余红秀
博士,复旦大学生物医学研究院研究员、博士生导师,复旦大学附属口腔医院科研处长
地址:上海市东安路131号科研二号楼CB2-064
邮箱:hongxiuyu@fudan.edu.cn
1.Zuojian Hu#, Yingji Chen#, Jielin Lei, Ke Wang, Ziyue Pan, Lei Zhang,Xiayun Xu, Wenhui Li, Lianjun Zhang, Xue Qin, Ronghua Liu, Yiwei Chu, Chenji Wang and Hongxiu Yu. SIRT7 regulates T-cell antitumor immunity through modulation BCAA and fatty acid metabolism. Cell Death and Differentiation, 2025. https://doi.org/10.1038/s41418-025-01490-y.
2.Chengxun Li, Zuguang Xia, Shengjie Li* , Hongxiu Yu*.Antibody-DNA nanostructure conjugate enables targeted delivery of gemcitabine to tumor and improves the anti-tumor efficacy. Chengxun Li Zuguang Xia , Shengjie Li , Hongxiu Yu. Journal of Controlled Release.2025,381,113613.
3.Yanru An#, Yuanyuan Huo#, Zixu Wang, YInqi Dai, Zifeng Wang, Hongxiu Yu*, Zhigan Zhu*. Cryo-microneedle enabled transdermal delivery of two-dimensional Cu (II)-TCPP nanomaterials for synergistic photodynamic-chemodynamic anti-tumor therapy. European Polymer Journal, 2025, 230, 113888.
4.Zuojian Hu, Fenlin Shen,Fenglin Shen, Yang Liu, Ziqing Zhong , Yongling Chen , Zhiyuan Xia, Cuiju Mo,Hongxiu Yu*.Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer. Molecular Oncology, 2024 DO1:10.1002/1878-0261.13791
5.Chengxun Li, Wenzhuo Zhao, Zuojian Hu, Hongxiu Yu*. Cholesterol-modified DNA nanostructures serve as effective non-viral carriers for delivering siRNA to the kidneys to prevent acute kidney injury. Small, 2024, 2311690.
6.Yuan Ren, Yu Deng, Zhengren Wang, Yanyan Li, Hongxiu Yu*, Yidong Zou*, Limin Wu*, Yonghui Deng*. Lab‐on‐Device Synthesis of Hierarchical Macro/Mesoporous WO3 Semiconducting Films for High‐Performance H2S Sensing. Small,2024, 2311659.
7.Zuojian Hu# , Ziyue Pan# , Zhongtong Dai , Wenzhuo Zhao , Chengxun Li , Hongxiu Yu*, Xue Qin*.ω-6 polyunsaturated fatty acids derived lipid mediators promote colorectal cancer growth by providing an immunosuppressive microenvironment. International Immunopharmacology,2023,116, 109818.
8.Cuiping Zhang#, Ke Wang#, Zuojian Hu#, Lujie Yang, Bin Wei, Shan Li, Xue Qin, Pengyuan Yang*, Hongxiu Yu*. SIRT5 is important for bacterial infection by regulating insulin secretion and glucose homeostasis. Protein & cell, 2020, 11(11): 846-851.
9.Fang Wang, Ke Wang, Wei Xu, Shimin Zhao, Dan Ye, Yi Wang, Ying Xu, Lisha Zhou, Yiwei Chu, Cuiping Zhang,Xue Qin, Pengyuan Yang,* and Hongxiu Yu*.SIRT5 Desuccinylates and Activates Pyruvate Kinase M2 to Block Macrophage IL-1b Production and to Prevent DSS-Induced Colitis in Mice. Cell Reports.2017, 19, 2331–2344.
10.Lisha Zhou#, Fang Wang#, Renqiang Sun, Xiufei Chen, Mengli Zhang, Qi Xu, Yi Wang, Shiwen Wang, Yue Xiong, Kun-Liang Guan, Pengyuan Yang, Hongxiu Yu*, Dan Ye*. SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense. EMBO reports, 2016,17(6):811-822.