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申华莉

发表时间:2024-08-29  |  阅读次数:301次  |  字体大小 [ ]
  • 申华莉

    博士,复旦大学生物医学研究院研究员,博士生导师
    地址:东安路131号科研二号楼CB2-064
    邮箱: shenhuali@fudan.edu.cn

工作经历
2019-12 至 今,复旦大学,生物医学研究院,研究员
2012-12 至 2019-12,复旦大学,生物医学研究院,副研究员
2006-07 至 2012-12,复旦大学,生物医学研究院,助理研究员
2009-02 至 2011-02,美国科罗拉多大学,MCDB,访问学者
教育经历
2001-09 至 2006-07,复旦大学,分析化学,博士
1997-09 至 2001-07,复旦大学,化学,学士
研究方向
主要研究方向包括基于质谱的蛋白质组学、脂质组学、单细胞多组学新方法发展,生物标志物的开发,应用多组学技术系统研究生理病理过程等。近五年在以上方向获得国家自然科学基金面上项目、国家重点研发计划、上海市自然科学基金、等多个科研项目资助。
招生专业
化学生物学
代表论文

1. Huiwen Xiong; Chenxin Zhu; Changhao Dai; Xin Ye; Yuanyuan Li; Pintao Li; Shuang Yang; Ghazala Ashraf; Dacheng Wei; Hui Chen; Huali Shen*; Jilie Kong*; Xueen Fang* ; An Alternating Current Electroosmotic Flow‐Based Ultrasensitive Electrochemiluminescence Microfluidic System for Ultrafast Monitoring, Detection of Proteins/miRNAs in Unprocessed Samples, Advanced Science, 2024, 11(6)

2. Shuang Yang; Yutong Han; Yafeng Li; Lei Zhang; Guoquan Yan; Jing Yuan; Qingming Luo; Huali Shen*; Xiaohui Liu*; Rapid and High-Sensitive Phosphoproteomics Elucidated the Spatial Dynamics of the Mouse Brain, Analytical Chemistry, 2023, 95(28): 10703-10712

3. Xia Gao; Ling Lin; Anqi Hu; Heyu Zhao; Le Kang; Xiaoyu Wang; Chunyan Yuan; Pengyuan Yang*; Huali Shen*; Shotgun lipidomics combined targeted MRM reveals sphingolipid signatures of coronary artery disease, Talanta, 2022, 245: 123475

4. Anqi Hu; Lei Zhang; Zhenxin Wang; Chunyan Yuan; Ling Lin; Jiayi Zhang; Xia Gao; Xuguang Chen; Wei Guo*; Pengyuan Yang*; Huali Shen*; Cancer Serum Atlas-Supported Precise Pan-Targeted Proteomics Enable Multicancer Detection, Analytical Chemistry, 2022, 95(2): 862-871

5. Huang, Yuanyu; Zhang, Quanqing; Yang, Lujie; Lin, Ling; Xie, Juanjuan; Yao, Jun; Zhou, Xinwen; Zhang, Lei; Shen, Huali*; Yang, Pengyuan*; Puromycin-Modified Silica Microsphere-Based Nascent Proteomics Method for Rapid and Deep Nascent Proteome Profile, Analytical Chemistry, 2021, 93(16): 6403-6413

6. Juanjuan, Xie; Lei, Zhang; Zhangwei, Chen; Anqi, Hu; Shanshan, Liu; Danbo, Lu; Yan, Xia; Juying, Qian; Pengyuan, Yang; Huali, Shen*; Protein-protein correlations based variable dimension expansion algorithm for high efficient serum biomarker discovery, Analytica Chimica Acta, 2020, 1119(2020): 25-34

7. Fang, Pan; Xie, JuanJuan; Sang, Shaoming; Zhang, Lei; Liu, Mingqi; Yang, Lujie; Xu, Yiteng; Yan, Guoquan; Yao, Jun; Gao, Xing; Qian, Wenjing; Wang, Zhongfeng; Zhang, Yang; Yang, Pengyuan*; Shen, Huali*; Multilayered N-Glycoproteome Profiling Reveals Highly Heterogeneous and Dysregulated Protein N-Glycosylation Related to Alzheimer's Disease, Analytical Chemistry, 2020, 92(1): 867-874

8. Huang, Yuanyu; Zhang, Quanqing; Liu, Yingchao; Jiang, Biyun; Xie, Juanjuan; Gong, Tianqi; Jia, Bin; Liu, Xiaohui; Yao, Jun; Cao, Weiqian; Shen, Huali*; Yang, Pengyuan*; Aperture-controllable nano-electrospray emitter and its application in cardiac proteome analysis, Talanta, 2020, 207(207): 120340

9Lin, Ling; Ding, Ying; Wang, Yi; Wang, Zhenxin; Yin, Xuefei; Yan, Guoquan; Zhang, Lei; Yang, Pengyuan*; Shen, Huali*; Functional Lipidomics: Palmitic Acid Impairs Hepatocellular Carcinoma Development by Modulating Membrane Fluidity and Glucose Metabolism, Hepatology, 2017, 66(2): 432-448

一、      学术专著

Xiangdong Wang; Duojiao Wu; Huali Shen; Lipidomics in Health & Disease - Methods & Application, Springer, 2018.09.28

二、      申请或授权专利

(1) 申华莉; 林灵; 丁颖; 杨芃原; 棕榈酸在制备治疗肝癌和抗肝癌转移药物中的应用, 2019-10-08, 中国, 201310647579.6 (授权专利)

(2) 刘凯; 朱晨鑫; 申华莉; 质谱仪器中机械泵的工况检测方法, 2023-04-28, 中国,CN202310482015.5 (授权专利)

(3) 申华莉; 张嘉益; 一种一体化细胞外囊泡分离柱适配器, 2023-06-16, 中国,CN202310719542.3 (专利,公开中)

(4) 申华莉; 胡安琪; 张磊; 一种肝癌筛查血清生物标志物群及其应用, 2021-12-28, 中国,CN202111623320.9 (专利,实审中)

(5) 申华莉; 胡安琪; 张磊; 多癌筛查血清生物标志物群及其应用, 2021-12-28, 中国,CN202111623336.X (专利,实审中)

 

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