博士，青年研究员，博士生导师
地址：徐汇区东安路131号，上海200032
电话：021-64932808（办公室）
邮箱：duanwu@fudan.edu.cn
ELSEVIER出版社期刊杰出审稿人奖（2016）
美国德克萨斯大学西南医学中心博士后研究奖（2014）
国家自然科学奖二等奖（第2完成人）（2013）
教育部自然科学奖一等奖（第2完成人）（2010）
全国百篇优秀博士论文奖（2012）
全国卢嘉锡优秀研究生奖（2009）
1. Zhang D, Shao J, Lin J, Zhang N, Lu BJ, Lin SC, Dong MQ, Han J (2009). RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science, 325(5938):332-336. (Recommended by F1000Prime)
2. Zhang D, Lin J, Han J (2010). Receptor-interacting protein (RIP) kinase family. Cellular & Molecular Immunology, 7(4):243-249.
3. Han J, Zhong CQ, Zhang D (2011). Programmed necrosis, backup to and competitor with apoptosis in the immune system. Nature Immunology, 12(12):1143-1149.
4. Zhang D#, Zheng M#, Zhao J, Li YY, Huang Z, Li Z, Han J (2011). Multiple death pathways in TNF-treated fibroblasts: RIP3- and RIP1-dependent and independent routes.Cell Research, 21(2):368-371. (# co-first)
5. Lin J, Li H, Yang M, Ren J, Huang Z, Han F, Huang J, Ma J, Zhang D, Zhang Z, Wu J, Huang D, Qiao M, Jin G, Wu Q, Huang Y, Du J, Han J (2013). A role of RIP3-mediated macrophage necrosis in atherosclerosis development. Cell Reports, 3(1):200-210.
6. Wu T, Li Y, Huang D, Han F, Zhang YY, Zhang D*, Han J* (2014). Regulator of G-protein signaling 19 (RGS19) and its partner Gα-inhibiting activity polypeptide 3 (GNAI3) are required for zVAD- induced autophagy and cell death in L929 cells. PLOS One, 9(4):e94634. (*correspondence)
7. Wang T, Zhan X, Bu CH, Lyon S, Pratt D, Hildebrand S, Choi JH, Zhang Z, Zeng M, Wang KW, Turer E, Chen Z, Zhang D, Yue T,..Beutler B (2015). Real-time resolution of point mutations that cause phenovariance in mice. Proc Natl Acad Sci USA, 112(5):E440-E449.
8. Zhang D, Tomisato W, Su L, Sun L, Choi JH, Zhang Z, Wang KW, Zhan X, Choi M, Li X, Tang M, Castro-Perez JM, Hildebrand S, Murray AR, Moresco EMY, Beutler B (2017). Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5. Proc Natl Acad Sci USA, 114(26):E5197-E5206.
9. Choi JH, Wang KW, Zhang D, Zhan X, Wang T, Bu CH, Behrendt CL, Zeng M, Wang Y, Misawa T, Li X, Tang M, Zhan X, Scott L, Hildebrand S, Murray AR, Moresco EM, Hooper LV, Beutler B (2017). IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice. Proc Natl Acad Sci USA, 114(7):E1196-E1204.
10. Zhang D, Yue T, Choi JH, Nair-Gill E, Zhong X, Wang KW, Zhan X, Li X, Choi M, Tang M, Quan J, Hildebrand S, Moresco EMY, Beutler B (2019). Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40. Nature Immunology, 20(10):1322-1334.
11. Wang KW, Zhan X, McAlpine W, Zhang Z, Choi JH, Shi H, Misawa T, Yue T, Zhang D, Wang Y, Ludwig S, Russell J, Tang M, Li X, Murray AR, Moresco EMY, Turer EE, Beutler B (2019). Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice. Proc Natl Acad Sci USA, 116(23):11380-11389.
12. Choi JH, Zhong X, McAlpine W, Liao TC, Zhang D, Fang B, Russell J, Ludwig S, Nair-Gill E, Zhang Z, Wang KW, Misawa T, Zhan X, Choi M, Wang T, Li X, Tang M, Sun Q, Yu L, Murray AR, Moresco EMY, Beutler B (2019). LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. Science, 364(6440): eaau0812.
13. Yue T, Zhan X, Zhang D, Jain R, Wang KW, Choi JH, Misawa T, Su L, Quan J, Hildebrand S, Xu D, Li X, Turer E, Sun L, Moresco EMY, Beutler B (2021). SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell-mediated immunity. Science, 372(6543):eaba4220.
14. Wei G, Zhang H, Zhao H, Wang J, Wu N, Li L, Wu J, Zhang D* (2021). Emerging immune checkpoints in the tumor microenvironment: Implications for cancer immunotherapy. Cancer Letters, 511:68-76. (*correspondence)
15. Yang H, Beutler B*, Zhang D* (2021). Emerging roles of spliceosome in cancer and immunity. Protein & Cell, Jul 1. doi: 10.1007/s13238-021-00856-5. (*correspondence)