代表性论文
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  • Liu, M.-X., Jin, L., Sun, S.-J., Liu, P., Feng, X., Cheng, Z.-L., Liu, W.-R., Guan, K.-L., Shi, Y.-H., Yuan, H.-X., and Xiong, Y. (2018) Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma. Oncogene 37, 1637-1653


  • Ye, D., Guan, K.-L., and Xiong, Y. (2018) Metabolism, Activity, and Targeting of D- and L-2-Hydroxyglutarates. Trends in Cancer 4, 151-165

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  • Li, F.-L., Liu, J.-P., Bao, R.-X., Yan, G., Feng, X., Xu, Y.-P., Sun, Y.-P., Yan, W., Ling, Z.-Q., Xiong, Y., Guan, K.-L., and Yuan, H. X. (2018). Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis. Nature Communications, 9(1), 508.


  • Guo, W., Hu, Z., Bao, Y., Li, Y., Li, S., Zheng, Q., Lyu, D., Chen, D., Yu, T., Li, Y., Zhu, X., Ding, J., Zhao, Y., He, X. H., & Huang, S. (2018). A LIN28B Tumor-Specific Transcript in Cancer. Cell Reports, 22(8), 2016-2025.


  • Chen, X.-F., Tian, M.-X., Sun, R.-Q., Zhang, M.-L., Zhou, L.-S., Jin, L., Chen, L.-L., Zhou, W.-J., Duan, K.-L., Chen, Y.-J., Gao, C., Cheng, Z.-L., Wang, F., Zhang, J.-Y., Sun, Y.-P., Yu, H.-X., Zhao, Y.-Z., Yang, Y., Liu, W.-R., Shi, Y.-H., Xiong, Y., Guan, K.-L., and Dan, Y. (2018). SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer. EMBO Reports, e45124.


  • Shan, Z., Tu, Y., Yang, Y., Liu, Z., Zeng, M., Xu, H., Long, J., Zhang, M., Cai, Y., and Wen, W. (2018). Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division. Nature Communications, 9(1), 737.


  • Wang, Z., Zhu, L., Nguyen, T. H. O., Wan, Y., Sant, S., Quinones-Parra, S. M., Crawford, J. C., Eltahla, A. A., Rizzetto, S., Bull, R. A., Qiu, C., Koutsakos, M., Clemens, E. B., Loh, L., Chen, T., Liu, L., Cao, P., Ren, Y., Kedzierski, L., Kotsimbos, T., McCaw, J. M., La Gruta, N. L., Turner, S. J., Cheng, A. C., Luciani, F., Zhang, X., Doherty, P. C., Thomas, P. G., Xu, J., and Kedzierska, K. (2018). Clonally diverse CD38+ HLA-DR+ CD8+ T cells persist during fatal H7N9 disease. Nature Communications, 9(1), 824.

  • Qiu, T., Yang, Y., Qiu, J., Huang, Y., Xu, T., Xiao, H., Wu, D., Zhang, Q., Zhou, C., Zhang, X., Tang, K., Xu, J., and Cao, Z. (2018) CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens. Nature Communications 9

  • Zhao, C., and Xu, J. (2018) Toward universal influenza virus vaccines: from natural infection to vaccination strategy. Current opinion in immunology 53, 1-6

  • Hu, Q., Li, H., Wang, L., Gu, H., & Fan, C. (2018). DNA Nanotechnology-Enabled Drug Delivery Systems. Chemical reviews.

  • Wen, J., Lv, R., Ma, H., Shen, H., He, C., Wang, J., Jiao, F., Liu, H., Yang, P., Tan, L., Lan, F., Shi, Y. G., He, C., Shi, Y., and Diao, J. (2018).Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal. Molecular Cell, 69(6), 1028-1038.

  • Shan, Z., Tu, Y., Yang, Y., Liu, Z., Zeng, M., Xu, H., Long, J., Zhang, M., Cai, Y., and Wen, W. (2018). Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division. Nature Communications, 9(1), 737.

  • Chen, X., Liu, M., Tian, Y., Li, J., Qi, Y., Zhao, D., Wu, Z., Huang, M., Wong, C. C. L., Wang, H.-W., Wang, J., Yang, H., and Xu, Y. (2018) Cryo-EM structure of human mTOR complex 2. Cell Research 28, 518-528.

  • Li, Z., Zhang, J., Liu, X., Li, S., Wang, Q., Chen, D., Hu, Z., Yu, T., Ding, J., Li, J., Yao, M., Fan, J., Huang, S., Gao, Q., Zhao, Y., and He, X. (2018). The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma. Nature Communications, 9(1), 1572.

  • Chen, X., Liu, Z., Shan, Z., Yao, W., Gu, A., and Wen, W. (2018) Structural determinants controlling 14-3-3 recruitment to the endocytic adaptor Numb and dissociation of the Numb center dot alpha-adaptin complex. Journal of Biological Chemistry 293, 4149-4158

  • Chen, B., and Huang, S. (2018) Circular RNA: An emerging non-coding RNA as a regulator and biomarker in cancer. Cancer Letters 418, 41-50

  • Zhang, Y., Yang, Y.-L., Zhang, F.-L., Liao, X.-H., Shao, Z.-M., and Li, D.-Q. (2018) Epigenetic silencing of RNF144A expression in breast cancer cells through promoter hypermethylation and MBD4. Cancer Medicine 7, 1317-1325

  • Wang, H., Liang, L., Dong, Q., Huan, L., He, J., Li, B., Yang, C., Jin, H., Wei, L., Yu, C., Zhao, F., Li, J., Yao, M., Qin, W., Qin, L., and He, X. (2018) Long noncoding RNA miR503HG, a prognostic indicator, inhibits tumor metastasis by regulating the HNRNPA2B1/NF-kappaB pathway in hepatocellular carcinoma. Theranostics 8, 2814-2829

  • Zhu, H., and Sun, A. (2018) Programmed necrosis in heart disease: Molecular mechanisms and clinical implications. Journal of Molecular and Cellular Cardiology 116, 125-134

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