新闻中心
首页 > 新闻中心

第四届发育和疾病的表观遗传学上海国际研讨会通知

发表时间:2018-08-09  |  阅读次数:845次  |  字体大小 [ ]

未标题-1.jpg

第四届发育和疾病的表观遗传学上海国际研讨会 ”将于2018年9月18日-21日在上海中山医院举办。

表观遗传学 (Epigenetics) 是论及决定细胞时代间基因组 转录记忆 的与 DNA 序列改变无关的信号, 介导者和机制的学科。表观遗传事件通过对 DNA 和组蛋白的 共价修饰 , 以转录的 RNA 和翻译的蛋白的方式, 调节和功能化地展示编码在 DNA 序列中遗传的结构信息, 继而产生在 时空多维空间 无限多样的表型。健康表观遗传稳态是确保高等生物发育过程中细胞分化和谱系化正常开展所依据的优态基因组表达的必要前提。基因组表观遗传信息界面的异常是包括肿瘤, 代谢类和神经系统疾病在内的疾患的病因, 病理学机制之一。

为了加大本次大会学术交流的力度, 除了 6 个主题 /26 个 25 分钟报告以外, 我们还安排了 28 个 10 分钟报告, 后者是从两个时长 1.5 小时的墙报摘要者中遴选出来的。欢迎各位与会者积极报名并提交墙报摘要!

会议主题:
主题 1. DNA 修饰的化学和生物学
主题 2. 组蛋白修饰的化学和生物学
主题 3. 转录的化学生物学和表观调控
主题 4. 临床表观遗传学
主题 5. 染色质高级结构的化学和生物学
主题 6. 发育的表观遗传学

未标题-1.jpg
报名参会

演讲嘉宾:

未标题-2.jpg

大会日程:

18th, Sept, 2018    13:00-17:30    会前会
DNA 甲基化专题研讨会
13:00-14:00会议注册
14:00-14:30DNA 甲基化在皮肤病研究中的进(TBD)张学军教授安徽医科大学
14:30-15:00DNA 甲基化在液体活检中的应用戴珩 博士中科普瑞 CTO
15:00-15:30甲基化在鼻咽癌中的预后作用及机制研究柳娜 博士(马骏教授团队)中山大学肿瘤防治中心
15:30-15:50茶歇
15:50-16:20Epigenome-wide association study identifies Behcet's disease-associated methylation loci in Han Chinese于红松 教授遵义医学院
16:20-17:00后基因组时代下的甲基化多组学研究策略李明辉 博士表观星图计划首席科学家中科普瑞科研服务技术产品总监
17:00-17:30互动讨论:表观星图项目朱景德、张学军、柳娜、于红松、戴珩、李明辉
19th, Sept, 2018
8:30-8:40Opening
 I. Chemical and Biological Perspectives of DNA Modifications
Chair of the first half part: Kazu Ushijima (Tokyo)
8:40-9:05A vitamin C-derived DNA modificationGuoliang Xu (Academia Sinica, Shanghai)
9:05-9:25Aging, epigenetic clocks and cancer riskAndrew Teschendorff
9:25-9:50Active DNA Demethylation by Vertebrate DNA MethyltransferasesJames Shen (AcademiaSinica, Taipei)
9:50-10:00The DNA modification landscape of human genome: an experience of HuaXia1 genome/Third-Generation Sequencing.Depeng Wang (Grandomics Biosciences)
10:00-10:10N6-Methyladenine DNA Modification in the Human GenomeChuanle Xiao (Zhongshan Univerisity)
10:10-10:35Break+Group Photograph
 Chair of the second half part: Fei Lan (FuDan University)
10:35-11:00Structural Insight into dynamic regulation of DNA methylationYanhui Xu (FudanUniversity)
11:00-11:25DNA 5-Hydroxymethylcytosines from Cell-free Circulating DNA asDiagnostic Biomarkers for Human CancersXingyu Lu (Shanghai)
11:25-11:35Bisulfite-free, nano-scale analysis of 5-hydroxymethylcytosine at single base resolution.Hu Zeng(Peking  University)
11:35-11:45BRIF-seq: bisulfite-converted randomly integrated    fragments sequencing at single cell levelXiang Li(Huazhong Agricultural University)
11:45-11:55The role of differentially methylated regions in    normal hematopoiesis and leukemogenesisPengxu Qian (Zhejiang  Univerisity)
11:55-13:00Lunch
13:00-14:30Poster session  Chair: Guohong Li 
14:30-14:40Decoding the epigenetic landscape by the histone readers: implications in human diseasesChandrima Das
14:40-14:50Epigenome reprogramming as a basis for combination therapyNaoko Hattori
 II.Chemical and Biological Perspectives of histone    modifications 
Chair of the first half part : Youngjun Kim(Korea,    Seul)
14:50-15:15Structure and Function of YEATS Domain in Health    and DiseaseHaitao Li (TsinghuaUniversity),
15:15-15:40The Dynamic Regulation of Histone MethylationFei Lan (Fudan University)
15:40-16:05De-acetylation and Epigenomic regulationUllas Kolthur-Seetharam (Tata Institute, India)
16:05-16:30Metabolic regulation of gene expressionZhimin Lu (MD Anderson)
16:30-16:50Tea Break
 Chair of the second half part: Lijung Juan(Academia    Sinica, Taipei)
16:50-17:15Epgenetics and Adipogenesis: Implications of    Histone modificationsLanguagesTapas K. Kundu (India)
17:15-17:25UTX functions as an escape from X-inactivation    tumor-suppressor in B cell lymphomaHai Jiang(Academica    Sinica, Shanghai)
17:25-17:35Discovery and Functional Insight of a SIRT6    AllostericXiuyan Yang     (Shanghai Jiao Tong University School of Medicine)
20th, Sept, 2018
 III. Chemical and epigenetic regulation of transcription
Chair of the first half part: Shyam PRABHAKAR    (Singapore)
8:30-8:55R-loopsin physiology and pathologyXiangdong Fu (UCSD)
8:55-9:20Epigenetic Regulation of Hematopoietic Stem Cell    DevelopmentFeng Liu (AcademiaSinica, Beijing)
9:20-9:50The Diversity and Function of Long Noncoding RNAsLingling Chen (AcademiaSinica,Shanghai)
9:50-10:15Cis-acting lncRNAs in transcription and chromatin    regulationXiaohua Shen (TsinghuaUniversity)
10:15-10:40Tea Break
 Chair of the second half part: Hongkui Deng(Peking    University)
10:40-11:05R-loop, the general chromatin feature in    Arabidopsis genomesQianwen Sun (TsinghuaUniversity)
11:05-11:30Re-thinking the coding capacity of non-coding RNAZefeng Wang (AcademiaSinica,Shanghai)
11:30-11:40A long noncoding RNA in telomere maintenance, gene    regulation andinter-chromosomal pairingHsueh-Ping Chu(National TaiwanUniversity)
11:40-11:50Single-cell Landscape during Cell-fate conversionYuin-Han Jonathan LOH
11:50-12:00RNA m6A Modifications in T Cell Differentiation and    InflammationHuabing Li (Shanghai Jiao Tong University School of    Medicine)
12:00-13:10Lunch
 Short-talks     Chair: Yanhui Xu 
13:10-13:20A new layer of rRNA regulation by small    interference RNAs and the nuclear RNAi pathwayShouhong Guang (University of Science and    Technology of China)
13:20-13:30MAnorm2: quantitative comparison of ChIP-seq    samples on group level to identify sex-biased histone modification sitesZhen Shao(AcademiaSinica,Shanghai)
13:30-13:40m6A methyltransferase complex regulates    hematopoietic stem cell self-renewal in the bone marrowBo Zhou(AcademiaSinica,Shanghai)
13:40-13:50Function and mechanism of 2OG-oxygenase JMJD6 in    breast carcinogenesisWen Liu(Xiamen    University )
 IV.Clinical Epigenetics 
 Chair of the first half part : Tapas Kundu(India) 
13:50-14:10Implication of Long Non-coding RNAs in Cancer    BiologyYutaka Kondo (NagoyaUniversity, Japan)
14:10-15:35Global transcriptional memory is mediated by    H3K4me3-Rpd3L HDAC pathwayTaeSoo Kim
15:35-16:00Whole-Genome and Epigenomic Landscapes of    Etiologically DistinctSubtypes of CholangiocarcinomaTeh Bin Tean (CancerCenter, Singapore),
16:00-16:25Functional prediction of causal regulatory variants    identifies a novelautism geneJung Kyoon Choi (Korea)
16:25-16:50Tea Break
 Chair of the second half part: Zefeng Wang(Academia    Sinica) 
16:50-17:15Histone acetylome-wide association study identifies    epigenetic changesand a protective host response mechanism to infectionShyamPRABHAKAR
17:15-17:25Characterization of interaction modes between the    BRM bromodomain and inhibitors in the limit of NMR intermediate exchangeKe Ruan(University of    Science and Technology of China)
17:25-17:35Biochemical Studies and Molecular Dynamic    Simulations Reveal the Molecular Basis of Conformational Changes in DNA    methyltransferase-1 (DNMT1)Shijie Chen(Academia Sinica, Shanghai)
17:35-17:45Drug discovery of protein-protein interactions by    targeting epi-modification sites of untargetable proteinWenchao Lu( Academia Sinica, Shanghai)
21st, Sept, 2018
 V.Chemical and biological perspectives of the    higher-order chromatin structure 
 Chair of the first half part: Young-Joon Kim(Korea) 
8:30-8:55Crosstalk between histone modifications during    heterochromatinassemblyJun-ichi Nakayama(Tokyo,Japan)
8:55-9:20Dynamic regulation of higher-order chromatin    structures in generegulationGuohong Li (AdademiaSinica, Beijing)
9:20-9:45Reprogramming of chromatin architecture in early    mammaliandevelopmentWei Xie (Tsinghua University)
9:45-10:10Combinatorial mechanisms in 3D genome folding and    transcriptionregulationYijun Ruan (Jackson Lab,USA)
10:10-10:30Tea Break
 Chair of the second half part: Lingling    Chen(Academia Sinica, Shanghai) 
10:30-10:55Systematic Mapping of RNA-Chromatin Interactions In    VivoSheng Zhong (UCSD)
10:55-11:05Multisite substrate recognition in Asf1-dependent    acetylation of histone H3 K56 by Rtt109Lin Zhang ( Academia Sinica, Beijing)
11:05-11:153D Genome of Multiple Myeloma Reveals Spatial    Genome Disorganization Associated with Copy Number VariationsCheng Li (Peking University)
11:15-11:25Chromatin remodelling during brain developmentWeijun Feng(Fudan University)
11:25-11:35  
11:35-11:45A novel RNA epigenetic mechanism: m6A RNA-mediated    cell damage responseZhihong Xu(Zhejiang  Univerisity)
11:45-13:00Lunch
 VI. Developmental Epigenetics 
Chair of the first half part: Guoliang Xu(Academia    Sinica, Shanghai) 
13:00-13:25Epigenetic programming by maternal behaviorMoshe Szyf(Canada, McGill University )
13:25-13:50Single-cell multi-omics sequencing of mouse early    embryos andembryonic stem cellsFuchou Tang (PekingUniversity)
13:50-14:00Chromatin accessibility landscape in human early    embryos and its association with evolutionLei Gao(Academia Sinica,    Beijing)
14:00-14:10Dnmt2 mediates intergenerational transmission of    paternally acquired metabolic disorders through sperm small non-coding rnasYunfang Zhang(The Third    Military Medical University)
14:10-14:20lncrna-mir100hg derived mir-100 and mir-125b    mediate cetuximab resistance via wnt/β-catenin    signaling in colorectal cancerYuanyuan Lu(The Fourth    Military Medical University)
14:20-14:30Stella safeguards the oocyte methylome by    preventing excessive de novo methylation mediated by dnmt1Zhuqiang Zhang(Academia Sinica)
14:30-14:50Tea Break
 Chair of the second half part: Xiangdong Fu(UCSD) 
14:50-15:00Spatio-temporal dynamics of chromatin in    developmental hematopoietic cells initiating the oncogenic alterationsDengli Hong(Shanghai Jiao    Tong University School of Medicine)
15:00-15:25Crosstalk of n-a-acetyltransferase and dna    methylation indevelopment and diseaseLi-Jung Juan (AdademiaSinica,Taipei)
15:25-15:50Small molecule-induced cell fate reprogrammingHongkui Deng (Peking University)
15:50-16:00Closing

欲实时把握表观遗传学理论、技术和应用的最新进展,请参加第四届发育和疾病的表观遗传学上海国际研讨会(2018 年 9 月 18-21 日,上海)

时间: 2018-09-18 至 2018-09-21
地点:复旦大学附属中山医院 18 号楼 3 楼福庆厅(上海市徐汇区枫林路 179 号)
联系人: 张老师
邮箱:chris.zhang@bio360.net
电话:021-59555696 / 18516613552(微信同号)

Top