课题组长
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  • 王磊

    博士,教授,博士生导师,复旦大学生命科学学院
    地址:东安路131号,明道楼307室,上海 200032
    电话:021-54237860
    E-mail:wangleiwanglei@fudan.edu.cn

工作经历
教授,复旦大学,生命科学学院(2016.12-至今)
副研究员,复旦大学,生命科学学院(2016.1-2016.12)
副研究员,复旦大学,生物医学研究院(2011.9-2015.12)
助理研究员,复旦大学,生物医学研究院(2009.7-2011.8)
教育经历
博士,上海交通大学,生物技术(2004-2009)
所获奖项
2016年教育部长江学者(青年长江学者)
全国妇幼健康科技奖自然科学二等奖(第一完成人,2015)
上海市科技启明星(2016)
中国遗传学会遗传咨询分会,委员
研究方向
医学遗传学,重点关注人类配子发生及早期胚胎发育异常的遗传学研究
代表论文
  1. Ruizhi Feng*, Qing Sang*, Yanping Kuang*, Xiaoxi Sun*,Zheng Yan*, Shaozhen Zhang*, Juanzi Shi, Guoling Tian, Anna Luchniak, Yusuke Fukuda, Bin Li, Min Yu, Junling Chen,Yao Xu, Luo Guo, Ronggui Qu, Xueqian Wang, Zhaogui Sun, Miao Liu, Huijuan Shi, Hongyan Wang, Yi Feng, Ruijin Shao, Renjie Chai, Qiaoli Li, Qinghe Xing, Rui Zhang, Eva Nogales, Li Jin, Lin He, Mohan L. Gupta, Jr., Nicholas J. Cowan# and Lei Wang#. Mutations in TUBB8 and Human oocyte meiotic arrest. N Engl J Med. 2016; 374:223-32. (#Corresponding author) (IF=59.5)

  2. Yao Xu*, Yingli Shi*, Min Yu*, Jing Fu*, Ruizhi Feng, Qing Sang, Bo Liang, Biaobang Chen, Ronggui Qu, Bin Li, Zheng Yan, Xiaoyan Mao, Yanping Kuang, Li Jin, Lin He, Xiaoxi Sun# and Lei Wang#. Mutations in PADI6 causes female infertility characterized by early embryonic arrest. Am J Hum Genet. 2016, Sep 1;99(3):744-52. (#Corresponding author) (IF=10.8)

  3. Ruizhi Feng, Zheng Yan, Bin Li, Min Yu, Qing Sang, Guoling Tian,Yao Xu , Biaobang Chen, Ronggui Qu, Zhaogui Sun, Xiaoxi Sun, Li Jin, Lin He, Yanping Kuang, Nicholas J. Cowan and Lei Wang*. Mutations in TUBB8 cause a multiplicity of phenotype in human oocytes and early embryos. J Med Genet 2016, Oct;53(10):662-71. (*Corresponding author)  (IF=5.7) (Cover Story)

  4. Sang Q, Zhang J, Feng R, Wang X, Li Q, Zhao X, Xing Q, Chen W, Du J, Sun S, Chai R, Liu D, Jin L, He L, Li H*, Wang L*. Ildr1b is essential for semicircular canal development, migration of the posterior lateral line primordium and hearing ability in zebrafish: implications for a role in the recessive hearing impairment DFNB42. Hum Mol Genet. 2014 Dec 1;23(23):6201-11. (IF=6.39) (*Corresponding author)

  5. Sang Q, Yao Z, Wang H, Feng R, Wang H, Zhao X, Xing Q, Jin L, He L, Wu L*, Wang L*. Identification of microRNAs in human follicular fluid: characterization of microRNAs that govern steroidogenesis in vitro and are associated with polycystic ovary syndrome in vivo. J Clin Endocrinol Metab (IF=6.2). 2013 Jul;98 (7):3068-3079 (*Corresponding author)

  6. Qiaoli Li, Yao Xu,Ruizhi Feng, Haojue Wang, Qing Sang, Qinghe Xing, Xinzhi Zhao, Li Jin, Lin He, and Lei Wang*.  A possible new mechanism in the pathophysiology of polycystic ovary syndrome: The discovery that leukocyte telomere length is strongly associated with PCOS. J Clin Endocrinol Metab (IF=6.2) 2014 Feb;99(2):E234-40. (*Corresponding author)

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