1. Xin-Yu Mei*, Da-Shi Qi*, Ting Zhang*, Yin Zhao*, Li Jin, Junli Hou, Jianhua Wang, Yan Lin, Yu Xue, Pingping Zhu, Zexian Liu, Lei Huang, Ji Nie, Wen Si, Jingyi Ma, Jianhong Ye, Richard H. Finnell, Hexige Saiyin, Hong-Yan Wang#, Jian-Yuan Zhao#, Shi-Min Zhao#, and Wei Xu#. Inhibiting Methionyl-tRNA synthetase reduces neural tube defects and congenital heart defects onsets. EMBO Molecular Medicine.(2020)
2. Xia-Di He, Wei Gong, Jia-Nong Zhang, Ji Nie, Cui-Fang Yao, Fu-Shen Guo, Yan Lin, Xiao-Hui Wu, Feng Li, Jie Li, Wei-Cheng Sun, En-Duo Wang, Yan-Peng An, Hui-Ru Tang, Guo-Quan Yan, Peng-Yuan Yang, Yun Wei, Yun-Zi Mao, Peng-Cheng Lin, Jian-Yuan Zhao, Yan-Hui Xu#, Wei Xu#, Shi-Min Zhao# Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations. Cell Metabolism 27(2018)151-166.
3. Feng Li*, Xiadi He*, Dingwei Ye*, Yan Lin, Hongxiu Yu, Cuifang Yao, Lei Huang, Jianong Zhang, Fang Wang, Sha Xu, Xiaohui Wu, Lixia Liu, Chen Yang, Jiaqi Shi, Xiaoyang He, Jie Liu, Yuanyuan Qu, Fushen Guo, Jianyuan Zhao, Wei Xu#, and Shimin Zhao# NADP+-IDH mutations Promote Hypersuccinylation that Impairs Mitochondria Respiration and Induces Apoptosis Resistance. Molecular Cell. 60 (2015), 661-675
4. Ya-Kun Zhang*, Yuan-Yuan Qu*, Yan Lin*, Xiao-Hui Wu, Hou-Zao Chen, Xu Wang, Kai-Qiang Zhou, Yun Wei, Fushen Guo, Cui-Fang Yao, Xia-Di He, Li-Xia Liu, Chen Yang, Zong-Yuan Guan, Shi-Dong Wang, Jianyuan Zhao, De-Pei Liu#, Shi-Min Zhao#, and Wei Xu# Enoyl-CoA Hydratase-1 Regulates mTOR Signaling and Apoptosis by Sensing Nutrients. Nature Communications 8,464,(2017).
5. He, Chang-Liang*,Yang-Yang Bian*,Yu Xue,Ze-Xian Liu,Kai-Qiang Zhou,Cui-Fang Yao, Yan Lin,Han-Fa Zou,Fang-Xiu Luo,Yuan-Yuan Qu,Jian-Yuan Zhao, Ming-Liang Ye,Shi-Min Zhao and Wei Xu#, Pyruvate Kinase M2 Activates mTORC1 by Phosphorylating AKT1S1. Sci Rep 6, 21524, (2016).
6. Xu, W., Li, Y., Liu, C. & Zhao, S. Protein lysine acetylation guards metabolic homeostasis to fight against cancer. Oncogene 33(2014), 2279-2285.
7. Xu W* , Hui Yang*, Ying Liu*, Ying Yang, Ping Wang, Se-Hee Kim, Shinsuke Ito, Chen Yang, Pu Wang, Meng-Tao Xiao, Li-xia Liu, Wen-qing Jiang, Jing Liu, Jin-ye Zhang, Bin Wang, Stephen Frye, Yi Zhang, Yan-hui Xu,Qun-ying Lei, Kun-Liang Guan#, Shi-min Zhao#, and Yue Xiong#. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell19(1) (2010),17-30.
8. Zhao, S-M., Xu, W. *, Jiang, W-Q. *, Yu, W., Lin, Y., Zhang, T-F., Yao, J., Zhou, L., Zeng, Y., Li, H., Li, Y., Shi, J., An, W-L., Hancock, S. M., He, F., Qin, L-X., Chin, J. C., Yang, P-Y., Chen, X., Lei, Q-Y., Xiong, Y. # and Guan, K-L. # Regulation of cellular metabolism by protein lysine acetylation. Science 327 (2010),1000-1004.
9. Zhao, S-M., Li, Y.*, Xu, W. *, Jiang, W-Q. *, Zha, Z-Y., Yu, W., Li, Z-Q., Gong, L-L., Peng, Y-J., Ding, J-P., Lei, Q-Y., Guan, K-L.#, and Xiong, Y. # Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1α. Science 324(2009),261-265.