.Jinchuan Hu, Sheera Adar^*. The cartography of UV-induced DNA damage formation and DNA repair. Photochemistry and Photobiology, 2017, 93 (1): 199-206.

12.Jinchuan Hu, Jason D Lieb, Aziz Sancar^*, Sheera Adar^*. Cisplatin DNA damage and repair maps of the human genome at single-nucleotide resolution. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113(41): 11507-11512.

13.Sheera Adar^#, Jinchuan Hu^#, Jason D Lieb^*, Aziz Sancar^*. Genome-wide kinetics of DNA excision repair in relation to chromatin state and mutagenesis. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113(15): E2124-E2133.

14.Jinchuan Hu^#, Sheera Adar^#, Christopher P Selby, Jason D Lieb^*, Aziz Sancar^*. Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution. Genes & Development, 2015, 29(9): 948-960.

15.Jinchuan Hu, Jun-Hyuk Choi, Shobhan Gaddameedhi, Michael G Kemp, Joyce T Reardon, Aziz Sancar^*. Nucleotide excision repair in human cells: fate of the excised oligonucleotide carrying DNA damage in vivo. Journal of Biological Chemistry, 2013, 288(29): 20918–20926.

16.Jinchuan Hu, Li Guo, Kangyun Wu, Bing Liu, Shiwei Lang, Li Huang^*. Template-dependent polymerization across discontinuous templates by the heterodimeric primase from the hyperthermophilic archaeon Sulfolobus solfataricus. Nucleic Acids Research, 2012, 40(8): 3470-3483.